Reds vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for June 29

Odds updated as of 12:11 a.m.

The Cincinnati Reds are among the MLB squads in action on Sunday, versus the San Diego Padres.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Reds vs Padres Game Info

• Cincinnati Reds (43-40) vs. San Diego Padres (45-37)
• Date: Sunday, June 29, 2025
• Time: 1:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and SDPA

Reds vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-132) | SD: (+112)
• Spread: CIN: -1.5 (+158) | SD: +1.5 (-192)
• Total: 9.5 -- Over: (+104) | Under: (-128)

Reds vs Padres Probable Starting Pitchers

Probable Pitchers: Nick Lodolo (Reds) - 5-5, 3.63 ERA vs Stephen Kolek (Padres) - 3-3, 3.95 ERA

The Reds will give the ball to Nick Lodolo (5-5, 3.63 ERA), who is eyeing win No. 6 on the season, and the Padres will turn to Stephen Kolek (3-3, 3.95 ERA). Lodolo's team is 7-7-0 against the spread in his starts this season. When Lodolo starts a game and his team is the favorite on the moneyline, they have a record of 3-4. The Padres have a 6-4-0 record against the spread in Kolek's starts. The Padres are 1-3 in Kolek's four starts this season that they were the underdog on the moneyline.

Reds vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (54.3%)

Reds vs Padres Moneyline

• The Reds vs Padres moneyline has Cincinnati as a -132 favorite, while San Diego is a +112 underdog on the road.

Reds vs Padres Spread

• The Padres are at +1.5 on the runline against the Reds. The Padres are -192 to cover the spread, and the Reds are +158.

Reds vs Padres Over/Under

• A combined run total of 9.5 has been set for Reds-Padres on June 29, with the over at +104 and the under at -128.

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Reds vs Padres Betting Trends

• The Reds have come away with 16 wins in the 32 contests they have been listed as the favorites in this season.
• This season Cincinnati has come away with a win eight times in 14 chances when named as a favorite of at least -132 on the moneyline.
• Contests with the Reds have gone over the total set by bookmakers in 35 of 79 chances this season.
• The Reds have an against the spread record of 42-37-0 in 79 games with a line this season.
• The Padres have a 17-20 record in games they were the underdog on the moneyline (winning 45.9% of those games).
• San Diego has gone 14-15 when playing as a moneyline underdog with odds of +112 or longer (48.3%).
• The Padres have combined with opponents to go over the total 34 times this season for a 34-44-3 record against the over/under.
• The Padres have a 43-38-0 record against the spread this season (covering 53.1% of the time).

Reds Player Leaders

• Elly De La Cruz leads Cincinnati in slugging percentage (.506) and total hits (88) this season. He's batting .277 with an on-base percentage of .353.
• Among qualified hitters, he ranks 47th in batting average, his on-base percentage ranks 49th, and he is 20th in slugging.
• TJ Friedl has 87 hits this season and a team-best OBP of .377. He's batting .288 and slugging .424.
• He ranks 27th in batting average, 20th in on-base percentage and 81st in slugging among qualifying hitters.
• Spencer Steer is batting .249 with a .399 slugging percentage and 31 RBI this year.
• Steer has logged a hit or more in seven games in a row. During his last 10 outings he is hitting .425 with three doubles, a triple, four home runs and nine RBIs.
• Gavin Lux is batting .271 with a .357 OBP and 37 RBI for Cincinnati this season.
• Lux takes a four-game hitting streak into this game. During his last five outings he is batting .357 with a double, a home run and five RBIs.

Padres Player Leaders

• Manny Machado has put up a team-best OBP (.357) and slugging percentage (.486), and leads the Padres in hits (93, while batting .297).
• Including all qualifying hitters in MLB, he ranks 17th in batting average, 41st in on-base percentage and 31st in slugging percentage.
• Fernando Tatis Jr. is batting .257 with 11 doubles, a triple, 15 home runs and 38 walks. He's slugging .446 with an on-base percentage of .346.
• Including all qualifying players, his batting average puts him 82nd, his on-base percentage is 55th, and he is 62nd in slugging.
• Luis Arraez is batting .283 with 16 doubles, four triples, four home runs and 13 walks.
• Gavin Sheets has 14 doubles, a triple, 13 home runs and 22 walks while hitting .265.

Reds vs Padres Head to Head

• 6/28/2025: 6-4 SD (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/27/2025: 8-1 CIN (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/23/2024: 6-4 SD (Favorite: Padres, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/22/2024: 7-3 SD (Favorite: Padres, Spread: -1.5, Total: 9.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/21/2024: 2-0 CIN (Favorite: Padres, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/1/2024: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/30/2024: 6-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/29/2024: 5-2 CIN (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/2/2023: 4-3 CIN (Favorite: Reds, Spread: -1.5, Total: 11, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/1/2023: 12-5 SD (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -162, Underdog Moneyline: +136)

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