Mariners vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for June 22

Odds updated as of 2:11 p.m.

The Sunday slate in MLB includes a matchup between the Seattle Mariners and the Chicago Cubs.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this matchup.

Mariners vs Cubs Game Info

• Seattle Mariners (38-37) vs. Chicago Cubs (46-30)
• Date: Sunday, June 22, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and ROOT Sports NW

Mariners vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-130) | CHC: (+110)
• Spread: SEA: -1.5 (+115) | CHC: +1.5 (-138)
• Total: 11.5 -- Over: (-106) | Under: (-114)

Mariners vs Cubs Probable Starting Pitchers

Probable Pitchers: Logan Gilbert (Mariners) - 1-2, 2.55 ERA vs Colin Rea (Cubs) - 4-2, 3.84 ERA

The probable starters are Logan Gilbert (1-2) for the Mariners and Colin Rea (4-2) for the Cubs. Gilbert's team is 3-4-0 against the spread this season in his starts. Gilbert's team has won 57.1% of his starts when they are favored on the moneyline (4-3). The Cubs have a 6-4-0 record against the spread in Rea's starts. The Cubs have played when named the moneyline underdog for three of Rea's starts this season, and they won every game.

Mariners vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (53.8%)

Mariners vs Cubs Moneyline

• Chicago is the underdog, +110 on the moneyline, while Seattle is a -130 favorite despite being on the road.

Mariners vs Cubs Spread

• The Mariners are at the Cubs and are favored by 1.5 runs on the spread. The Mariners are +115 to cover the runline, with the Cubs being -138.

Mariners vs Cubs Over/Under

• The over/under for Mariners-Cubs on June 22 is 11.5. The over is -106, and the under is -114.

Bet on Seattle Mariners vs. Chicago Cubs on FanDuel today!

Mariners vs Cubs Betting Trends

• The Mariners have been chosen as favorites in 46 games this year and have walked away with the win 24 times (52.2%) in those games.
• This year Seattle has won 19 of 35 games when listed as at least -130 on the moneyline.
• Contests with the Mariners have gone over the total set by bookmakers in 39 of 74 chances this season.
• The Mariners have posted a record of 32-42-0 against the spread this season.
• The Cubs have won nine of the 23 games they were the underdog on the moneyline this season (39.1%).
• When it has played as a moneyline underdog with odds of +110 or longer, Chicago has a 3-7 record (winning only 30% of its games).
• The Cubs have played in 74 games with an over/under set, and have combined with their opponents to go over the total 39 times (39-31-4).
• The Cubs have gone 38-36-0 against the spread this season.

Mariners Player Leaders

• Cal Raleigh has 75 hits, which is tops among Seattle hitters this season, while batting .272 with 44 extra-base hits. He has an on-base percentage of .377 and a slugging percentage of .649.
• Among the qualifying hitters in MLB, his batting average ranks 46th, his on-base percentage ranks 21st, and he is second in slugging.
• Raleigh has recorded a base hit in four straight games. In his last five games he is hitting .381 with two doubles, four home runs, a walk and 10 RBIs.
• Julio Rodriguez has an OPS of .721, fueled by an OBP of .316 and a team-best slugging percentage of .405 this season. He's batting .253.
• He ranks 90th in batting average, 106th in on-base percentage and 105th in slugging in the major leagues.
• Rodriguez brings a two-game streak with at least one hit into this one. In his last five games he is hitting .150 with a double and two walks.
• J.P. Crawford leads Seattle with an OBP of .408 this season while batting .290 with 50 walks and 33 runs scored.
• Jorge Polanco is batting .258 with a .307 OBP and 36 RBI for Seattle this season.

Cubs Player Leaders

• Kyle Tucker has put up a .395 on-base percentage and a .520 slugging percentage, both team-high averages for the Cubs. He's batting .283.
• Including all qualified players in the big leagues, he is 30th in batting average, sixth in on-base percentage and 15th in slugging percentage.
• Pete Crow-Armstrong leads his team with 79 hits and has a club-high .563 slugging percentage. He has a batting average of .270 with an on-base percentage of .308.
• His batting average is 50th among all qualified players, his on-base percentage is 117th, and he is seventh in slugging.
• Seiya Suzuki is hitting .253 with 19 doubles, two triples, 18 home runs and 26 walks.
• Nico Hoerner paces his team with a .353 slugging percentage.

Mariners vs Cubs Head to Head

• 6/21/2025: 10-7 CHC (Favorite: Cubs, Spread: -1.5, Total: 12.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 6/20/2025: 9-4 SEA (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/14/2024: 3-2 CHC (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/13/2024: 4-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/12/2024: 4-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/12/2023: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 11, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/11/2023: 14-9 CHC (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/10/2023: 3-2 CHC (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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