Tennessee vs Mississippi State Prediction, Odds, Picks, Best Bets for Week 5 2025

In college football action on Saturday, the Tennessee Volunteers take on the Mississippi State Bulldogs.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

Tennessee vs Mississippi State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Tennessee: (-275) | Mississippi State: (+220)
• Spread: Tennessee: -7.5 (-102) | Mississippi State: +7.5 (-120)
• Total: 62.5 -- Over: (-110) | Under: (-110)

Tennessee vs Mississippi State Betting Trends

• Against the spread, Tennessee is 3-1-0 this year.
• As at least a 7.5-point favorite, Tennessee has two wins ATS (2-1).
• All four of Tennessee's games have gone over the point total this season.
• Against the spread, Mississippi State is 4-0-0 this season.
• One Mississippi State game (out of four) has gone over the point total this year.

Tennessee vs Mississippi State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Volunteers win (73.8%)

Tennessee vs Mississippi State Point Spread

Tennessee is favored by 7.5 points versus Mississippi State. Tennessee is -102 to cover the spread, while Mississippi State is -120.

Tennessee vs Mississippi State Over/Under

The Tennessee-Mississippi State game on Sept. 27 has been given an over/under of 62.5 points. The over is -110 and the under is -110.

Tennessee vs Mississippi State Moneyline

Looking at the moneyline for Mississippi State-Tennessee, Mississippi State is the underdog at +220, and Tennessee is -275.

Tennessee vs. Mississippi State Points Insights

Tennessee vs. Mississippi State Game Info

• Game day: Saturday, September 27, 2025
• Game time: 4:15 p.m. ET
• TV channel: SEC Network
• Location: Starkville, Mississippi
• Stadium: Davis Wade Stadium at Scott Field

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Check out even more in-depth Tennessee vs. Mississippi State analysis on FanDuel Research.