Odds updated as of 7:25 PM

The MLB's Friday schedule includes the San Diego Padres facing the San Francisco Giants.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Giants Game Info

• San Diego Padres (2-1) vs. San Francisco Giants (0-1)
• Date: Friday, March 29, 2024
• Time: 9:40 PM ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA

Padres vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-130) | SF: (+110)
• Spread: SD: -1.5 (+158) | SF: +1.5 (-192)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Padres vs Giants Probable Starting Pitchers

Probable Pitchers: Joe Musgrove (Padres) - 0-0, 16.88 ERA vs Kyle Harrison (Giants) - 0-0, 0.00 ERA

The Padres will give the nod to Joe Musgrove versus the Giants and Kyle Harrison. Musgrove helped his team cover the spread in his only opportunity this season as a starter. Musgrove has yet to start a game this season when his team was the moneyline favorite. Last season when Harrison pitched his team finished 2-5-0 against the spread. Harrison and his team lost all four games he pitched when they were moneyline underdogs a season ago.

Padres vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (64.7%)

Padres vs Giants Moneyline

• The moneyline numbers for Padres vs. Giants reveal San Diego as the favorite (-130) and San Francisco as the underdog (+110) on the road.

Padres vs Giants Spread

• The Padres are 1.5-run home favorites on the runline against the Giants. The Padres are +158 to cover, and the Giants are -192.

Padres vs Giants Over/Under

• Padres versus Giants, on March 29, has an over/under of 7.5, with the over being -118 and the under -104.

Bet on San Diego Padres vs. San Francisco Giants on FanDuel today!

Padres vs Giants Betting Trends

• The Padres were favorites in 117 games last season and came away with the win 68 times (58.1%) in those contests.
• Last season San Diego came away with a win 60 times in 95 chances when named as a favorite of at least -130 or shorter on the moneyline.
• The Padres and their opponents hit the over in 64 of their 158 games with a total last season.
• The Giants won 34 of the 74 games they were the underdog on the moneyline last season (45.9%).
• San Francisco went 18-30 in games it played as a moneyline underdog with odds of +110 or longer (37.5%).
• The Giants played in 160 games with a set over/under last season, and combined with their opponents to go over the total 67 times (67-89-4).

Padres Player Leaders

• Last season, Xander Bogaerts finished with a slugging percentage of .440, fueled by 52 extra-base hits.
• Fernando Tatis Jr. slashed .257/.322/.449 and finished with an OPS of .770.
• Last season, Manny Machado had 140 base hits, batting .258 with 51 extra-base hits.
• Ha-Seong Kim had 140 hits and an OBP of .351.

Giants Player Leaders

• Jorge Soler had 126 hits and a batting average of .250 a season ago.
• Wilmer Flores hit .284 with 22 doubles, 23 home runs and 41 walks.
• LaMonte Wade Jr had a .373 on-base percentage while batting .256 last season.
• Thairo Estrada slugged .416 while batting .271.

Padres vs Giants Head to Head

• 3/28/2024: 6-4 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/27/2023: 5-2 SD (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/26/2023: 4-0 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 9/25/2023: 2-1 SF (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 9/3/2023: 4-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/2/2023: 6-1 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 9/1/2023: 7-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/31/2023: 7-2 SF (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/30/2023: 6-4 SD (Favorite: Padres, Spread: -1.5, Total: 19.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 4/29/2023: 16-11 SD (Favorite: Padres, Spread: -1.5, Total: 15.5, Favorite Moneyline: -198, Underdog Moneyline: +166)

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