Spurs vs. Trail Blazers NBA Playoffs Prediction, Odds, Picks, Best Bets for April 28

Spurs vs. Trail Blazers Game Info

• Date: Tuesday, April 28, 2026
• Time: 9:30 p.m. ET
• Venue: Frost Bank Center -- San Antonio, Texas
• Coverage: ESPN

The San Antonio Spurs are double-digit 11.5-point favorites in a decisive Game 5 of the opening round of the NBA Playoffs against the Portland Trail Blazers at Frost Bank Center on Tuesday, tipping off at 9:30 p.m. ET on ESPN. The Spurs hold a 3-1 series lead. The matchup has an over/under set at 216.5 points.

Spurs vs. Trail Blazers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Spurs vs. Trail Blazers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Spurs win (76.3%)

Spurs vs. Trail Blazers Betting Trends

• The Spurs have put together a 43-34-4 record against the spread this season.
• The Trail Blazers have 45 wins against the spread in 82 games this year.
• Spurs games have finished with a final combined score above the over/under 36 times this season.
• Trail Blazers games this season have eclipsed the over/under 42 times in 82 opportunities (51.2%).
• San Antonio has done a better job covering the spread on the road (24-17-1) than it has in home games (19-17-3).
• At home, the Spurs go over the total 45% of the time (18 of 40 games). They've hit the over in 42.9% of games on the road (18 of 42 contests).
• Portland's winning percentage against the spread at home is .610 (25-16-0). On the road, it is .488 (20-21-0).
• Looking at the over/under, Trail Blazers games have finished over more frequently at home (25 of 41, 61%) than away (17 of 41, 41.5%).

Spurs Leaders

• Victor Wembanyama's numbers on the season are 25 points, 11.5 boards and 3.1 assists per game, shooting 51.2% from the floor and 34.9% from downtown, with an average of 1.9 made treys.
• De'Aaron Fox's numbers on the season are 18.6 points, 3.8 boards and 6.2 assists per game, shooting 48.6% from the field and 33.2% from beyond the arc, with an average of 1.8 made treys.
• Stephon Castle is averaging 16.6 points, 7.4 assists and 5.3 rebounds.
• Keldon Johnson averages 13.2 points, 5.4 boards and 1.4 assists, shooting 51.9% from the field and 36.3% from downtown, with 1.2 made 3-pointers per contest.
• Julian Champagnie is averaging 11.1 points, 5.8 rebounds and 1.5 assists. Defensively, he averages 0.8 steals and 0.5 blocked shots.

Trail Blazers Leaders

• Per game, Deni Avdija provides the Trail Blazers 24.2 points, 6.9 rebounds and 6.7 assists. He also averages 0.8 steals and 0.6 blocks.
• The Trail Blazers receive 12.1 points per game from Donovan Clingan, plus 11.6 rebounds and 2.1 assists.
• Toumani Camara's numbers on the season are 13.4 points, 5.1 rebounds and 2.5 assists per game. He is draining 44% of his shots from the floor and 37% from beyond the arc, with an average of 2.7 triples.
• The Trail Blazers get 16.3 points per game from Jrue Holiday, plus 4.6 boards and 6.1 assists.
• Per game, Jerami Grant gets the Trail Blazers 18.6 points, 3.5 boards and 2.1 assists, plus 0.7 steals and 0.6 blocks.

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