Mariners vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for April 24

Odds updated as of 5:12 a.m.

The Seattle Mariners versus the St. Louis Cardinals is on the MLB schedule for Friday.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Mariners vs Cardinals Game Info

• Seattle Mariners (11-15) vs. St. Louis Cardinals (14-10)
• Date: Friday, April 24, 2026
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and Mariners.TV

Mariners vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-162) | STL: (+136)
• Spread: SEA: -1.5 (+105) | STL: +1.5 (-126)
• Total: 8 -- Over: (-105) | Under: (-115)

Mariners vs Cardinals Probable Starting Pitchers

Probable Pitchers: George Kirby (Mariners) - 3-2, 2.97 ERA vs Andre Pallante (Cardinals) - 2-1, 4.05 ERA

The Mariners will call on George Kirby (3-2) versus the Cardinals and Andre Pallante (2-1). Kirby's team is 3-2-0 against the spread in his starts this season. When Kirby starts a game and his team is the favorite on the moneyline, they have a record of 3-2. The Cardinals have a 2-2-0 record against the spread in Pallante's starts. The Cardinals are 2-1 in Pallante's three starts this season that they were the underdog on the moneyline.

Mariners vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (53.9%)

Mariners vs Cardinals Moneyline

• The moneyline numbers for Mariners vs. Cardinals reveal Seattle as the favorite (-162) and St. Louis as the underdog (+136) despite being the home team.

Mariners vs Cardinals Spread

• The Mariners are 1.5-run road favorites on the runline against the Cardinals. The Mariners are +105 to cover, and the Cardinals are -126.

Mariners vs Cardinals Over/Under

• An over/under of 8 has been set for Mariners-Cardinals on April 24, with the over being -105 and the under -115.

Bet on Seattle Mariners vs. St. Louis Cardinals on FanDuel today!

Mariners vs Cardinals Betting Trends

• The Mariners have been victorious in 10, or 45.5%, of the 22 contests they have been chosen as favorites in this season.
• This season Seattle has come away with a win five times in nine chances when named as a favorite of at least -162 on the moneyline.
• The Mariners' games have gone over the total in 12 of their 26 opportunities.
• The Mariners are 9-17-0 against the spread in their 26 games with a line set by sportsbooks this season.
• The Cardinals have won 57.1% of the games this season they were the moneyline underdog (12-9).
• When playing as a moneyline underdog with odds of +136 or longer, St. Louis has gone 1-2 (33.3%).
• The Cardinals have combined with opponents to hit the over on the total 13 times this season for a 13-10-1 record against the over/under.
• The Cardinals have put together a 13-11-0 record ATS this season.

Mariners Player Leaders

• Randy Arozarena leads Seattle in OBP (.385), slugging percentage (.419) and total hits (27) this season. He has a .290 batting average.
• Among all qualified hitters in the majors, he ranks 32nd in batting average, 22nd in on-base percentage, and 79th in slugging.
• Arozarena will look for his third straight game with a hit in this contest. In his last five games he is hitting .316 with two doubles, a home run and three RBIs.
• Cole Young has two doubles, a triple, two home runs and 11 walks. He's batting .233 and slugging .344 with an on-base percentage of .324.
• Among all qualified hitters, he ranks 116th in batting average, 109th in on-base percentage and 132nd in slugging percentage.
• Cal Raleigh has collected 20 base hits, an OBP of .281 and a slugging percentage of .386 this season.
• Raleigh has recorded at least one base hit in four straight games. During his last five outings he is hitting .333 with a double, three home runs, two walks and three RBIs.
• Luke Raley has five home runs, 13 RBI and a batting average of .292 this season.

Cardinals Player Leaders

• Jordan Walker has a slugging percentage of .607 and has 26 hits, both team-high numbers for the Cardinals. He's batting .292 and with an on-base percentage of .357.
• Including all the qualified players in the big leagues, his batting average is 29th, his on-base percentage ranks 54th, and he is fifth in slugging.
• Alec Burleson is batting .278 with six doubles, three home runs and 12 walks. He's slugging .444 with an on-base percentage of .359.
• His batting average ranks 47th among all qualified players, his on-base percentage ranks 51st, and he is 57th in slugging.
• Ivan Herrera a has .387 on-base percentage to pace the Cardinals.
• JJ Wetherholt has two doubles, three home runs and 15 walks while batting .218.

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