Rays vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 15

Odds updated as of 7:11 p.m.

Wednesday's slate in the MLB includes a matchup between the Tampa Bay Rays and the Chicago White Sox.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Rays vs White Sox Game Info

• Tampa Bay Rays (9-7) vs. Chicago White Sox (6-11)
• Date: Wednesday, April 15, 2026
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN+ and Rays.TV

Rays vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-116) | CHW: (-102)
• Spread: TB: -1.5 (+146) | CHW: +1.5 (-178)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Rays vs White Sox Probable Starting Pitchers

Probable Pitchers: Cole Sulser (Rays) - 1-0, 6.00 ERA vs Sean Burke (White Sox) - 0-1, 3.60 ERA

This contest's pitching matchup is set, as the Rays will send Cole Sulser (1-0) to the mound, while Sean Burke (0-1) will answer the bell for the White Sox. Sulser did not pitch in a game with a spread last season. Sulser did not appear in a game when his team was the moneyline favorite last season. Burke has started two games with set spreads, and the White Sox failed to cover in both opportunities. The White Sox were the moneyline underdog for two Burke starts this season -- they lost both.

Rays vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (60.1%)

Rays vs White Sox Moneyline

• Looking at the moneyline for Rays-White Sox, Tampa Bay is the favorite at -116, and Chicago is -102 playing at home.

Rays vs White Sox Spread

• The White Sox are +1.5 on the run line against the Rays. The White Sox are -178 to cover, and the Rays are +146.

Rays vs White Sox Over/Under

• A total of 8.5 runs has been set for the Rays-White Sox game on April 15, with the over available at -102 and the under at -120.

Bet on Tampa Bay Rays vs. Chicago White Sox on FanDuel today!

Rays vs White Sox Betting Trends

• The Rays have won in four of the eight contests they have been named as odds-on favorites in this year.
• Tampa Bay has a record of 3-2 when favored by -116 or more this year.
• Contests with the Rays have gone over the total set by bookmakers in 12 of 16 chances this season.
• The Rays are 9-7-0 against the spread in their 16 games with a line set by sportsbooks this season.
• The White Sox have been the underdog on the moneyline 16 total times this season. They've finished 5-11 in those games.
• Chicago has gone 5-11 when playing as a moneyline underdog with odds of -102 or longer (31.2%).
• In the 16 games bookmakers have set an over/under for the White Sox, they have combined with opponents to go over the total nine times (9-7-0).
• The White Sox have a 6-10-0 record ATS this season (covering just 37.5% of the time).

Rays Player Leaders

• Yandy Diaz leads Tampa Bay in OBP (.452) and total hits (23) this season. He's batting .365 batting average while slugging .556.
• Among qualified hitters in MLB, his batting average ranks third, his on-base percentage ranks fourth, and he is 20th in slugging.
• Diaz has recorded a base hit in four straight games. During his last five outings he is batting .316 with a home run, two walks and five RBIs.
• Chandler Simpson has hit zero homers this season while driving in four runs. He's batting .407 this season and slugging .475 with an on-base percentage of .435.
• Among all qualified hitters, he ranks first in batting average, eighth in on-base percentage and 52nd in slugging percentage.
• Simpson enters this game looking to extend his nine-game hit streak. During his last 10 outings he is batting .368 with a triple, a walk and three RBIs.
• Jonathan Aranda is batting .222 with a .413 slugging percentage and 14 RBI this year.
• Junior Caminero has two home runs, four RBI and a batting average of .233 this season.

White Sox Player Leaders

• Munetaka Murakami has an on-base percentage of .343 and has nine hits, both team-high numbers for the White Sox. He's batting .167 and slugging .444.
• Including all the qualified hitters in the big leagues, his batting average puts him 169th, his on-base percentage is 76th, and he is 69th in slugging.
• Miguel Vargas is batting .167 with three doubles, a triple, a home run and 10 walks. He's slugging .315 with an on-base percentage of .313.
• Including all qualifying hitters, his batting average places him 169th, his on-base percentage ranks 117th, and he is 134th in slugging.
• Colson Montgomery is hitting .186 with three doubles, three home runs and five walks.
• Chase Meidroth paces his team with a .305 slugging percentage.

Rays vs White Sox Head to Head

• 4/14/2026: 8-5 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/11/2025: 5-1 CHW (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/10/2025: 6-5 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/9/2025: 5-4 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/23/2025: 11-9 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 7/21/2025: 8-3 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/8/2024: 4-1 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/7/2024: 5-1 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 5/6/2024: 8-2 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/28/2024: 4-2 CHW (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!