Pirates vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for April 1

Odds updated as of 8:13 p.m.

The MLB's Wednesday slate includes the Pittsburgh Pirates facing the Cincinnati Reds.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Pirates vs Reds Game Info

• Pittsburgh Pirates (1-3) vs. Cincinnati Reds (3-1)
• Date: Wednesday, April 1, 2026
• Time: 12:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and SportsNet PT

Pirates vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-156) | CIN: (+132)
• Spread: PIT: -1.5 (+112) | CIN: +1.5 (-134)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Pirates vs Reds Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 0-1, 67.50 ERA vs Andrew Abbott (Reds) - 0-0, 0.00 ERA

The Pirates will look to Paul Skenes against the Reds and Andrew Abbott. Skenes and his team failed to cover the spread in his only opportunity this season as a starter. Skenes has yet to start a game this season when his team was the moneyline favorite. Abbott has started just one game with a set spread, which the Reds failed to cover. The Reds were the moneyline underdog for one Abbott start this season -- they lost.

Pirates vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (53.5%)

Pirates vs Reds Moneyline

• Looking at the moneyline for Pirates-Reds, Pittsburgh is the favorite at -156, and Cincinnati is +132 playing at home.

Pirates vs Reds Spread

• The Reds are +1.5 on the run line against the Pirates. The Reds are -134 to cover, and the Pirates are +112.

Pirates vs Reds Over/Under

• The over/under for the Pirates versus Reds game on April 1 has been set at 7.5, with -110 odds on the over and -110 odds on the under.

Bet on Pittsburgh Pirates vs. Cincinnati Reds on FanDuel today!

Pirates vs Reds Betting Trends

• The Pirates were victorious in 21, or 51.2%, of the 41 contests they were chosen as favorites last season.
• Last year, Pittsburgh won five of nine games when listed as at least -156 on the moneyline.
• The Pirates and their opponents hit the over in 58 of their 153 games with a total last season.
• The Reds compiled a 42-45 record in games last season when they were the underdog on the moneyline (winning 48.3% of those games).
• In games it played as a moneyline underdog with odds of +132 or longer last year, Cincinnati went 14-15 (48.3%).
• The Reds combined with their opponents to go over the total 61 times last season for a 61-84-10 record against the over/under.

Pirates Player Leaders

• Last season, Brandon Lowe had 130 base hits, batting .256 with 50 extra-base hits.
• Ryan O'Hearn finished with an OBP of .366 while batting .281 with 67 runs scored.
• Marcell Ozuna ended his last campaign with 113 hits, an OBP of .355, plus a slugging percentage of .400.
• Bryan Reynolds hit 16 homers while driving in 73 runs.

Reds Player Leaders

• Elly De La Cruz accumulated a .440 slugging percentage and a .264 batting average last year.
• Eugenio Suarez racked up 134 hits with a .228 batting average.
• TJ Friedl had a .364 on-base percentage while batting .261 last season.
• Spencer Steer hit .238 with 21 doubles, two triples, 21 home runs and 51 walks.

Pirates vs Reds Head to Head

• 3/30/2026: 2-0 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/24/2025: 4-3 PIT (Favorite: Reds, Spread: -1.5, Total: 7, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 9/23/2025: 4-2 PIT (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/10/2025: 14-8 CIN (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/9/2025: 2-1 CIN (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/8/2025: 3-2 PIT (Favorite: Reds, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/7/2025: 7-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/21/2025: 3-1 PIT (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/20/2025: 1-0 PIT (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/19/2025: 7-1 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!