Twins vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for June 21

Odds updated as of 1:16 p.m.

In MLB action on Saturday, the Minnesota Twins play the Milwaukee Brewers.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Twins vs Brewers Game Info

• Minnesota Twins (37-38) vs. Milwaukee Brewers (41-35)
• Date: Saturday, June 21, 2025
• Time: 2:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and FDSWI

Twins vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-134) | MIL: (+114)
• Spread: MIN: -1.5 (+146) | MIL: +1.5 (-178)
• Total: 10 -- Over: (-108) | Under: (-112)

Twins vs Brewers Probable Starting Pitchers

Probable Pitchers: Simeon Woods Richardson (Twins) - 2-3, 5.13 ERA vs José Quintana (Brewers) - 4-2, 3.35 ERA

The probable starters are Simeon Woods Richardson (2-3) for the Twins and Jose Quintana (4-2) for the Brewers. Woods Richardson and his team are 5-4-0 ATS this season when he starts. When Woods Richardson starts a game and his team is the favorite on the moneyline, they have a record of 4-2. The Brewers have gone 5-4-0 against the spread when Quintana starts. The Brewers have a 4-1 record in Quintana's five starts this season when they were the moneyline underdog.

Twins vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (57%)

Twins vs Brewers Moneyline

• Looking at the moneyline for Brewers-Twins, Milwaukee is the underdog at +114, and Minnesota is -134 playing at home.

Twins vs Brewers Spread

• The Brewers are +1.5 on the spread (-178 to cover), and Minnesota is +146 to cover the runline.

Twins vs Brewers Over/Under

• Twins versus Brewers, on June 21, has an over/under of 10, with the over being -108 and the under -112.

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Twins vs Brewers Betting Trends

• The Twins have come away with 25 wins in the 47 contests they have been listed as the favorites in this season.
• Minnesota has a record of 16-7 when favored by -134 or more this year.
• The Twins and their opponents have gone over the total this season in 31 of their 72 opportunities.
• The Twins have an against the spread mark of 39-33-0 in 72 games with a line this season.
• The Brewers have been the underdog on the moneyline 38 total times this season. They've finished 15-23 in those games.
• Milwaukee has a 6-13 record (winning just 31.6% of its games) when it has played as a moneyline underdog of +114 or longer.
• The Brewers have had an over/under set by bookmakers 75 times, and have combined with opponents to go over the total in 30 of those games (30-44-1).
• The Brewers have a 38-37-0 record ATS this season (covering 50.7% of the time).

Twins Player Leaders

• Byron Buxton leads Minnesota in total hits (61) this season while batting .277 with 27 extra-base hits. He has an on-base percentage of .343 and a slugging percentage of .550.
• Among all qualified hitters in MLB, he ranks 42nd in batting average, 58th in on-base percentage, and eighth in slugging.
• Trevor Larnach is hitting .256 with 11 doubles, a triple, 10 home runs and 24 walks. He's slugging .420 with an on-base percentage of .323.
• Among all qualifying hitters, he ranks 79th in batting average, 90th in on-base percentage and 87th in slugging percentage.
• Ty France has hit five homers with a team-high .372 SLG this season.
• France heads into this game with two games in a row with at least one hit. During his last five outings he is batting .176 with two doubles and three RBIs.
• Willi Castro has seven home runs, 17 RBI and a batting average of .286 this season.
• Castro has safely hit in three straight games. In his last five games he is batting .353 with a double and three walks.

Brewers Player Leaders

• Jackson Chourio has racked up a team-best slugging percentage (.463) while pacing the Brewers in hits (85). He's batting .264 and with an on-base percentage of .294.
• Including all qualified players in MLB, his batting average places him 63rd, his on-base percentage ranks 134th, and he is 44th in slugging.
• Chourio hopes to build on a 10-game hitting streak in this matchup. During his last 10 outings he is hitting .333 with four doubles, two triples, two home runs, three walks and eight RBIs.
• Christian Yelich is batting .252 with nine doubles, 14 home runs and 29 walks. He's slugging .441 with an on-base percentage of .330.
• He is 90th in batting average, 76th in on-base percentage and 69th in slugging percentage in the big leagues.
• Sal Frelick is batting .293 with eight doubles, three triples, four home runs and 21 walks.
• Brice Turang has 10 doubles, four home runs and 35 walks while hitting .268.

Twins vs Brewers Head to Head

• 6/20/2025: 17-6 MIL (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/18/2025: 5-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/17/2025: 7-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/16/2025: 3-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/20/2024: 8-4 MIL (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/3/2024: 7-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/2/2024: 3-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/23/2023: 8-7 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/22/2023: 7-3 MIL (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/13/2023: 7-5 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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