Padres vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 29

Odds updated as of 5:18 a.m.
In MLB action on Friday, the San Diego Padres take on the Minnesota Twins.
We've got you covered, in terms of the vital information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.
Padres vs Twins Game Info
- San Diego Padres (75-59) vs. Minnesota Twins (60-73)
- Date: Friday, August 29, 2025
- Time: 8:10 p.m. ET
- Venue: Target Field -- Minneapolis, Minnesota
- Coverage: MNNT and SDPA
Padres vs Twins Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: SD: (-126) | MIN: (+108)
- Spread: SD: -1.5 (+134) | MIN: +1.5 (-162)
- Total: 8.5 -- Over: (-122) | Under: (-100)
Padres vs Twins Probable Starting Pitchers
Probable Pitchers: Nestor Cortes (Padres) - 2-2, 4.66 ERA vs Zebby Matthews (Twins) - 3-4, 5.30 ERA
This contest's pitching matchup is set, as the Padres will send Nestor Cortes (2-2) to the mound, while Zebby Matthews (3-4) will answer the bell for the Twins. Cortes and his team are 3-3-0 ATS this season when he starts. Cortes' team has a record of 2-1 this season when he starts and they are the favorite on the moneyline. The Twins have a 4-7-0 ATS record in Matthews' 11 starts that had a set spread. The Twins have been the underdog on the moneyline in four of Matthews' starts this season, and they went 2-2 in those games.
Padres vs Twins Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (53.7%)
Padres vs Twins Moneyline
- The moneyline numbers for Padres vs. Twins reveal San Diego as the favorite (-126) and Minnesota as the underdog (+108) despite being the home team.
Padres vs Twins Spread
- The Padres are at the Twins and are favored by 1.5 runs on the spread. The Padres are +134 to cover the runline, with the Twins being -162.
Padres vs Twins Over/Under
- The Padres-Twins game on Aug. 29 has been given an over/under of 8.5 runs. The over is set at -122 and the under at -100.
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Padres vs Twins Betting Trends
- The Padres have come away with 42 wins in the 67 contests they have been listed as the favorites in this season.
- This season San Diego has come away with a win 37 times in 58 chances when named as a favorite of at least -126 on the moneyline.
- Contests with the Padres have gone over the total set by sportsbooks in 57 of 132 chances this season.
- The Padres are 74-58-0 against the spread in their 132 games with a line set by sportsbooks this season.
- The Twins have compiled an 18-31 record in games they were listed as the moneyline underdog (winning 36.7% of those games).
- Minnesota is 12-17 (winning 41.4% of its games) when it has played as a moneyline underdog of +108 or longer.
- The Twins have had an over/under set by oddsmakers 128 times, and have combined with opponents to go over the total in 58 of those games (58-63-7).
- The Twins have a 63-65-0 record against the spread this season (covering 49.2% of the time).
Padres Player Leaders
- Fernando Tatis Jr. is hitting .264 with 27 doubles, two triples, 18 home runs and 79 walks. He has an on-base percentage of .370 while slugging .434.
- He ranks 63rd in batting average, 14th in on-base percentage, and 77th in slugging among qualified hitters in baseball.
- Tatis has hit safely in three games in a row. During his last five outings he is hitting .200 with two doubles, a home run, three walks and three RBIs.
- Manny Machado leads San Diego in slugging percentage (.471) and total hits (149) this season. He's batting .288 with an on-base percentage of .348.
- He is 17th in batting average, 43rd in on-base percentage and 44th in slugging among qualifying hitters.
- Luis Arraez has collected 147 base hits, an OBP of .316 and a slugging percentage of .388 this season.
- Xander Bogaerts has 10 home runs, 49 RBI and a batting average of .262 this season.
- Bogaerts heads into this matchup on a three-game hitting streak. In his last five games he is batting .235 with a double, a walk and three RBIs.
Twins Player Leaders
- Byron Buxton has accumulated a slugging percentage of .539 and has 104 hits, both team-best numbers for the Twins. He's batting .269 and with an on-base percentage of .331.
- Including all the qualifying players in the majors, his batting average ranks 49th, his on-base percentage is 76th, and he is 10th in slugging.
- Trevor Larnach has 19 doubles, a triple, 16 home runs and 45 walks while hitting .242. He's slugging .405 with an on-base percentage of .318.
- Including all qualified players, his batting average puts him 114th, his on-base percentage is 99th, and he is 104th in slugging.
- Brooks Lee is batting .249 with 13 doubles, a triple, 14 home runs and 25 walks.
- Ryan Jeffers' .347 OBP paces his team.
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