Guardians vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for April 7

Odds updated as of 12:12 p.m.

The Cleveland Guardians versus the Kansas City Royals is on the MLB schedule for Tuesday.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs Royals Game Info

• Cleveland Guardians (6-5) vs. Kansas City Royals (5-5)
• Date: Tuesday, April 7, 2026
• Time: 1:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and Royals.TV

Guardians vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-118) | KC: (+100)
• Spread: CLE: +1.5 (-235) | KC: -1.5 (+190)
• Total: 6.5 -- Over: (-102) | Under: (-120)

Guardians vs Royals Probable Starting Pitchers

Probable Pitchers: Gavin Williams (Guardians) - 1-1, 2.25 ERA vs Noah Cameron (Royals) - 1-0, 1.80 ERA

The Guardians will give the nod to Gavin Williams (1-1, 2.25 ERA), who is eyeing win No. 2 on the season, and the Royals will turn to Noah Cameron (1-0, 1.80 ERA). Williams has a record of 1-1-0 ATS in two starts with a spread this season. Williams has yet to start a game this season when his team was the moneyline favorite. Cameron has started just one game with a set spread, which the Royals covered. The Royals were the underdog on the moneyline for one Cameron start this season -- they won.

Guardians vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (52%)

Guardians vs Royals Moneyline

• The Guardians vs Royals moneyline has Cleveland as a -118 favorite, while Kansas City is a +100 underdog on the road.

Guardians vs Royals Spread

• The Royals are 1.5-run favorites against the spread for this matchup with the Guardians. The Royals are +190 to cover, while the Guardians are -235 to cover as a 1.5-run underdog on the runline.

Guardians vs Royals Over/Under

• A total of 6.5 runs has been set for the Guardians-Royals game on April 7, with the over available at -102 and the under at -120.

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Guardians vs Royals Betting Trends

• The Guardians were defeated in the one game they played as the favorite this season.
• Cleveland has played as a favorite of -118 or more just one time this year and came away with a loss in that game.
• The Guardians and their opponents have gone over the total this season in four of their 11 opportunities.
• In 11 games with a line this season, the Guardians have a mark of 7-4-0 against the spread.
• The Royals have won three of the six games they were the moneyline underdog this season (50%).
• Kansas City has a record of 1-2 in games it has played as a moneyline underdog with odds of +100 or longer (33.3%).
• The Royals have had an over/under set by oddsmakers 10 times, and have combined with opponents to go over the total in three of those games (3-7-0).
• The Royals have collected a 5-5-0 record against the spread this season.

Guardians Player Leaders

• Chase DeLauter has 10 hits to go with a slugging percentage of .714, both of which are best among Cleveland hitters this season. He has a .286 batting average and an on-base percentage of .333.
• Among qualified hitters, he is 47th in batting average, his on-base percentage ranks 83rd, and he is sixth in slugging.
• Steven Kwan leads Cleveland in slugging percentage (.366) thanks to three extra-base hits. He's batting .244 with an on-base percentage of .326.
• Among qualifying batters, he ranks 87th in batting average, 89th in on-base percentage and 103rd in slugging percentage.
• Kwan has picked up at least one hit in two straight games. During his last five outings he is hitting .176 with a double, a home run, two walks and an RBI.
• Brayan Rocchio leads Cleveland in OBP (.351) this season, fueled by six hits.
• Jose Ramirez is batting .146 with a .239 OBP and five RBI for Cleveland this season.

Royals Player Leaders

• Maikel Garcia has put up a team-best OBP (.422) and slugging percentage (.526), while leading the Royals in hits (13, while batting .342).
• Including all the qualifying players in the majors, his batting average ranks 21st, his on-base percentage ranks 19th, and he is 42nd in slugging.
• Garcia heads into this game on a three-game hitting streak. In his last five games he is batting .364 with three doubles, a home run, two walks and four RBIs.
• Kyle Isbel is batting .444 with a double and two home runs. He's slugging .704 with an on-base percentage of .444.
• Jonathan India is batting .250 with two home runs and three walks.
• Salvador Perez is batting .184 with two doubles, two home runs and three walks.

Guardians vs Royals Head to Head

• 4/6/2026: 4-2 KC (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 9/11/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/10/2025: 4-3 KC (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/9/2025: 2-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/8/2025: 10-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/27/2025: 4-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/26/2025: 6-4 CLE (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/26/2025: 5-3 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/13/2025: 4-2 KC (Favorite: Royals, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/12/2025: 6-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)

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