Phillies vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 16

Odds updated as of 1:12 a.m.

The Philadelphia Phillies are among the MLB teams playing on Wednesday, up against the Washington Nationals.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Phillies vs Nationals Game Info

• Philadelphia Phillies (83-68) vs. Washington Nationals (71-81)
• Date: Wednesday, September 16, 2026
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: Nationals.TV and NBCS-PH

Phillies vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-196) | WSH: (+164)
• Spread: PHI: -1.5 (-110) | WSH: +1.5 (-110)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Phillies vs Nationals Probable Starting Pitchers

Probable Pitchers: Zack Wheeler (Phillies) - 12-5, 3.14 ERA vs Jared Simpson (Nationals) - 1-0, 6.75 ERA

The Phillies will look to Zack Wheeler (12-5) against the Nationals and Jared Simpson (1-0). Wheeler and his team are 13-9-0 ATS this season when he starts. Wheeler's team is 13-4 this season when he starts and they are the moneyline favorite. Simpson did not pitch as a moneyline underdog a season ago.

Phillies vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Nationals win (56.2%)

Phillies vs Nationals Moneyline

• Looking at the moneyline for Phillies-Nationals, Philadelphia is the favorite at -196, and Washington is +164 playing at home.

Phillies vs Nationals Spread

• The Phillies are at the Nationals and are favored by 1.5 runs (-110 to cover) on the runline. Washington is -110 to cover.

Phillies vs Nationals Over/Under

• The Phillies-Nationals game on Sept. 16 has been given an over/under of 8.5 runs. The over is set at -115 and the under at -105.

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Phillies vs Nationals Betting Trends

• The Phillies have been favorites in 111 games this season and have come away with the win 71 times (64%) in those contests.
• This season Philadelphia has come away with a win 17 times in 22 chances when named as a favorite of at least -196 on the moneyline.
• Contests with the Phillies have gone over the total set by oddsmakers in 70 of 146 chances this season.
• The Phillies have posted a record of 61-85-0 against the spread this season.
• The Nationals are 49-65 in games they were the underdog on the moneyline (winning 43% of those games).
• When it has played as a moneyline underdog with odds of +164 or longer, Washington has a 6-12 record (winning just 33.3% of its games).
• In the 148 games oddsmakers have set an over/under for the Nationals, they have combined with opponents to go over the total 78 times (78-64-6).
• The Nationals have put together an 81-67-0 record ATS this season (covering 54.7% of the time).

Phillies Player Leaders

• Bryce Harper leads Philadelphia with an OBP of .384 this season while batting .270 with 102 walks and 88 runs scored. He has a slugging percentage of .497.
• Among qualifying batters in baseball, his batting average ranks 44th, his on-base percentage ranks sixth, and he is 15th in slugging.
• Luis Arraez has hit six homers this season while driving in 60 runs. He's batting .315 this season and slugging .428 with an on-base percentage of .348.
• Among qualifying hitters, his batting average ranks him first, his on-base percentage 44th, and his slugging percentage 66th.
• Kyle Schwarber has 130 hits and is batting .239 this season.
• Schwarber has recorded at least one base hit in two games in a row. During his last five outings he is batting .158 with a home run, three walks and three RBIs.
• Trea Turner has been key for Philadelphia with 145 hits, an OBP of .293 plus a slugging percentage of .384.
• Turner enters this matchup on a three-game hitting streak. In his last five games he is hitting .200 with a walk and an RBI.

Nationals Player Leaders

• C.J. Abrams has a .494 slugging percentage, which paces the Nationals. He's batting .264 with an on-base percentage of .339.
• He ranks 57th in batting average, 58th in on-base percentage and 17th in slugging percentage among all qualified hitters in the big leagues.
• Abrams heads into this game on a three-game hitting streak. During his last five outings he is batting .300 with three doubles, a walk and an RBI.
• James Wood has 127 hits with a .394 on-base percentage to pace his team in both. He has a batting average of .267 while slugging .522.
• He ranks 51st in batting average, second in on-base percentage and eighth in slugging percentage in the majors.
• Daylen Lile is hitting .250 with 27 doubles, eight triples, 21 home runs and 39 walks.
• Jacob Young is hitting .247 with 20 doubles, three triples, 10 home runs and 32 walks.

Phillies vs Nationals Head to Head

• 9/15/2026: 6-3 WSH (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 8/6/2026: 7-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -320, Underdog Moneyline: +280)
• 8/5/2026: 10-4 WSH (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -198, Underdog Moneyline: +182)
• 8/4/2026: 5-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -300, Underdog Moneyline: +260)
• 8/3/2026: 6-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +142)
• 6/25/2026: 10-5 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/24/2026: 5-4 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/23/2026: 14-9 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 4/1/2026: 6-5 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 3/31/2026: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -188, Underdog Moneyline: +158)

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