Padres vs Mariners Prediction, Odds, Moneyline, Spread & Over/Under for April 15

Odds updated as of 9:11 p.m.

In MLB action on Wednesday, the San Diego Padres face the Seattle Mariners.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Padres vs Mariners Game Info

• San Diego Padres (11-6) vs. Seattle Mariners (8-10)
• Date: Wednesday, April 15, 2026
• Time: 9:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Mariners.TV

Padres vs Mariners Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-108) | SEA: (-108)
• Spread: SD: +1.5 (-178) | SEA: -1.5 (+146)
• Total: 8 -- Over: (-102) | Under: (-120)

Padres vs Mariners Probable Starting Pitchers

Probable Pitchers: Randy Vasquez (Padres) - 1-0, 1.02 ERA vs Emerson Hancock (Mariners) - 2-1, 2.04 ERA

The Padres will give the nod to Randy Vasquez (1-0) versus the Mariners and Emerson Hancock (2-1). Vasquez's team has covered the spread in each of the three opportunities this season. Vasquez's team won his only start as a favorite this season. The Mariners have a 2-1-0 ATS record in Hancock's three starts with a set spread. The Mariners have not been the underdog on the moneyline when Hancock starts this season.

Padres vs Mariners Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (50.3%)

Padres vs Mariners Moneyline

• San Diego is a -108 favorite on the moneyline, while Seattle is a -108 underdog on the road.

Padres vs Mariners Spread

Padres vs Mariners Over/Under

• The over/under for the Padres versus Mariners game on April 15 has been set at 8, with -102 odds on the over and -120 odds on the under.

Bet on San Diego Padres vs. Seattle Mariners on FanDuel today!

Padres vs Mariners Betting Trends

• The Padres have been victorious in six of the eight contests they have been chosen as favorites in this season.
• This year San Diego has won seven of nine games when listed as at least -108 on the moneyline.
• The Padres' games have gone over the total in eight of their 17 opportunities.
• In 17 games with a line this season, the Padres have a mark of 12-5-0 against the spread.
• The Mariners have gone 1-2 in games they were the underdog on the moneyline (winning 33.3% of those games).
• When it has played as a moneyline underdog with odds of -108 or longer, Seattle has a 1-2 record (winning just 33.3% of its games).
• The Mariners have had an over/under set by oddsmakers 18 times, and have combined with opponents to go over the total in eight of those games (8-10-0).
• The Mariners have a 7-11-0 record ATS this season.

Padres Player Leaders

• Jackson Merrill is batting .250 with four doubles, three home runs and six walks. He has an on-base percentage of .314 and a slugging percentage of .453.
• Among qualifying hitters in the majors, he ranks 84th in batting average, 115th in on-base percentage, and 64th in slugging.
• Merrill has recorded at least one hit in four straight games. In his last five games he is hitting .368 with two doubles, a home run, three walks and four RBIs.
• Ramon Laureano leads San Diego in slugging percentage (.567) and total hits (17) this season. He's batting .283 with an on-base percentage of .348.
• Among qualifying batters, he ranks 55th in batting average, 71st in on-base percentage and 16th in slugging percentage.
• Laureano brings a four-game streak with at least one hit into this one. In his last five games he is batting .400 with a double, a triple, two home runs, three walks and five RBIs.
• Xander Bogaerts has hit two homers with a team-high .397 SLG this season.
• Bogaerts takes a two-game hitting streak into this matchup. In his last five games he is hitting .350 with a home run, three walks and seven RBIs.
• Manny Machado leads San Diego in OBP (.368) this season, fueled by 10 hits.

Mariners Player Leaders

• Randy Arozarena has accumulated a team-high .381 slugging percentage. He's batting .286 with an on-base percentage of .408.
• He ranks 52nd in batting average, 15th in on-base percentage and 95th in slugging percentage among all qualified batters in the majors.
• Brendan Donovan's .417 on-base percentage leads his team. He has a batting average of .292 while slugging .542.
• Including all qualified hitters, his batting average puts him 43rd, his on-base percentage is 13th, and he is 27th in slugging.
• Cole Young has two doubles, a triple, two home runs and seven walks while hitting .230.
• Luke Raley's 16 hits pace his team.

Padres vs Mariners Head to Head

• 4/14/2026: 4-1 SD (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/27/2025: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/26/2025: 7-6 SD (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/25/2025: 9-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/18/2025: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/17/2025: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/10/2024: 7-3 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/10/2024: 2-0 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)

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