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Los Angeles Chargers Vs. Buffalo Bills

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4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

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Type

Passing Yards

Receiving Yards

Rushing Yards

Passing Touchdowns

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

FOX

Los Angeles Chargers

0-0 | 0th in AFC West | 0th in AFC

SpreadMoneylineTotal

@

Buffalo Bills

0-0 | 0th in AFC East | 0th in AFC

SpreadMoneylineTotal

FOX

Highmark Stadium

Line Movement

These graphs show how the spread, moneyline, and total have shifted at FanDuel Sportsbook over time.

Spread

Chargers

Open: -

Bills

Open: -

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Moneyline

Chargers

Open: -

Bills

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Total

Over

Open: -

Under

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MLB Daily Dinger

Los Angeles Chargers

NameStatus

LBJunior Colson

QShoulder

Buffalo Bills

NameStatus

RBTy Johnson

QKnee

LBDemetrius Flannigan-Fowles

IRUndisclosed

WRTyrell Shavers

PUPKnee - ACL

OLBMichael Hoecht

QAchilles

LAC

BUF

-

Offensive EPA

-

-

Passing EPA

-

-

Rushing EPA

-

-

Defensive EPA

-

-

Def Pass EPA

-

-

Def Rush EPA

-

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Los Angeles Chargers Vs. Buffalo Bills Odds, Betting Lines, Score & Stats (September 27, 2026) | FanDuel Research

Los Angeles Chargers

QBJustin Herbert

18.4 Points

RBOmarion Hampton

11.8 Points

WRLadd McConkey

9.5 Points

WRQuentin Johnston

8.3 Points

Buffalo Bills

20.5 Points

14.9 Points

WRKhalil Shakir

7.7 Points

7.5 Points

NFL

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Los Angeles Chargers

DateOpponentResultSpread

Buffalo Bills

DateOpponentResultSpread