Tigers vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 25

Odds updated as of 2:11 a.m.

The Detroit Tigers will face the Cleveland Guardians in MLB action on Sunday.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Tigers vs Guardians Game Info

• Detroit Tigers (33-20) vs. Cleveland Guardians (29-22)
• Date: Sunday, May 25, 2025
• Time: 11:35 a.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: Roku

Tigers vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-240) | CLE: (+198)
• Spread: DET: -1.5 (-108) | CLE: +1.5 (-111)
• Total: 7.5 -- Over: (-105) | Under: (-115)

Tigers vs Guardians Probable Starting Pitchers

Probable Pitchers: Tarik Skubal (Tigers) - 4-2, 2.87 ERA vs Logan Allen (Guardians) - 2-2, 3.86 ERA

This contest's pitching matchup is set, as the Tigers will send Tarik Skubal (4-2) to the mound, while Logan Allen (2-2) will take the ball for the Guardians. Skubal and his team have a record of 5-5-0 against the spread when he starts. Skubal's team has a record of 7-2 this season when he starts and they are the favorite on the moneyline. When Allen starts, the Guardians are 3-5-0 against the spread. The Guardians have been the underdog on the moneyline in five of Allen's starts this season, and they went 2-3 in those matchups.

Tigers vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (67.5%)

Tigers vs Guardians Moneyline

• Cleveland is the underdog, +198 on the moneyline, while Detroit is a -240 favorite at home.

Tigers vs Guardians Spread

• The Guardians are at the Tigers, and are +1.5 on the runline. The Guardians are -108 to cover the spread, and the Tigers are -111.

Tigers vs Guardians Over/Under

• A combined run total of 7.5 has been set for Tigers-Guardians on May 25, with the over at -105 and the under at -115.

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Tigers vs Guardians Betting Trends

• The Tigers have been victorious in 21, or 67.7%, of the 31 contests they have been chosen as favorites in this season.
• Detroit has not lost in three games when named as a moneyline favorite of -240 or better.
• The Tigers and their opponents have gone over the total this season in 26 of their 52 opportunities.
• The Tigers have an against the spread record of 27-25-0 in 52 games with a line this season.
• The Guardians have compiled a 16-14 record in games they were the underdog on the moneyline (winning 53.3% of those games).
• Cleveland has not yet played a game with moneyline odds of +198 or longer.
• The Guardians have played in 49 games with a set over/under, and have combined with their opponents to go over the total 23 times (23-24-2).
• The Guardians have put together a 24-25-0 record ATS this season (covering 49% of the time).

Tigers Player Leaders

• Spencer Torkelson leads Detroit with 44 hits, batting .239 this season with 26 extra-base hits. He has an on-base percentage of .347 and a slugging percentage of .522.
• Among qualifying hitters, he is 108th in batting average, his on-base percentage ranks 55th, and he is 21st in slugging.
• Gleyber Torres leads Detroit in OBP (.374) this season, fueled by 41 hits. He's batting .281 while slugging .432.
• He is 38th in batting average, 27th in on-base percentage and 70th in slugging in MLB.
• Riley Greene has hit 12 homers with a team-high .508 SLG this season.
• Kerry Carpenter is batting .281 with a .314 OBP and 22 RBI for Detroit this season.
• Carpenter has safely hit in three games in a row. During his last five outings he is hitting .250 with two doubles, a home run, two walks and an RBI.

Guardians Player Leaders

• Jose Ramirez paces the Guardians with 57 hits. He's batting .308 and slugging .519 with an on-base percentage of .365.
• Including all the qualifying hitters in MLB, his batting average puts him 14th, his on-base percentage is 36th, and he is 23rd in slugging.
• Ramirez hopes to build on a 17-game hitting streak in this matchup. During his last 10 games he is hitting .372 with two doubles, a triple, three home runs, two walks and eight RBIs.
• Steven Kwan paces his team with a .378 on-base percentage, and has a club-leading .438 slugging percentage. He has a batting average of .320.
• His batting average is sixth among all qualified players, his on-base percentage ranks 24th, and he is 64th in slugging.
• Carlos Santana is hitting .235 with five doubles, six home runs and 27 walks.
• Kyle Manzardo is batting .220 with six doubles, two triples, 10 home runs and 21 walks.

Tigers vs Guardians Head to Head

• 5/24/2025: 7-5 CLE (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/23/2025: 3-1 CLE (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/22/2025: 7-0 CLE (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 10/12/2024: 7-3 CLE (Favorite: Tigers, Spread: -1.5, Total: 6, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/10/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 10/9/2024: 3-0 DET (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/7/2024: 3-0 DET (Favorite: Tigers, Spread: -1.5, Total: 6, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 10/5/2024: 7-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/30/2024: 5-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/29/2024: 8-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)

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