Mariners vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for March 26

Odds updated as of 10:12 p.m.

MLB Opening Day on Thursday features the Seattle Mariners facing the Cleveland Guardians.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Mariners vs Guardians Game Info

• Seattle Mariners (0-0) vs. Cleveland Guardians (0-0)
• Date: Thursday, March 26, 2026
• Time: 10:10 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Mariners.TV and CleGuardians.TV

Mariners vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-188) | CLE: (+158)
• Spread: SEA: -1.5 (+120) | CLE: +1.5 (-144)
• Total: 6.5 -- Over: (-122) | Under: (+100)

Mariners vs Guardians Probable Starting Pitchers

Probable Pitchers: Logan Gilbert (Mariners) - 0-0, 0.00 ERA vs Tanner Bibee (Guardians) - 0-0, 0.00 ERA

The Mariners will call on Logan Gilbert versus the Guardians and Tanner Bibee. In 28 games he pitched with a spread last season, Gilbert and his team finished with an 11-17-0 record ATS. Gilbert appeared in 22 games last season as the moneyline favorite and his team finished with a record of 15-7 in those contests. Last season when Bibee pitched his team finished 20-12-0 against the spread. Bibee's team went 6-8 in games he pitched when they were the underdog on the moneyline a season ago.

Mariners vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (68.9%)

Mariners vs Guardians Moneyline

• Seattle is the favorite, -188 on the moneyline, while Cleveland is a +158 underdog on the road.

Mariners vs Guardians Spread

• The Mariners are hosting the Guardians and are favored by 1.5 runs on the spread. The Mariners are +120 to cover the runline, with the Guardians being -144.

Mariners vs Guardians Over/Under

• An over/under of 6.5 has been set for Mariners-Guardians on March 26, with the over being -122 and the under +100.

Bet on Seattle Mariners vs. Cleveland Guardians on FanDuel today!

Mariners vs Guardians Betting Trends

• The Mariners were chosen as favorites in 114 games last year and walked away with the win 66 times (57.9%) in those games.
• Last year, Seattle won 16 of 19 games when listed as at least -188 on the moneyline.
• The Mariners and their opponents hit the over in 91 of their 168 games with a total last season.
• The Guardians were the underdog on the moneyline 88 times last season. They finished 41-47 in those games.
• Cleveland went 4-7 in games it played as a moneyline underdog with odds of +158 or longer (36.4%).
• The Guardians played in 161 games with a set over/under last season, and combined with their opponents to go over the total 69 times (69-85-7).

Mariners Player Leaders

• Cal Raleigh had 147 hits and an OBP of .359 last season.
• Julio Rodriguez had an OPS of .798, fueled by an OBP of .324 and a slugging percentage of .474.
• Last season, Josh Naylor finished with 20 home runs, 92 RBI and a batting average of .295 last season.
• Randy Arozarena slashed .238/.334/.426 and finished with an OPS of .760.

Guardians Player Leaders

• Jose Ramirez accumulated an OBP of .360 with 168 hits last season.
• Steven Kwan had a .374 slugging percentage while batting .272.
• Kyle Manzardo hit .234 with 19 doubles, two triples, 27 home runs and 48 walks a season ago.
• Angel Martinez hit .224 with 23 doubles, two triples, 11 home runs and 23 walks.

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