Phillies vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 10:11 p.m.

On Thursday in MLB, the Philadelphia Phillies are up against the Chicago Cubs.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Cubs Game Info

• Philadelphia Phillies (8-15) vs. Chicago Cubs (14-9)
• Date: Thursday, April 23, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and NBCS-PH

Phillies vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-124) | CHC: (+106)
• Spread: PHI: -1.5 (+130) | CHC: +1.5 (-156)
• Total: 9 -- Over: (-105) | Under: (-115)

Phillies vs Cubs Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 2-2, 1.59 ERA vs Edward Cabrera (Cubs) - 2-0, 2.38 ERA

The Phillies will look to Cristopher Sanchez (2-2) against the Cubs and Edward Cabrera (2-0). Sanchez and his team are 2-3-0 ATS this season when he starts. Sanchez's team has won 60% of his starts when they are favored on the moneyline (3-2). The Cubs have a 2-2-0 record against the spread in Cabrera's starts. The Cubs have not been the underdog on the moneyline when Cabrera starts this season.

Phillies vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (52.7%)

Phillies vs Cubs Moneyline

• Looking at the moneyline for Cubs-Phillies, Chicago is the underdog at +106, and Philadelphia is -124 playing on the road.

Phillies vs Cubs Spread

• The Cubs are +1.5 on the run line against the Phillies. The Cubs are -156 to cover, and the Phillies are +130.

Phillies vs Cubs Over/Under

• Phillies versus Cubs on April 23 has an over/under of 9 runs, with the odds on the over -105 and the under set at -115.

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Phillies vs Cubs Betting Trends

• The Phillies have won in eight, or 42.1%, of the 19 contests they have been named as odds-on favorites in this year.
• This season Philadelphia has been victorious seven times in 18 chances when named as a favorite of at least -124 on the moneyline.
• The Phillies and their opponents have gone over the total this season in 11 of their 23 opportunities.
• The Phillies are 4-19-0 against the spread in their 23 games that had a posted line this season.
• The Cubs are 4-2 in games they were the underdog on the moneyline (winning 66.7% of those games).
• In games it has played as a moneyline underdog with odds of +106 or longer, Chicago has gone 2-1 (66.7%).
• In the 23 games bookmakers have set an over/under for the Cubs, they have combined with opponents to go over the total 13 times (13-10-0).
• The Cubs are 11-12-0 against the spread this season.

Phillies Player Leaders

• Bryce Harper leads Philadelphia with an OBP of .365, plus a team-best slugging percentage of .536. He's batting .274 on the season.
• Among all qualified hitters in the majors, his batting average ranks 49th, his on-base percentage ranks 41st, and he is 21st in slugging.
• Harper has recorded a base hit in three straight games. During his last five outings he is batting .333 with a triple, a home run, two walks and two RBIs.
• Kyle Schwarber has 18 hits, which is best among Philadelphia batters this season. He's batting .217 with 12 extra-base hits. He's also slugging .554 with an on-base percentage of .363.
• Among qualifying hitters, his batting average places him 137th, his on-base percentage 45th, and his slugging percentage 18th.
• Trea Turner has collected 22 base hits, an OBP of .294 and a slugging percentage of .340 this season.
• Brandon Marsh is batting .276 with a .300 OBP and 11 RBI for Philadelphia this season.
• Marsh enters this game on a two-game hitting streak. In his last five games he is hitting .176 with .

Cubs Player Leaders

• Nico Hoerner has a team-high OBP (.402) and slugging percentage (.533), and paces the Cubs in hits (30, while batting .326).
• Including all the qualified hitters in MLB, his batting average ranks sixth, his on-base percentage is 14th, and he is 22nd in slugging.
• Hoerner takes a three-game hitting streak into this matchup. During his last five outings he is hitting .333 with two home runs, a walk and four RBIs.
• Dansby Swanson has a double, five home runs and 18 walks while batting .187. He's slugging .400 with an on-base percentage of .337.
• His batting average ranks 162nd among all qualified players, his on-base percentage ranks 79th, and he is 82nd in slugging.
• Ian Happ is hitting .244 with four doubles, six home runs and 15 walks.
• Carson Kelly is batting .310 with three doubles, two home runs and 11 walks.

Phillies vs Cubs Head to Head

• 4/21/2026: 7-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/20/2026: 5-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/15/2026: 11-2 CHC (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 4/14/2026: 10-4 CHC (Favorite: Phillies, Spread: -1.5, Total: 10, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 4/13/2026: 13-7 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 6/11/2025: 7-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/10/2025: 8-4 CHC (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/9/2025: 4-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/27/2025: 3-1 PHI (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/26/2025: 10-4 PHI (Favorite: Phillies, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)

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