Menu

FanDuel Research Sportsbook Fantasy Casino Racing FanDuel TV Free2Play

Explore NFL

Home
News
Odds
Fantasy Football
Player News
NFL Picks
Player Prop Bets
Projections
Scores/Schedule
Daily Fantasy
Teams
Rankings
Game Updates
Injuries
Transactions
Lineups
DFS Picks
Fantasy Football Predictions
NFL Predictions
NFL Draft
How to Bet on the NFL

Explore MLB

Home
News
Teams
Odds
Fantasy
Projections
Player News
Game Updates
Injuries
Lineups
Transactions
World Series
Player Prop Bets
MLB Predictions

Explore NCAAF

Home
News
Odds
College Football Picks
College Football Predictions
National Championship Odds
Heisman Odds
Fantasy College Football
How to Bet on CFB

Explore NBA

Home
News
Teams
Odds
Fantasy
Projections
Player News
Game Updates
Injuries
Lineups
Transactions
NBA Predictions
Player Prop Bets
Playoff Predictions

Explore NHL

Home
News
Odds
Fantasy
Projections
NHL Predictions
Player Prop Bets
Player News
Game Updates
Injuries
Lineups
Transactions

Explore FanDuel Promos

FanDuel Sportsbook Promos
FanDuel Sportsbook Welcome Offer

Explore Email Sign-Up

Sign up for the FanDuel Research daily email newsletter!

More

Horse Racing
Soccer
WNBA
NASCAR
UFC
Golf
NCAAB
Tennis
MMA
F1
Boxing
Casino
Canada
Sports Betting 101
TV & Podcasts

NFL
- Home
- News
- Odds
- Fantasy Football
- Player News
- Projections
- Player Prop Bets
- NFL Picks
- Scores/Schedule
- Daily Fantasy
- Teams
- Rankings
- Game Updates
- Injuries
- Transactions
- Lineups
- Fantasy Football Predictions
- DFS Picks
- NFL Predictions
- Super Bowl
- NFL Draft
- How to Bet on NFL
MLB
- Home
- News
- Teams
- Odds
- Fantasy
- Projections
- Player News
- Game Updates
- Injuries
- Lineups
- Transactions
- World Series
- Player Prop Bets
- Predictions
NCAAF
- Home
- News
- Odds
- College Football Picks
- College Football Predictions
- National Championship Odds
- Heisman Odds
- Fantasy College Football
- How to Bet on CFB
Horse Racing
- Home
- News
- Odds
- Upcoming Races
- Track List
- Consensus Picks
- Belmont Stakes Odds
- Belmont Stakes Betting
Soccer
- Home
- News
- Odds
- Fantasy
- Premier League Odds
- World Cup Picks & Predictions
NBA
- Home
- News
- Teams
- Odds
- Fantasy
- Projections
- Player News
- Game Updates
- Injuries
- Lineups
- Transactions
- Predictions
- Player Prop Bets
- Playoff Predictions
WNBA
- Home
- News
- Odds
- WNBA Predictions
Golf
- Home
- News
- Golfers
- Odds
- Fantasy
- Projections
NHL
- Home
- News
- Odds
- Fantasy
- Projections
- NHL Predictions
- Player Prop Bets
- Player News
- Game Updates
- Injuries
- Lineups
- Transactions
NCAAB
- Home
- March Madness
- News
- Teams
- Odds
- Fantasy
- NCAAB Predictions
Tennis
- Home
- News
- Odds
- Australian Open
NASCAR
- Home
- News
- Odds
UFC
- Home
- News
- Odds
Boxing
- News
- Odds
- Home
F1
- Home
- News
- Odds
Casino
- Home
- News
- Casino Games
- How To Play
MMA
- Home
- News
- Odds
Canada
- FanDuel Canada
FanDuel Sportsbook Promos
- Codes
TV & Podcasts
- TV & Podcasts
Sports Betting 101
Email Sign-Up

ABOUT
Support
About FanDuel
What's New on Sportsbook
Betting Guides
How It Works
Rules & Scoring
Responsible Play
Modern Slavery Statement
Legal Sports Betting Map
Affiliates
Sitemap

SPORTSBOOK ODDS
NFL Odds
Super Bowl Odds
NBA Odds
MLB Odds
College Football Odds
College Basketball Odds
March Madness Odds
NHL Odds
Golf Odds
The Masters Odds
UFC Odds
Soccer Odds
NASCAR Odds
World Series Odds
CFB Playoff National Championship Odds

FANDUEL SPORTS BETTING STATES
FanDuel Sportsbook AR
FanDuel Sportsbook AZ
FanDuel Sportsbook CA
FanDuel Sportsbook CO
FanDuel Sportsbook CT
FanDuel Sportsbook DC
FanDuel Sportsbook IA
FanDuel Sportsbook IL
FanDuel Sportsbook IN
FanDuel Sportsbook LA
FanDuel Sportsbook MA
FanDuel Sportsbook MI
FanDuel Sportsbook NC
FanDuel Sportsbook NJ
FanDuel Sportsbook NY
FanDuel Sportsbook OH
FanDuel Sportsbook PA
FanDuel Sportsbook TN
FanDuel Sportsbook VA
FanDuel Sportsbook VT
FanDuel Sportsbook WV

FANDUEL NEWS
NFL
NBA
College Basketball
NHL
UFC
Soccer
Casino

FANDUEL GROUP PRODUCTS
FanDuel Sportsbook
TVG
FanDuel Casino
FanDuel Racing
FanDuel Faceoff
FanDuel Predicts

FANTASY SPORTS
NFL
NHL
MLB
Soccer
CFB
Golf
Tennis
NASCAR
WNBA
CBB

FANDUEL APPS
Fantasy (iOS)
Sportsbook & Fantasy (Android)
Sportsbook (iOS)
Sportsbook (Android)

NFL SPORTSBOOK BETTING
2026 Best FanDuel Sportsbook Promos
NFL Betting
NFL Picks
2025 NFL Team Power Rankings
NFL Team Schedules & Odds

FANDUEL CASINO
Online Slots
New Casino Games
Blackjack Online
Live Dealer Casino
Online Roulette
Online Table Games
FanDuel Casino Promo Codes

FOLLOW FANDUEL
Facebook
Twitter
Instagram
YouTube
Snapchat

Careers
Governance
Trust & Safety
Bill of Rights
Privacy Policy
California Privacy Rights
Terms of Use
Your Privacy Choices
Modern Slavery Statement
Press & Media

© Betfair Interactive US LLC, 2026

Gambling Problem? Call One Eight Hundred G A M B L E R

or

. Call

or visit ccpg.org/chat (CT). Hope is here. GamblingHelpLineMA.org or call Eight Hundred Three Two Seven Five Zero Five Zero

for 24/7 support (MA). Visit www.mdgamblinghelp.org (MD). Call Eight Seven Seven Eight H O P E N Y

or text HOPENY (467369) (NY). 21+ (18+ D.C., WY) and present in select states (for KS, in affiliation with Kansas Star Casino). Call One Eight Seven Seven Seven Seven Zero Seven Eight Six Seven

(LA).

Persons under 21 are not permitted to engage in sports wagering. For customer support please contact us.

Detroit Lions Vs. Buffalo Bills Odds, Betting Lines, Score & Stats (September 17, 2026) | FanDuel Research

FanDuel Research>
NFL>
Matchups>
Detroit Lions Vs. Buffalo Bills

Featured Player Props

View all NFL Player Props

Popular Bets

Odds not available yet.

Check back closer to game time!

4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

Featured Promos

View all Promos

Top Projected Fantasy Performers

Injuries

Team Stats

View all Team Stats

Game Log

More NFL Games

Odds not available yet.

Check back closer to game time!

Type

Passing Yards

Receiving Yards

Rushing Yards

Passing Touchdowns

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Bet $5, Get $50 for 7 days

NFL Every Touchdown Pays

College Football Profit Boost

New User Bet & Get

Detroit Lions

16.9 Points

WRAmon-Ra St. Brown

15.7 Points

15.6 Points

9.4 Points

Buffalo Bills

21.8 Points

16.2 Points

8.9 Points

TEDalton Kincaid

8.1 Points

NFL

NFL Predictions: 4 Best Player Prop Bets for Today's 49ers vs Rams Game in Australia

NFL Predictions: 4 Best Player Prop Bets for Today's 49ers vs Rams Game in Australia

7h

Puka Nacua and Christian McCaffrey headline the best player props for the NFL's historic trip Down Under. 49ers vs Rams best player prop bets Thursday night.

3 Fantasy Football Sleepers for NFL Week 1

17h

3 Fantasy Football Sleepers for NFL Week 1

Rams vs. 49ers Prediction: 3 Best NFL Picks, Props for Thursday Night Football

9h

Rams vs. 49ers Prediction: 3 Best NFL Picks, Props for Thursday Night Football

Fantasy Football RB Rankings for Week 1: Top 50 Running Backs

22h

Fantasy Football RB Rankings for Week 1: Top 50 Running Backs

Fantasy Football Start/Sit Week 1: Who to Start and Sit This Week

18h

Fantasy Football Start/Sit Week 1: Who to Start and Sit This Week

Fantasy Football WR Rankings for Week 1: Top 50 Wide Receivers

1d

Fantasy Football WR Rankings for Week 1: Top 50 Wide Receivers

Fantasy Football: 3 Bold Predictions for NFL Week 1

18h

Fantasy Football: 3 Bold Predictions for NFL Week 1

Fantasy Football Waiver Wire: 10 Best Pickups Heading Into NFL Week 1

2d

Fantasy Football Waiver Wire: 10 Best Pickups Heading Into NFL Week 1

Fantasy Football TE Rankings for Week 1: Top 20 Tight Ends

1d

Fantasy Football TE Rankings for Week 1: Top 20 Tight Ends

Patriots vs. Seahawks Picks: 3 Best NFL Predictions, Player Props for Tonight

11h

Patriots vs. Seahawks Picks: 3 Best NFL Predictions, Player Props for Tonight

Patriots vs. Seahawks Prediction: 3 Best NFL Picks, Props for Today (Sept. 9)

22h

Patriots vs. Seahawks Prediction: 3 Best NFL Picks, Props for Today (Sept. 9)

DET

BUF

-

Offensive EPA

-

-

Passing EPA

-

-

Rushing EPA

-

-

Defensive EPA

-

-

Def Pass EPA

-

-

Def Rush EPA

-

Detroit Lions

DateOpponentResultSpread

Buffalo Bills

DateOpponentResultSpread

Amazon Prime Video

Detroit Lions

0-0 | 1st in NFC North | 4th in NFC

SpreadMoneylineTotal

@

Buffalo Bills

0-0 | 3rd in AFC East | 7th in AFC

SpreadMoneylineTotal

Prime

Highmark Stadium

Line Movement

These graphs show how the spread, moneyline, and total have shifted at FanDuel Sportsbook over time.

Spread

Lions

Open: +3.5

Bills

Open: -3.5

Moneyline

Lions

Open: +164

Bills

Open: -196

Total

Over

Open: 52.5

Under

Open: 52.5

Detroit Lions

NameStatus

LBDamone Clark

IRUndisclosed

DEPayton Turner

IRBack

RBIsiah Pacheco

IRBack

DBChristian Izien

QGroin

DLMekhi Wingo

QGroin

Buffalo Bills

NameStatus

RBTy Johnson

QLower Leg

DBJordan Hancock

QQuadriceps

DLT.J. Sanders

QKnee