Pistons vs. 76ers Prediction, Odds, Picks, Best Bets for March 12

Pistons vs. 76ers Game Info

• Date: Thursday, March 12, 2026
• Time: 7 p.m. ET
• Venue: Little Caesars Arena -- Detroit, Michigan
• Coverage: Amazon Prime Video and NBCS-PH

The Philadelphia 76ers (35-30) are heavy underdogs (by 15.5 points) to break a three-game road losing streak when they visit the Detroit Pistons (46-18) on Thursday, March 12, 2026 at 7 p.m. ET. The matchup has a point total of 222.5.

Pistons vs. 76ers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Pistons vs. 76ers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Pistons win (77.4%)

Pistons vs. 76ers Betting Trends

• The Pistons have put together a 33-29-1 record against the spread this season.
• The 76ers have played 65 games, with 32 wins against the spread.
• This season, 29 of the Pistons' games have gone over the point total out of 65 chances.
• 76ers games this year have gone over the point total 34 times in 65 opportunities (52.3%).
• Detroit has covered the spread in a lower percentage of its home games than road games. It has covered 15 times in 32 games when playing at home, and it has covered 18 times in 32 games when playing on the road.
• The Pistons have gone over the total less consistently when playing at home, hitting the over in 14 of 32 home matchups (43.8%). In away games, they have hit the over in 15 of 32 games (46.9%).
• Against the spread, Philadelphia has had better results away (18-12-1) than at home (14-19-1).
• Looking at the over/under, 76ers games have gone over more often at home (18 of 34, 52.9%) than away (16 of 31, 51.6%).

Pistons Leaders

• Cade Cunningham's numbers on the season are 25.1 points, 5.6 boards and 9.9 assists per contest, shooting 45.9% from the floor and 35% from downtown, with an average of 2.1 made 3-pointers.
• Jalen Duren is averaging 18.6 points, 10.6 rebounds and 1.7 assists. At the other end, he averages 0.9 steals and 0.9 blocked shots.
• Duncan Robinson's numbers on the season are 11.9 points, 2.6 boards and 1.9 assists per game, shooting 43.6% from the field and 39.6% from downtown, with an average of 2.8 made 3-pointers.
• Tobias Harris' numbers on the season are 13.1 points, 5.1 rebounds and 2.2 assists per game, shooting 45.1% from the field and 33% from beyond the arc, with an average of 1.3 made 3-pointers.
• Isaiah Stewart's numbers on the season are 10 points, 5.1 rebounds and 1.2 assists per game, shooting 53.6% from the field.

76ers Leaders

• VJ Edgecombe averages 15.4 points, 5.5 rebounds and 3.9 assists. He is also sinking 42.8% of his shots from the floor and 35.8% from beyond the arc, with 2.1 triples per game.
• Quentin Grimes' numbers on the season are 13 points, 3.6 rebounds and 3.4 assists per contest. He is draining 44.7% of his shots from the floor and 33.8% from beyond the arc, with an average of 1.8 treys.
• Per game, Andre Drummond gets the 76ers 6.5 points, 8.4 rebounds and 1 assists, plus 0.6 steals and 0.8 blocks.
• The 76ers receive 8.1 points per game from Dominick Barlow, plus 4.6 rebounds and 1.1 assists.
• Per game, Adem Bona gets the 76ers 4.6 points, 4.3 boards and 0.4 assists, plus 0.4 steals and 1.2 blocks.

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