Padres vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for April 27

Odds updated as of 4:20 p.m.

The San Diego Padres will take on the Tampa Bay Rays in MLB action on Sunday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Padres vs Rays Game Info

• San Diego Padres (17-10) vs. Tampa Bay Rays (13-14)
• Date: Sunday, April 27, 2025
• Time: 4:10 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and FDSSUN

Padres vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-142) | TB: (+120)
• Spread: SD: -1.5 (+158) | TB: +1.5 (-192)
• Total: 7 -- Over: (-105) | Under: (-115)

Padres vs Rays Probable Starting Pitchers

Probable Pitchers: Randy Vasquez (Padres) - 1-2, 3.97 ERA vs Zack Littell (Rays) - 0-5, 5.28 ERA

The Padres will give the ball to Randy Vasquez (1-2, 3.97 ERA), who is eyeing win No. 2 on the season, and the Rays will turn to Zack Littell (0-5, 5.28 ERA). Vasquez and his team have a record of 3-2-0 against the spread when he starts. This will be Vasquez's first start this season with his team as the moneyline favorite. In all of Littell's five starts that had a set spread, the Rays failed to cover. The Rays were named the moneyline underdog for two Littell starts this season -- they lost both.

Padres vs Rays Moneyline

• San Diego is a -142 favorite on the moneyline, while Tampa Bay is a +120 underdog on the road.

Padres vs Rays Spread

• The Padres are favored by 1.5 runs at home versus the Rays. The Padres are +158 to cover the spread, while the Rays are -192.

Padres vs Rays Over/Under

• Padres versus Rays, on April 27, has an over/under of 7, with the over being -105 and the under -115.

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Padres vs Rays Betting Trends

• The Padres have been favorites in 14 games this season and have come away with the win 10 times (71.4%) in those contests.
• This year San Diego has won seven of nine games when listed as at least -142 on the moneyline.
• Contests with the Padres have gone over the total set by bookmakers in 10 of 27 chances this season.
• The Padres have an against the spread mark of 15-12-0 in 27 games with a line this season.
• The Rays have won five of the 11 games they were listed as the moneyline underdog this season (45.5%).
• Tampa Bay has a 3-3 record (winning 50% of its games) when it has played as a moneyline underdog of +120 or longer.
• The Rays have had an over/under set by oddsmakers 27 times, and have combined with opponents to go over the total in 11 of those games (11-14-2).
• The Rays have a 12-15-0 record ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego in OBP (.412), slugging percentage (.634) and total hits (35) this season. He has a .347 batting average.
• Among qualifying hitters, he is fifth in batting average, his on-base percentage ranks ninth, and he is fourth in slugging.
• Tatis will look for his third straight game with a hit in this contest. In his last five games he is batting .300 with two doubles and two RBI.
• Manny Machado is hitting .280 with 10 doubles, two home runs and 10 walks. He's slugging .440 with an on-base percentage of .345.
• He ranks 40th in batting average, 56th in on-base percentage and 59th in slugging among qualified hitters.
• Machado enters this game looking to extend his two-game hit streak. In his last five games he is batting .167 with a double and a walk.
• Xander Bogaerts has collected 22 base hits, an OBP of .330 and a slugging percentage of .326 this season.
• Gavin Sheets is batting .276 with a .317 OBP and 12 RBI for San Diego this season.

Rays Player Leaders

• Jonathan Aranda has put up a team-best OBP (.419), and leads the Rays in hits (25). He's batting .321 and slugging.
• Including all the qualified hitters in the big leagues, his batting average is 13th, his on-base percentage ranks seventh, and he is ninth in slugging.
• Yandy (Fernandez) Diaz's .389 slugging percentage paces his team. He has a batting average of .248 with an on-base percentage of .281.
• He ranks 81st in batting average, 124th in on-base percentage and 92nd in slugging percentage in the big leagues.
• Junior Caminero is batting .248 with five doubles, five home runs and six walks.
• Kameron Misner is batting .333 with seven doubles, a triple, three home runs and five walks.

Padres vs Rays Head to Head

• 4/26/2025: 4-1 TB (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/25/2025: 1-0 TB (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/1/2024: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/31/2024: 11-4 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/30/2024: 13-5 SD (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/18/2023: 5-4 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/17/2023: 2-0 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/16/2023: 6-2 TB (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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