Ohio State vs Ohio Prediction, Odds, Picks, Best Bets for Week 3 2025

NCAA football action on Saturday includes the Ohio State Buckeyes playing the Ohio Bobcats.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Ohio State vs Ohio Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ohio State: (-10000) | Ohio: (+2400)
• Spread: Ohio State: -29.5 (-110) | Ohio: +29.5 (-110)
• Total: 49.5 -- Over: (-115) | Under: (-105)

Ohio State vs Ohio Betting Trends

• Ohio State has covered the spread in every game this year.
• Ohio State has yet to lose ATS (1-0) as a 29.5-point favorite or greater this season.
• One of two Ohio State games have hit the over this year.
• Ohio is unbeaten against the spread this season.
• One Ohio game (out of two) has gone over the point total this year.

Ohio State vs Ohio Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Buckeyes win (90.3%)

Ohio State vs Ohio Point Spread

Ohio is listed as an underdog by 29.5 points (-110 odds), and Ohio State, the favorite, is -110 to cover.

Ohio State vs Ohio Over/Under

An over/under of 49.5 has been set for Ohio State-Ohio on Sept. 13, with the over being -115 and the under -105.

Ohio State vs Ohio Moneyline

Looking at the moneyline for Ohio State-Ohio, Ohio State is the favorite at -10000, and Ohio is +2400.

Ohio State vs. Ohio Points Insights

Ohio State vs. Ohio Game Info

• Game day: Saturday, September 13, 2025
• Game time: 7 p.m. ET
• TV channel: Peacock
• Location: Columbus, Ohio
• Stadium: Ohio Stadium

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Check out even more in-depth Ohio State vs. Ohio analysis on FanDuel Research.