Ole Miss vs Tulane Prediction, Odds, Picks, Best Bets for 2025 CFP First Round

Saturday's slate in college football includes a matchup between the Ole Miss Rebels and the Tulane Green Wave.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

Ole Miss vs Tulane Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ole Miss: (-901) | Tulane: (+610)
• Spread: Ole Miss: -16.5 (-122) | Tulane: +16.5 (100)
• Total: 57.5 -- Over: (-115) | Under: (-105)

Ole Miss vs Tulane Betting Trends

• Ole Miss has beaten the spread seven times in 12 games.
• Ole Miss owns one win ATS (1-2) as a 16.5-point favorite or greater this year.
• This season, six of Ole Miss' 12 games have go over the point total.
• Tulane is 7-6-0 against the spread this year.
• This year, four of Tulane's 13 games have hit the over.

Ole Miss vs Tulane Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Rebels win (86.2%)

Ole Miss vs Tulane Point Spread

Ole Miss is favored by 16.5 points (-122 to cover) in this matchup. Tulane, the underdog, is +100.

Ole Miss vs Tulane Over/Under

Ole Miss versus Tulane, on Dec. 20, has an over/under of 57.5, with the over being -115 and the under -105.

Ole Miss vs Tulane Moneyline

Ole Miss is a -901 favorite on the moneyline, while Tulane is a +610 underdog.

Ole Miss vs. Tulane Points Insights

Ole Miss vs. Tulane Game Info

• Game day: Saturday, December 20, 2025
• Game time: 3:30 p.m. ET
• TV channel: TNT
• Location: Oxford, Mississippi
• Stadium: Vaught-Hemingway Stadium

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Check out even more in-depth Ole Miss vs. Tulane analysis on FanDuel Research.