Ohio State vs Michigan Prediction, Odds, Picks, Best Bets for Week 14 2025

The college football schedule on Saturday includes the Ohio State Buckeyes taking on the Michigan Wolverines.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Ohio State vs Michigan Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ohio State: (-375) | Michigan: (+300)
• Spread: Ohio State: -10.5 (100) | Michigan: +10.5 (-122)
• Total: 43.5 -- Over: (-115) | Under: (-105)

Ohio State vs Michigan Betting Trends

• Against the spread, Ohio State is 9-2-0 this season.
• Against the spread as 10.5-point or better favorites, Ohio State is 7-2.
• There have been four Ohio State games (of 11) that went over the total this year.
• Michigan is 4-7-0 against the spread this year.
• Michigan has played 11 games this year, and six of them have gone over the total.

Ohio State vs Michigan Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Buckeyes win (61.6%)

Ohio State vs Michigan Point Spread

Michigan is a 10.5-point underdog against Ohio State. Michigan is -122 to cover the spread, and Ohio State is +100.

Ohio State vs Michigan Over/Under

A combined point total of 43.5 has been set for Ohio State-Michigan on Nov. 29, with the over at -115 and the under at -105.

Ohio State vs Michigan Moneyline

Ohio State is a -375 favorite on the moneyline, while Michigan is a +300 underdog.

Ohio State vs. Michigan Points Insights

Ohio State vs. Michigan Game Info

• Game day: Saturday, November 29, 2025
• Game time: 12 p.m. ET
• TV channel: FOX
• Location: Ann Arbor, Michigan
• Stadium: Michigan Stadium

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Check out even more in-depth Ohio State vs. Michigan analysis on FanDuel Research.