Premier League Betting: Best Bets and Player Props for Matchweek 5

The English Premier League's 2025-26 campaign has arrived.

When looking at the EPL soccer odds at FanDuel Sportsbook, which bets make the most sense for this matchweek?

Premier League Best Bets for Matchweek 5

Leeds at Wolves

Draw (+200)

Things have gotten dark early for Wolves, and while there's a lot of season left, I don't think it's overdoing it to say this is a massive game for them.

But it's also a big game for Leeds, a promoted side that will be in the relegation mix alongside Wolves.

With so much on the line for both sides, I think it'll lead to a draw.

Wolves have zero points and just two goals through four rounds. They've been about as bad as you can be, and they've moved to second favorites to suffer the drop (-170) after starting the year with +300 odds to be relegated.

Leeds have been better than Wolves -- especially defensively -- but not significantly so. Leeds have mustered just one goal through four matches but have managed a win and a draw to notch four points.

I don't think much separates these sides. Both will be desperate not to lose on Saturday, and neither team has much upside in attack, pushing me toward a draw at +200.

Newcastle at Bournemouth

Bournemouth Moneyline (+130)

Newcastle gave a good account of themselves Thursday against Barcelona, losing 2-1 at home in an emotionally charged atmosphere. Now they have a quick turnaround for Sunday's road match at Bournemouth, and it's the longest trip they'll make in the league this season.

It's a bad break in the scheduling department for the Magpies, who will also be sans Anthony Gordon (suspended), and I think it all adds up to a win for the Cherries.

Even without the rest advantage, Bournemouth is fully capable of winning this match. The Cherries (+2.5) are ahead of Newcastle (+2.3) in expected goal difference, per FBRef, and Bournemouth picked up a win and a draw over two fixtures with Newcastle last campaign.

Plus, Newcastle still don't have their best XI available. Aside from Gordon's ban, big signing Nick Woltemade isn't yet fully fit as he hasn't played more than 45 minutes in a match with the Mags.

I'll happily take Bournemouth to win at +130.

Get a 30% Profit Boost Token for ANY wager on any soccer matches taking place on September 19th through 21st! See here for full terms and conditions. Learn about today’s other offers at FanDuel Sportsbook Promos.

Looking for more soccer betting opportunities? Head over to FanDuel Sportsbook to check out all of the soccer odds.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.