Pittsburgh vs West Virginia Prediction, Odds, Picks, Best Bets for Week 3 2025

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The college football schedule on Saturday includes the Pittsburgh Panthers facing the West Virginia Mountaineers.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Pittsburgh vs West Virginia Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Pittsburgh: (-275) | West Virginia: (+220)
Spread: Pittsburgh: -7.5 (-105) | West Virginia: +7.5 (-115)
Total: 55.5 -- Over: (-110) | Under: (-110)

Pittsburgh has posted two wins against the spread this season.
Pittsburgh has yet to lose ATS (2-0) as a 7.5-point favorite or greater this year.
Pittsburgh and its opponent have not failed to hit the over in any game this season.
West Virginia has posted one win against the spread this season.
No West Virginia game has gone over the point total this year.

All college football win probability predictions and picks are according to numberFire.
Prediction: Panthers win (64.2%)

West Virginia is an underdog by 7.5 points versus Pittsburgh. West Virginia is -115 to cover the spread, and Pittsburgh is -105.

The over/under for the Pittsburgh versus West Virginia game on Sept. 13 has been set at 55.5, with -110 odds on the over and -110 odds on the under.

Looking at the moneyline for West Virginia-Pittsburgh, West Virginia is the underdog at +220, and Pittsburgh is -275.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Total Games
Pittsburgh	53.0	13	13.0	37	53.0	2
West Virginia	27.5	77	10.0	22	57.0	2

Check out even more in-depth Pittsburgh vs. West Virginia analysis on FanDuel Research.

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