Guardians vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for May 31

Odds updated as of 3:12 p.m.

The Cleveland Guardians are among the MLB teams busy on Saturday, versus the Los Angeles Angels.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Angels Game Info

• Cleveland Guardians (30-26) vs. Los Angeles Angels (26-30)
• Date: Saturday, May 31, 2025
• Time: 4:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and FDSW

Guardians vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-178) | LAA: (+150)
• Spread: CLE: -1.5 (+118) | LAA: +1.5 (-142)
• Total: 8 -- Over: (-108) | Under: (-112)

Guardians vs Angels Probable Starting Pitchers

Probable Pitchers: Slade Cecconi (Guardians) - 1-1, 3.27 ERA vs Kyle Hendricks (Angels) - 2-6, 5.23 ERA

This contest's pitching matchup is set, as the Guardians will send Slade Cecconi (1-1) to the mound, while Kyle Hendricks (2-6) will get the nod for the Angels. Cecconi has a record of 1-1-0 ATS in two starts with a spread this season. Cecconi's team lost his only start as a favorite this season. The Angels are 5-5-0 against the spread when Hendricks starts. The Angels have a 4-5 record in Hendricks' nine starts this season when they were the moneyline underdog.

Guardians vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (62%)

Guardians vs Angels Moneyline

• The moneyline numbers for Guardians vs. Angels reveal Cleveland as the favorite (-178) and Los Angeles as the underdog (+150) on the road.

Guardians vs Angels Spread

• The Angels are +1.5 on the run line against the Guardians. The Angels are -142 to cover, and the Guardians are +118.

Guardians vs Angels Over/Under

• A combined run total of 8 has been set for Guardians-Angels on May 31, with the over at -108 and the under at -112.

Bet on Cleveland Guardians vs. Los Angeles Angels on FanDuel today!

Guardians vs Angels Betting Trends

• The Guardians have been victorious in 11, or 57.9%, of the 19 contests they have been chosen as favorites in this season.
• Cleveland has been listed as a favorite of -178 or more on two occasions this season and won both games.
• The Guardians and their opponents have gone over the total this season in 26 of their 54 opportunities.
• The Guardians have posted a record of 25-29-0 against the spread this season.
• The Angels have put together a 21-24 record in games they were listed as the moneyline underdog (winning 46.7% of those games).
• Los Angeles has gone 5-7 when it has played as a moneyline underdog with odds of +150 or longer (41.7%).
• The Angels have played in 56 games with an over/under set, and have combined with opponents to go over the total 29 times (29-26-1).
• The Angels have covered 48.2% of their games this season, going 27-29-0 ATS.

Guardians Player Leaders

• Jose Ramirez has 65 hits and an OBP of .373, both of which are best among Cleveland hitters this season. He has a .319 batting average and a slugging percentage of .525.
• Among qualifying hitters in the majors, his batting average ranks 10th, his on-base percentage ranks 28th, and he is 15th in slugging.
• Steven Kwan has hit four homers this season while driving in 19 runs. He's batting .309 this season and slugging .419 with an on-base percentage of .367.
• He is 12th in batting average, 30th in on-base percentage and 87th in slugging among qualifying hitters.
• Carlos Santana has collected 46 base hits, an OBP of .366 and a slugging percentage of .383 this season.
• Santana has picked up a hit in nine games in a row. During his last 10 games he is batting .400 with two doubles, two home runs, eight walks and seven RBIs.
• Kyle Manzardo has 10 home runs, 28 RBI and a batting average of .215 this season.

Angels Player Leaders

• Taylor Ward has 11 doubles, a triple, 15 home runs and 17 walks while batting .220. He's slugging .491 with an on-base percentage of .272.
• Including all the qualified hitters in MLB, he is 147th in batting average, 159th in on-base percentage and 34th in slugging percentage.
• Nolan Schanuel leads his team with a .369 on-base percentage, and has a club-high .383 slugging percentage. He has a batting average of .277.
• Including all qualified hitters, he ranks 40th in batting average, 29th in on-base percentage and 115th in slugging percentage.
• Zach Neto has 10 doubles, nine home runs and seven walks while hitting .278.
• Logan O'Hoppe has 46 hits to pace his team.

Guardians vs Angels Head to Head

• 5/30/2025: 4-1 LAA (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/6/2025: 6-2 LAA (Favorite: Guardians, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/5/2025: 10-4 LAA (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/4/2025: 8-6 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/26/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/25/2024: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/24/2024: 10-4 CLE (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/5/2024: 4-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/4/2024: 7-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/3/2024: 6-0 LAA (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -198, Underdog Moneyline: +166)

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