Notre Dame vs Clemson Prediction, Odds, & Betting Trends for College Football Week 10 Game

The Saturday slate in college football includes a matchup between the Notre Dame Fighting Irish and the Clemson Tigers.

We've got you covered, in terms of the vital info about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Notre Dame vs Clemson Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Notre Dame: (-170) | Clemson: (+140)
• Spread: Notre Dame: -3.5 (-105) | Clemson: +3.5 (-115)
• Total: 43.5 -- Over: (-110) | Under: (-110)

Notre Dame vs Clemson Betting Trends

• Notre Dame is 7-2-0 against the spread this year.
• This season, Notre Dame is 5-2 as 3.5-point or better favorites.
• Notre Dame has played nine games this season, and five of them have hit the over.
• Clemson has posted two wins against the spread this year.
• Two Clemson games (of seven) have hit the over this season.

Notre Dame vs Clemson Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Fighting Irish win (67.4%)

Notre Dame vs Clemson Point Spread

Notre Dame is a 3.5-point favorite against Clemson. Notre Dame is -105 to cover the spread, and Clemson is -115.

Notre Dame vs Clemson Over/Under

An over/under of 43.5 has been set for Notre Dame-Clemson on November 4, with the over being -110 and the under -110.

Notre Dame vs Clemson Moneyline

Notre Dame is a -170 favorite on the moneyline, while Clemson is a +140 underdog.

Notre Dame vs. Clemson Points Insights

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Check out even more in-depth Notre Dame vs. Clemson analysis on FanDuel Research.