Iowa State vs Texas Tech College Basketball Prediction, Odds, Picks, Best Bets for Big 12 Tournament

The No. 5 seed Iowa State Cyclones (26-6, 12-6 Big 12) will square off against the No. 4 seed Texas Tech Red Raiders (22-9, 12-6 Big 12) in the Big 12 tournament Thursday at T-Mobile Center, beginning at 12:30 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Iowa State vs. Texas Tech Game Info and Odds

• Game day: Thursday, March 12, 2026
• Game time: 12:30 p.m. ET
• TV channel: ESPN
• Location: Kansas City, Missouri
• Arena: T-Mobile Center

Iowa State vs. Texas Tech Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Iowa State win (59.7%)

Take a look at the betting insights and trends below before placing a wager on Thursday's Iowa State-Texas Tech spread (Iowa State -5.5) or total (143.5 points).

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Iowa State vs. Texas Tech: ATS Betting Stats and Trends

• Iowa State is 18-14-0 ATS this season.
• Texas Tech has compiled a 16-15-0 record against the spread this year.
• As a 5.5-point underdog or more in 2025-26, Texas Tech is 4-0 against the spread compared to the 15-10 ATS record Iowa State racks up as a 5.5-point favorite.
• The Cyclones have done a better job covering the spread in home games (9-8-0) than they have in road games (5-5-0).
• This year, the Red Raiders are 9-7-0 at home against the spread (.562 winning percentage). On the road, they are 5-5-0 ATS (.500).
• Iowa State has 11 wins against the spread in 19 conference games this season.
• Against the spread in Big 12 games, Texas Tech is 11-7-0 this year.

Iowa State vs. Texas Tech: Moneyline Betting Stats

• Iowa State has been chosen as the moneyline favorite in 26 games this year and has walked away with the win 21 times (80.8%) in those games.
• This season, the Cyclones have been victorious 18 times in 21 chances when named as a favorite of at least -250 or shorter on the moneyline.
• Texas Tech has gone 4-4 in games it was the underdog on the moneyline (winning 50% of those games).
• The Red Raiders are 3-1 (winning 75% of their games) when they have played as a moneyline underdog of +202 or longer.
• The moneyline set for this matchup implies Iowa State has a 71.4% chance of coming away with a victory in the contest.

Iowa State vs. Texas Tech Head-to-Head Comparison

• Iowa State outscores opponents by 17.1 points per game (scoring 82.1 per game to rank 54th in college basketball while allowing 65.0 per outing to rank 11th in college basketball) and has a +546 scoring differential overall.
• Milan Momcilovic's team-leading 17.1 points per game ranks 153rd in college basketball.
• Texas Tech is outscoring opponents by 8.8 points per game, with a +271 scoring differential overall. It puts up 81.3 points per game (66th in college basketball) and gives up 72.5 per outing (139th in college basketball).
• Texas Tech's leading scorer, JT Toppin, is 11th in college basketball, averaging 21.8 points per game.
• The Cyclones grab 32.5 rebounds per game (143rd in college basketball) while conceding 28.3 per contest to their opponents. They outrebound opponents by 4.2 boards per game.
• Joshua Jefferson paces the team with 7.5 rebounds per game (106th in college basketball play).
• The Red Raiders win the rebound battle by an average of 3.4 boards. They are grabbing 34.0 rebounds per game (77th in college basketball) compared to their opponents' 30.6.
• Toppin is seventh in the nation with 10.8 rebounds per game, leading the Red Raiders.
• Iowa State ranks 27th in college basketball by averaging 106.6 points per 100 possessions on offense, and defensively is seventh in college basketball, allowing 84.5 points per 100 possessions.
• The Red Raiders record 104.4 points per 100 possessions (42nd in college basketball), while allowing 93.2 points per 100 possessions (127th in college basketball).

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