Seton Hall vs Creighton College Basketball Prediction, Odds, Picks, Best Bets for Big East Tournament

The No. 4 seed Seton Hall Pirates (20-11, 10-10 Big East) are squaring off against the No. 5 seed Creighton Bluejays (15-16, 9-11 Big East) in the Big East tournament on Thursday at Madison Square Garden, at 2:30 p.m. ET airing on Peacock.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Seton Hall vs. Creighton Game Info and Odds

• Game day: Thursday, March 12, 2026
• Game time: 2:30 p.m. ET
• TV channel: Peacock
• Location: New York City, New York
• Arena: Madison Square Garden

Seton Hall vs. Creighton Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Seton Hall win (65.1%)

Here's a look at some betting trends for Seton Hall (-3.5) versus Creighton on Thursday. The total is set at 132.5 points for this game.

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Seton Hall vs. Creighton: ATS Betting Stats and Trends

• Seton Hall has won 18 games against the spread this season, while failing to cover 13 times.
• Creighton has covered 10 times in 31 games with a spread this season.
• Seton Hall covers the spread when it is a 3.5-point favorite or more 46.7% of the time. That's more often than Creighton covers as an underdog of 3.5 or more (33.3%).
• Against the spread, the Pirates have performed worse when playing at home, covering six times in 17 home games, and nine times in 11 road games.
• The Bluejays have performed better against the spread on the road (5-7-0) than at home (4-12-0) this year.
• Seton Hall is 11-9-0 against the spread in conference games this year.
• Creighton has six wins against the spread in 20 Big East games this season.

Seton Hall vs. Creighton: Moneyline Betting Stats

• Seton Hall has won in 17, or 81%, of the 21 contests it has been named as the moneyline favorite in this year.
• This season, the Pirates have been victorious 14 times in 16 chances when named as a favorite of at least -164 or shorter on the moneyline.
• Creighton has a 4-10 record in games it was the underdog on the moneyline (winning 28.6% of those games).
• When playing as a moneyline underdog with odds of +136 or longer, the Bluejays have a 2-6 record (winning only 25% of their games).
• The moneyline set for this matchup implies Seton Hall has a 62.1% chance of walking away with the win.

Seton Hall vs. Creighton Head-to-Head Comparison

• Seton Hall is outscoring opponents by 5.3 points per game with a +164 scoring differential overall. It puts up 70.4 points per game (295th in college basketball) and allows 65.1 per outing (12th in college basketball).
• Adam Clark's team-leading 12.4 points per game ranks 647th in the country.
• Creighton has a +14 scoring differential, putting up 75.6 points per game (180th in college basketball) and conceding 75.1 (218th in college basketball).
• Josh Dix's 12.7 points per game paces Creighton and ranks 595th in the country.
• The Pirates record 32.7 rebounds per game (133rd in college basketball) while conceding 30.0 per outing to their opponents. They outrebound opponents by 2.7 boards per game.
• Stephon Payne III tops the Pirates with 6.6 rebounds per game (208th in college basketball play).
• The Bluejays average 31.8 rebounds per game (193rd in college basketball), compared to the 32.7 of their opponents.
• Jasen Green tops the Bluejays with 5.9 rebounds per game (306th in college basketball).
• Seton Hall's 93.2 points per 100 possessions on offense rank 285th in college basketball, and the 86.2 points it allows per 100 possessions rank 18th in college basketball.
• The Bluejays record 97.9 points per 100 possessions (176th in college basketball), while giving up 97.4 points per 100 possessions (242nd in college basketball).

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