Louisville vs Miami (FL) College Basketball Prediction, Odds, Picks, Best Bets for ACC Tournament

The No. 3 seed Miami Hurricanes (24-7, 13-5 ACC) will square off in the ACC tournament against the No. 6 seed Louisville Cardinals (23-9, 11-7 ACC) on Thursday at Spectrum Center, tipping off at 2:30 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Louisville vs. Miami (FL) Game Info and Odds

• Game day: Thursday, March 12, 2026
• Game time: 2:30 p.m. ET
• TV channel: ESPN2
• Location: Charlotte, North Carolina
• Arena: Spectrum Center

Louisville vs. Miami (FL) Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Louisville win (53.8%)

Before you bet on Thursday's Louisville-Miami (FL) spread (Louisville -1.5) or total (152.5 points), take a look at the betting insights and trends below.

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Louisville vs. Miami (FL): ATS Betting Stats and Trends

• Louisville has compiled a 16-16-0 ATS record so far this year.
• Miami (FL) has covered 17 times in 31 games with a spread this year.
• Louisville (15-13) covers a lower percentage of games when it is favored by 1.5 points or more this season (53.6%) than Miami (FL) (6-3) does as a 1.5+-point underdog (66.7%).
• When playing at home, the Cardinals sport a better record against the spread (10-7-0) compared to their ATS record in road games (3-8-0).
• The Hurricanes' winning percentage against the spread at home is .444 (8-10-0). On the road, it is .800 (8-2-0).
• Louisville has seven wins against the spread in 19 conference games this season.
• Against the spread in ACC play, Miami (FL) is 9-9-0 this year.

Louisville vs. Miami (FL): Moneyline Betting Stats

• Louisville has been the moneyline favorite in 22 games this season and has come away with the win 16 times (72.7%) in those contests.
• The Cardinals have a mark of 16-6 in contests where oddsmakers favor them by -120 or better on the moneyline.
• Miami (FL) has gone 5-4 in games it was the underdog on the moneyline (winning 55.6% of those games).
• When they have played as a moneyline underdog with odds of +100 or longer, the Hurricanes have a record of 4-4 (50%).
• Louisville has an implied victory probability of 54.5% according to the moneyline set for this matchup.

Louisville vs. Miami (FL) Head-to-Head Comparison

• Louisville outscores opponents by 13.1 points per game (scoring 85.1 per game to rank 18th in college basketball while allowing 72.0 per contest to rank 123rd in college basketball) and has a +420 scoring differential overall.
• Ryan Conwell's 18.6 points per game lead Louisville and are 68th in the country.
• Miami (FL) outscores opponents by 12.0 points per game (posting 82.7 points per game, 44th in college basketball, and conceding 70.7 per outing, 91st in college basketball) and has a +372 scoring differential.
• Malik Reneau is ranked 58th in college basketball with a team-leading 19.0 points per game.
• The 36.2 rebounds per game the Cardinals average rank 24th in the country, and are 5.9 more than the 30.3 their opponents grab per contest.
• Sananda Fru is 269th in college basketball play with 6.1 rebounds per game to lead the Cardinals.
• The Hurricanes win the rebound battle by an average of 8.0 boards. They are recording 34.5 rebounds per game (60th in college basketball) compared to their opponents' 26.5.
• Ernest Udeh Jr. is 23rd in the nation with 9.3 rebounds per game, leading the Hurricanes.
• Louisville ranks 25th in college basketball with 106.7 points scored per 100 possessions, and 61st in college basketball defensively with 90.3 points conceded per 100 possessions.
• The Hurricanes' 105.9 points per 100 possessions on offense rank 30th in college basketball, and the 90.5 points they concede per 100 possessions rank 66th in college basketball.

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