Purdue vs USC Basketball Prediction, Odds, Picks, Best Bets for Big Ten Tournament

The No. 6 seed Purdue Boilermakers (21-10, 13-7 Big Ten) head into the Big Ten tournament against the No. 14 seed USC Trojans (16-16, 7-13 Big Ten) on Thursday at Gainbridge Fieldhouse, starting at 9 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Purdue vs. USC Game Info and Odds

• Game day: Thursday, March 13, 2025
• Game time: 9 p.m. ET
• TV channel: Big Ten Network
• Location: Indianapolis, Indiana
• Arena: Gainbridge Fieldhouse

Purdue vs. USC Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Purdue win (77.9%)

Take a look at some betting trends and insights for Purdue (-9.5) versus USC on Thursday. The over/under is set at 149.5 points for this game.

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Purdue vs. USC: ATS Betting Stats and Trends

• Purdue has won 17 games against the spread this season, while failing to cover 14 times.
• USC has won 13 games against the spread this season, while failing to cover 19 times.
• As a 9.5-point underdog or more in 2024-25, USC is 1-3 against the spread compared to the 4-5 ATS record Purdue puts up as a 9.5-point favorite.
• The Boilermakers have done a better job covering the spread at home (10-6-0) than they have in road tilts (6-5-0).
• In 2024-25 against the spread, the Trojans have a better winning percentage at home (.421, 8-11-0 record) than on the road (.400, 4-6-0).
• Purdue's record against the spread in conference action is 13-7-0.
• USC has nine wins against the spread in 21 Big Ten games this season.

Purdue vs. USC: Moneyline Betting Stats

• Purdue has been chosen as the moneyline favorite in 23 games this year and has walked away with the win 19 times (82.6%) in those games.
• The Boilermakers have not lost in eight games this year when favored by -529 or better on the moneyline.
• USC has won 23.5% of the games this season it was the moneyline underdog (4-13).
• When they have played as a moneyline underdog with odds of +390 or longer, the Trojans have a 1-2 record (winning only 33.3% of their games).
• Purdue has an implied victory probability of 84.1% according to the moneyline set for this matchup.

Purdue vs. USC Head-to-Head Comparison

• Purdue has a +237 scoring differential, topping opponents by 7.7 points per game. It is putting up 78.3 points per game to rank 73rd in college basketball and is giving up 70.6 per outing to rank 135th in college basketball.
• Purdue's leading scorer, Trey Kaufman-Renn, is 26th in the country scoring 19.7 points per game.
• USC's +51 scoring differential (outscoring opponents by 1.6 points per game) is a result of putting up 77.1 points per game (94th in college basketball) while giving up 75.5 per contest (284th in college basketball).
• Desmond Claude's 16.2 points per game leads USC and ranks 174th in the nation.
• The Boilermakers record 29.5 rebounds per game (316th in college basketball) while conceding 28.1 per outing to their opponents. They outrebound opponents by 1.4 boards per game.
• Kaufman-Renn averages 6.1 rebounds per game (ranking 295th in college basketball) to lead the Boilermakers.
• The 28.7 rebounds per game the Trojans accumulate rank 334th in the country. Their opponents grab 29.0.
• Saint Thomas is 364th in the country with 5.8 rebounds per game, leading the Trojans.
• Purdue scores 105.3 points per 100 possessions (17th in college basketball), while giving up 95.0 points per 100 possessions (229th in college basketball).
• The Trojans rank 82nd in college basketball with 100.0 points scored per 100 possessions, and 304th defensively with 98.0 points conceded per 100 possessions.

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