Louisville vs Virginia College Basketball Prediction, Odds, Picks, Best Bets for Jan. 13

The Virginia Cavaliers (14-2, 3-1 ACC) will attempt to continue a three-game win streak when they visit the Louisville Cardinals (12-4, 2-2 ACC) on January 13, 2026 at KFC Yum! Center.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Louisville vs. Virginia Game Info and Odds

• Game day: Tuesday, January 13, 2026
• Game time: 7 p.m. ET
• TV channel: ESPN2
• Location: Louisville, Kentucky
• Arena: KFC Yum! Center

Before placing a wager on Tuesday's Louisville-Virginia spread (Louisville -4.5) or over/under (153.5 points), check out the betting trends and insights below.

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Louisville vs. Virginia: ATS Betting Stats and Trends

• Louisville has won nine games against the spread this season, while failing to cover seven times.
• Virginia has put together a 10-6-0 ATS record so far this season.
• Louisville covers the spread when it is a 4.5-point favorite or more 66.7% of the time. That's less often than Virginia covers as an underdog of 4.5 or more (100%).
• The Cardinals sport a better record against the spread when playing at home (6-4-0) than they do in road games (1-3-0).
• Against the spread last year, the Cavaliers had better results away (5-6-0) than at home (7-10-0).
• Louisville has one win against the spread in conference games this season.
• Virginia has beaten the spread three times in four ACC games.

Louisville vs. Virginia: Moneyline Betting Stats

• Louisville has been victorious in six of the eight contests it has been chosen as moneyline favorites in this season.
• This year, the Cardinals have won five of six games when listed as at least -210 or better on the moneyline.
• Virginia has been listed as the moneyline underdog just two other times so far this season, and it won both games.
• The Cavaliers have played as a moneyline underdog of +172 or longer in only one game this season, which they won.
• Louisville has an implied victory probability of 67.7% according to the moneyline set for this matchup.

Louisville vs. Virginia Head-to-Head Comparison

• At 78.5 points scored per game and 69.5 points conceded last year, Louisville was 65th in the country offensively and 89th on defense.
• Louisville grabbed 34.6 rebounds per game and gave up 30.2 boards last season, ranking 47th and 114th, respectively, in the nation.
• At 13.9 assists per game last year, Louisville was 148th in the nation.
• In terms of turnovers, Louisville was 150th in the country in committing them (10.9 per game) last year. It was 93rd in forcing them (12.2 per game).
• While Virginia ranked in the bottom 25 in the country in points per game last season with 64.8 (fifth-worst), it ranked 39th in college basketball with 66.8 points allowed per contest.
• Virginia struggled to collect rebounds last season, ranking worst in college basketball with 26.8 rebounds per game. It ranked 104th by allowing 30.1 boards per contest.
• Virginia delivered 14.7 dimes per game, which ranked them 93rd in college basketball.
• Virginia ranked 19th-worst in the country with 9.2 forced turnovers per game, but it helped combat that by ranking 25th-best in college basketball averaging 9.3 turnovers per contest.

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