Iowa State vs Arizona State College Basketball Prediction, Odds, Picks, Best Bets for Big 12 Tournament

The No. 5 seed Iowa State Cyclones (25-6, 12-6 Big 12) and the No. 12 seed Arizona State Sun Devils (17-15, 7-11 Big 12) will look to advance in the Big 12 tournament on Wednesday as they meet at 12:30 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Iowa State vs. Arizona State Game Info and Odds

• Game day: Wednesday, March 11, 2026
• Game time: 12:30 p.m. ET
• TV channel: ESPN
• Location: Kansas City, Missouri
• Arena: T-Mobile Center

Iowa State vs. Arizona State Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Iowa State win (81.7%)

Before you wager on Wednesday's Iowa State-Arizona State spread (Iowa State -11.5) or total (148.5 points), read the betting trends and insights below.

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Iowa State vs. Arizona State: ATS Betting Stats and Trends

• Iowa State has covered 17 times in 31 matchups with a spread this season.
• Arizona State has won 20 games against the spread this year, while failing to cover 12 times.
• When the spread is set as 11.5 or more this season, Iowa State (9-7) covers a higher percentage of those games when it is the favorite (56.2%) than Arizona State (3-3) does as the underdog (50%).
• The Cyclones have done a better job covering the spread when playing at home (9-8-0) than they have in road affairs (5-5-0).
• In 2025-26 against the spread, the Sun Devils have a better winning percentage at home (.667, 10-5-0 record) than on the road (.455, 5-6-0).
• Iowa State's record against the spread in conference games is 10-8-0.
• Against the spread in Big 12 action, Arizona State is 12-7-0 this season.

Iowa State vs. Arizona State: Moneyline Betting Stats

• Iowa State has been the moneyline favorite in 25 games this season and has come away with the win 20 times (80%) in those contests.
• The Cyclones have been a -847 moneyline favorite on 11 occasions this season and won every game.
• Arizona State has gone 9-12 in games it was listed as the moneyline underdog (winning 42.9% of those games).
• The Sun Devils have played six times as a moneyline underdog with odds of +570 or longer, and fell in each game.
• The moneyline set for this matchup implies Iowa State has a 89.4% chance of coming away with a victory in the contest.

Iowa State vs. Arizona State Head-to-Head Comparison

• On offense, Iowa State was the 34th-ranked squad in college basketball (80.3 points per game) last season. Defensively, it was 61st (68.3 points allowed per game).
• Iowa State was 142nd in the country in rebounds per game (32.7) and 31st in rebounds conceded (28.3) last season.
• Last season Iowa State was ranked 77th in the nation in assists with 15.0 per game.
• In terms of turnovers, Iowa State was 232nd in the nation in committing them (11.6 per game) last season. It was 13th-best in forcing them (14.4 per game).
• With 74.1 points per game on offense, Arizona State was 165th in the country last season. Defensively, it ceded 76.8 points per contest, which ranked 310th in college basketball.
• Last season Arizona State grabbed 29.9 rebounds per game (300th-ranked in college basketball) and gave up 33.7 rebounds per contest (318th-ranked).
• Last year Arizona State ranked 241st in college basketball in assists, averaging 12.8 per game.
• Arizona State averaged 12.0 turnovers per game (259th-ranked in college basketball). It forced 10.8 turnovers per contest (225th-ranked).

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