Grizzlies vs. Clippers Prediction, Odds, Picks, Best Bets for Dec. 5

Grizzlies vs. Clippers Game Info

• Date: Friday, December 5, 2025
• Time: 8 p.m. ET
• Venue: FedExForum -- Memphis, Tennessee
• Coverage: FDSSE and FDSSC

The Memphis Grizzlies (9-13) are just 1.5-point underdogs against the Los Angeles Clippers (6-16) at FedExForum on Friday, December 5, 2025. The game starts at 8 p.m. ET on FDSSE and FDSSC. The over/under is 223.5 in the matchup.

Grizzlies vs. Clippers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Grizzlies vs. Clippers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Grizzlies win (60.8%)

Grizzlies vs. Clippers Betting Trends

• The Clippers have covered the spread in a game six times this season (6-16-0).
• The Grizzlies have nine wins against the spread in 22 games this season.
• This season, Clippers games have hit the over 13 times.
• The Grizzlies have gone over the point total 36.4% of the time this year (eight of 22 games with a set point total).
• Los Angeles owns a worse record against the spread in home games (1-9-0) than it does in away games (5-7-0).
• The Clippers have hit the over on the total in a higher percentage of games at home (60%) than away games (58.3%).
• In 2025-26 against the spread, Memphis has a lower winning percentage at home (.400, 4-6-0 record) than away (.417, 5-7-0).
• Looking at the over/under, Grizzlies games have gone over four of 10 times at home (40%), and four of 12 away (33.3%).

Clippers Leaders

• James Harden averages 26.9 points, 5.6 rebounds and 8.4 assists, shooting 43.7% from the floor and 36.8% from beyond the arc, with 3.7 made 3-pointers per contest (fourth in NBA).
• Ivica Zubac is averaging 16.2 points, 2.7 assists and 11.8 boards.
• Kawhi Leonard is averaging 25.9 points, 3 assists and 5.5 rebounds.
• John Collins is averaging 12 points, 5.1 rebounds and 0.6 assists.
• Kris Dunn is averaging 8 points, 2.6 rebounds and 2.6 assists.

Grizzlies Leaders

• Santi Aldama averages 13 points for the Grizzlies, plus 6.5 boards and 3 assists.
• Per game, Jaren Jackson Jr. gets the Grizzlies 17.8 points, 5.2 rebounds and 1.9 assists. He also averages 0.7 steals and 1 block.
• The Grizzlies get 13 points per game from Cedric Coward, plus 5.8 rebounds and 2.6 assists.
• Jock Landale's numbers on the season are 10.9 points, 5.5 rebounds and 1.5 assists per game. He is making 52.8% of his shots from the field and 44.4% from beyond the arc, with an average of 1.1 treys.
• Per game, Jaylen Wells gets the Grizzlies 11.8 points, 3.4 rebounds and 1.7 assists, plus 0.6 steals and 0 blocks.

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