Phillies vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for April 6

Odds updated as of 6:13 a.m.

The MLB slate on Monday includes the Philadelphia Phillies taking on the San Francisco Giants.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Phillies vs Giants Game Info

• Philadelphia Phillies (5-4) vs. San Francisco Giants (3-7)
• Date: Monday, April 6, 2026
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and NBCS-PH+

Phillies vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-118) | SF: (+100)
• Spread: PHI: -1.5 (+152) | SF: +1.5 (-184)
• Total: 8 -- Over: (-105) | Under: (-115)

Phillies vs Giants Probable Starting Pitchers

Probable Pitchers: Andrew Painter (Phillies) - 1-0, 1.69 ERA vs Adrian Houser (Giants) - 0-1, 1.69 ERA

This contest's pitching matchup is set, as the Phillies will send Andrew Painter (1-0) to the mound, while Adrian Houser (0-1) will take the ball for the Giants. Painter and his team failed to cover the spread in his only opportunity this season as a starter. Painter's team won his only start as a favorite this season. Houser has started only one game with a set spread, which the Giants failed to cover. The Giants were the moneyline underdog for one Houser start this season -- they lost.

Phillies vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (51%)

Phillies vs Giants Moneyline

• The moneyline numbers for Phillies vs. Giants reveal Philadelphia as the favorite (-118) and San Francisco as the underdog (+100) despite being the home team.

Phillies vs Giants Spread

• The Phillies are 1.5-run road favorites on the runline against the Giants. The Phillies are +152 to cover, and the Giants are -184.

Phillies vs Giants Over/Under

• A combined run total of 8 has been set for Phillies-Giants on April 6, with the over at -105 and the under at -115.

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Phillies vs Giants Betting Trends

• The Phillies have been victorious in five of the nine contests they have been chosen as favorites in this season.
• This year Philadelphia has won five of nine games when listed as at least -118 on the moneyline.
• The Phillies' games have gone over the total in five of their nine opportunities.
• The Phillies have posted a record of 2-7-0 against the spread this season.
• The Giants have been the underdog on the moneyline seven total times this season. They've finished 2-5 in those games.
• San Francisco has a 1-5 record (winning only 16.7% of its games) when it has played as a moneyline underdog of +100 or longer.
• The Giants have played in 10 games with a set over/under, and have combined with their opponents to go over the total four times (4-3-3).
• The Giants have a 2-8-0 record against the spread this season (covering only 20% of the time).

Phillies Player Leaders

• Brandon Marsh is batting .303 with three doubles, a home run and two walks. He has an on-base percentage of .343 while slugging .485.
• Among qualifying batters in MLB, his batting average ranks 36th, his on-base percentage ranks 75th, and he is 49th in slugging.
• Marsh will look for his seventh straight game with a hit in this contest. In his last nine games he is hitting .303 with three doubles, a home run, two walks and five RBIs.
• Trea Turner leads Philadelphia in slugging percentage (.395) thanks to four extra-base hits. He's batting .289 with an on-base percentage of .341.
• Among qualifying batters, he is 50th in batting average, 78th in on-base percentage and 86th in slugging percentage.
• Turner takes a six-game streak with at least one hit into this matchup. During his last nine outings he is batting .289 with four doubles, three walks and two RBIs.
• Kyle Schwarber leads Philadelphia with six hits and an OBP of .366 this season.
• Alec Bohm is batting .176 with a .282 OBP and seven RBI for Philadelphia this season.
• Bohm brings a three-game hitting streak into this matchup. In his last five games he is hitting .200 with two walks and three RBIs.

Giants Player Leaders

• Matt Chapman has racked up nine hits with a .310 on-base percentage, leading the Giants in both statistics. He's batting .237 and slugging .368.
• Including all qualifying hitters in the majors, his batting average places him 89th, his on-base percentage is 106th, and he is 100th in slugging.
• Luis Arraez is slugging .350 to lead his team. He has a batting average of .275 with an on-base percentage of .286.
• His batting average is 59th among all qualified players, his on-base percentage is 132nd, and he is 112th in slugging.
• Jung Hoo Lee has three doubles and five walks while batting .152.
• Rafael Devers has a double, a home run and four walks while hitting .211.

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