Phillies vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 16

Odds updated as of 6:13 p.m.

In MLB action on Wednesday, the Philadelphia Phillies play the Washington Nationals.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Phillies vs Nationals Game Info

• Philadelphia Phillies (83-68) vs. Washington Nationals (71-81)
• Date: Wednesday, September 16, 2026
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: Nationals.TV and NBCS-PH

Phillies vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-196) | WSH: (+164)
• Spread: PHI: -1.5 (-120) | WSH: +1.5 (+100)
• Total: 8.5 -- Over: (-140) | Under: (+114)

Phillies vs Nationals Probable Starting Pitchers

Probable Pitchers: Zack Wheeler (Phillies) - 12-5, 3.14 ERA vs Jared Simpson (Nationals) - 1-0, 6.75 ERA

The probable pitchers are Zack Wheeler (12-5) for the Phillies and Jared Simpson (1-0) for the Nationals. Wheeler's team is 13-9-0 against the spread this season in his starts. Wheeler's team has won 76.5% of his starts when they are favored on the moneyline (13-4). Simpson and his team were underdogs on the moneyline each game he pitched a season ago.

Phillies vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (55.2%)

Phillies vs Nationals Moneyline

• The moneyline numbers for Phillies vs. Nationals reveal Philadelphia as the favorite (-196) and Washington as the underdog (+164) despite being the home team.

Phillies vs Nationals Spread

• The Nationals are at +1.5 on the runline against the Phillies. The Nationals are +100 to cover the spread, and the Phillies are -120.

Phillies vs Nationals Over/Under

• Phillies versus Nationals, on Sept. 16, has an over/under of 8.5, with the over being -140 and the under +114.

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Phillies vs Nationals Betting Trends

• The Phillies have won in 71, or 64%, of the 111 contests they have been named as odds-on favorites in this year.
• Philadelphia has a record of 17-5 when favored by -196 or more this year.
• The Phillies and their opponents have gone over in 70 of their 146 games with a total set by sportsbooks this season.
• The Phillies have posted a record of 61-85-0 against the spread this season.
• The Nationals have won 49 of the 114 games they were the underdog on the moneyline this season (43%).
• When playing as a moneyline underdog with odds of +164 or longer, Washington has a 6-12 record (winning only 33.3% of its games).
• The Nationals have played in 148 games with an over/under set, and have combined with opponents to go over the total 78 times (78-64-6).
• The Nationals are 81-67-0 against the spread this season.

Phillies Player Leaders

• Bryce Harper has 144 hits this season and a team-best OBP of .384. He has a .270 batting average and a slugging percentage of .497.
• Among qualified hitters in the majors, he ranks 45th in batting average, sixth in on-base percentage, and 15th in slugging.
• Luis Arraez leads Philadelphia in slugging percentage (.428) thanks to 45 extra-base hits. He's batting .315 with an on-base percentage of .348.
• He is first in batting average, 44th in on-base percentage and 66th in slugging in the majors.
• Kyle Schwarber leads Philadelphia with 130 hits. He is batting .239 this season and 63 of his hits have gone for extra bases.
• Schwarber has logged a hit or more in two games in a row. In his last five games he is hitting .158 with a home run, three walks and three RBIs.
• Trea Turner has been key for Philadelphia with 145 hits, an OBP of .293 plus a slugging percentage of .384.
• Turner has hit safely in three straight games. In his last five games he is batting .200 with a walk and an RBI.

Nationals Player Leaders

• C.J. Abrams has racked up a team-best .494 slugging percentage. He's batting .264 with an on-base percentage of .339.
• Including all qualified hitters in MLB, he is 57th in batting average, 58th in on-base percentage and 17th in slugging percentage.
• Abrams takes a three-game hitting streak into this matchup. In his last five games he is hitting .300 with three doubles, a walk and an RBI.
• James Wood's 127 hits and .394 on-base percentage both pace his team. He has a batting average of .267 while slugging .522.
• He ranks 51st in batting average, second in on-base percentage and eighth in slugging percentage in the big leagues.
• Daylen Lile is batting .250 with 27 doubles, eight triples, 21 home runs and 39 walks.
• Jacob Young is hitting .247 with 20 doubles, three triples, 10 home runs and 32 walks.

Phillies vs Nationals Head to Head

• 9/15/2026: 6-3 WSH (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 8/6/2026: 7-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -320, Underdog Moneyline: +280)
• 8/5/2026: 10-4 WSH (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -198, Underdog Moneyline: +182)
• 8/4/2026: 5-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -300, Underdog Moneyline: +260)
• 8/3/2026: 6-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +142)
• 6/25/2026: 10-5 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/24/2026: 5-4 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/23/2026: 14-9 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 4/1/2026: 6-5 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 3/31/2026: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -188, Underdog Moneyline: +158)

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