Mariners vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for March 26

Odds updated as of 5:12 a.m.

MLB Opening Day on Thursday features the Seattle Mariners taking on the Cleveland Guardians.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Mariners vs Guardians Game Info

• Seattle Mariners (0-0) vs. Cleveland Guardians (0-0)
• Date: Thursday, March 26, 2026
• Time: 10:10 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: SEAM and CLEG

Mariners vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-188) | CLE: (+158)
• Spread: SEA: -1.5 (+125) | CLE: +1.5 (-150)
• Total: 6.5 -- Over: (-115) | Under: (-105)

Mariners vs Guardians Probable Starting Pitchers

Probable Pitchers: Logan Gilbert (Mariners) - 0-0, 0.00 ERA vs Tanner Bibee (Guardians) - 0-0, 0.00 ERA

The Mariners will give the nod to Logan Gilbert against the Guardians and Tanner Bibee. Gilbert and his team were 11-17-0 against the spread when he pitched last season. Gilbert and his team won as favorites in 68.2% of his 22 appearances last season with a moneyline. Last season when Bibee pitched his team finished 20-12-0 against the spread. Bibee and his team finished 6-8 in the 14 games he appeared in when they were the moneyline underdog a season ago.

Mariners vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (69.1%)

Mariners vs Guardians Moneyline

• Seattle is a -188 favorite on the moneyline, while Cleveland is a +158 underdog on the road.

Mariners vs Guardians Spread

• The Guardians are +1.5 on the spread (-150 to cover), and Seattle is +125 to cover the runline.

Mariners vs Guardians Over/Under

• The Mariners-Guardians contest on March 26 has been given an over/under of 6.5 runs. The over is set at -115 and the under at -105.

Bet on Seattle Mariners vs. Cleveland Guardians on FanDuel today!

Mariners vs Guardians Betting Trends

• The Mariners were favorites in 114 games last season and came away with the win 66 times (57.9%) in those contests.
• Last year, Seattle won 16 of 19 games when listed as at least -188 on the moneyline.
• The Mariners and their opponents hit the over in 91 of their 168 games with a total last season.
• The Guardians won 46.6% of the games last season they were the moneyline underdog (41-47).
• Cleveland went 4-7 when playing as a moneyline underdog with odds of +158 or longer (36.4%).
• The Guardians combined with their opponents to go over the total 69 times last season for a 69-85-7 record against the over/under.

Mariners Player Leaders

• Cal Raleigh had 147 hits and an OBP of .359 last season.
• Julio Rodriguez hit 32 homers while driving in 95 runs.
• Josh Naylor ended his last campaign with 160 hits, an OBP of .353, plus a slugging percentage of .462.
• Randy Arozarena slashed .238/.334/.426 and finished with an OPS of .760.

Guardians Player Leaders

• Jose Ramirez racked up an on-base percentage of .360 and had 168 hits last season.
• Steven Kwan slugged .374 while batting .272.
• Kyle Manzardo hit .234 with 19 doubles, two triples, 27 home runs and 48 walks a season ago.
• Angel Martinez hit .224 with 23 doubles, two triples, 11 home runs and 23 walks.

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