Padres vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for May 31

Odds updated as of 9:12 p.m.

MLB action on Saturday includes the San Diego Padres taking on the Pittsburgh Pirates.

We've got you covered, in terms of the vital information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Padres vs Pirates Game Info

• San Diego Padres (32-23) vs. Pittsburgh Pirates (21-37)
• Date: Saturday, May 31, 2025
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and SportsNet PT

Padres vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-240) | PIT: (+198)
• Spread: SD: -1.5 (-111) | PIT: +1.5 (-108)
• Total: 7.5 -- Over: (-124) | Under: (+102)

Padres vs Pirates Probable Starting Pitchers

Probable Pitchers: Dylan Cease (Padres) - 1-3, 4.58 ERA vs Bailey Falter (Pirates) - 3-3, 3.47 ERA

The probable starters are Dylan Cease (1-3) for the Padres and Bailey Falter (3-3) for the Pirates. Cease's team is 6-5-0 against the spread this season in his starts. Cease's team has been victorious in 71.4% of the games he's started as the moneyline favorite with a record of 5-2. The Pirates have a 6-4-0 ATS record in Falter's 10 starts with a set spread. The Pirates have been the moneyline underdog in eight of Falter's starts this season, and they went 4-4 in those matchups.

Padres vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (64.1%)

Padres vs Pirates Moneyline

• Looking at the moneyline for Pirates-Padres, Pittsburgh is the underdog at +198, and San Diego is -240 playing at home.

Padres vs Pirates Spread

• The Padres are favored by 1.5 runs at home versus the Pirates. The Padres are -111 to cover the spread, while the Pirates are -108.

Padres vs Pirates Over/Under

• The Padres-Pirates game on May 31 has been given an over/under of 7.5 runs. The over is set at -124 and the under at +102.

Bet on San Diego Padres vs. Pittsburgh Pirates on FanDuel today!

Padres vs Pirates Betting Trends

• The Padres have won in 19, or 63.3%, of the 30 contests they have been named as odds-on favorites in this year.
• This year San Diego has won two of three games when listed as at least -240 on the moneyline.
• The Padres and their opponents have gone over the total this season in 23 of their 54 opportunities.
• In 54 games with a line this season, the Padres have a mark of 28-26-0 against the spread.
• The Pirates have gone 15-25 in games they were the underdog on the moneyline (winning 37.5% of those games).
• Pittsburgh has a 2-4 record (winning just 33.3% of its games) when it has played as a moneyline underdog of +198 or longer.
• In the 56 games oddsmakers have set an over/under for the Pirates, they have combined with opponents to go over the total 22 times (22-31-3).
• The Pirates have covered 44.6% of their games this season, going 25-31-0 against the spread.

Padres Player Leaders

• Fernando Tatis Jr. is hitting .269 with seven doubles, a triple, 13 home runs and 22 walks. He has an on-base percentage of .339 while slugging .495.
• Among all qualifying batters, he ranks 56th in batting average, his on-base percentage ranks 61st, and he is 31st in slugging.
• Manny Machado leads the Padres with an OPS of .867. He has a slash line of .314/.382/.485 this season.
• Among qualifying hitters, his batting average ranks him 12th, his on-base percentage 22nd, and his slugging percentage 37th.
• Machado has picked up a hit in seven straight games. In his last 10 outings he is batting .300 with three doubles, three home runs, three walks and five RBIs.
• Luis Arraez has collected 57 base hits, an OBP of .322 and a slugging percentage of .416 this season.
• Arraez enters this game with three games in a row with at least one hit. During his last five outings he is batting .278 with two doubles, a walk and four RBIs.
• Gavin Sheets leads San Diego with 47 hits, batting .270 this season with 18 extra-base hits.

Pirates Player Leaders

• Oneil Cruz is leading the Pirates with 40 hits. He's batting .225 and slugging .478 with an on-base percentage of .346.
• Including all the qualified players in the big leagues, his batting average is 139th, his on-base percentage is 55th, and he is 42nd in slugging.
• Bryan Reynolds is slugging .370 to pace his team. He has a batting average of .228 with an on-base percentage of .298.
• Including all qualified hitters, he ranks 137th in batting average, 134th in on-base percentage and 126th in slugging percentage.
• Isiah Kiner-Falefa is batting .297 with eight doubles, a triple, a home run and nine walks.
• Andrew McCutchen's .364 on-base percentage leads his team.

Padres vs Pirates Head to Head

• 5/30/2025: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 5/4/2025: 4-0 SD (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/2/2025: 9-4 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/14/2024: 8-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/13/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 8/12/2024: 2-1 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/8/2024: 7-6 SD (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/7/2024: 9-8 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/6/2024: 6-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 7/26/2023: 3-2 PIT (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -188, Underdog Moneyline: +158)

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