Giants vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for April 30

Odds updated as of 4:15 p.m.

The Wednesday schedule in MLB includes a matchup between the San Francisco Giants and the San Diego Padres.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Giants vs Padres Game Info

• San Francisco Giants (19-11) vs. San Diego Padres (18-11)
• Date: Wednesday, April 30, 2025
• Time: 4:10 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and NBCS-BA

Giants vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-124) | SD: (+106)
• Spread: SF: -1.5 (+140) | SD: +1.5 (-172)
• Total: 6.5 -- Over: (-122) | Under: (-100)

Giants vs Padres Probable Starting Pitchers

Probable Pitchers: Landen Roupp (Giants) - 2-1, 4.56 ERA vs Michael King (Padres) - 3-1, 2.18 ERA

The Giants will give the nod to Landen Roupp (2-1, 4.56 ERA), who is eyeing win No. 3 on the season, and the Padres will turn to Michael King (3-1, 2.18 ERA). Roupp and his team have a record of 2-3-0 against the spread when he starts. Roupp's team has a record of 2-1 this season when he starts and they are the favorite on the moneyline. The Padres have a 3-3-0 ATS record in King's six starts with a set spread. The Padres were the underdog on the moneyline for one King start this season -- they won.

Giants vs Padres Moneyline

• The moneyline numbers for Giants vs. Padres reveal San Francisco as the favorite (-124) and San Diego as the underdog (+106) despite being the home team.

Giants vs Padres Spread

• The Giants are at the Padres and are favored by 1.5 runs (+140 to cover) on the runline. San Diego is -172 to cover.

Giants vs Padres Over/Under

• A combined run total of 6.5 has been set for Giants-Padres on April 30, with the over at -122 and the under at -100.

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Giants vs Padres Betting Trends

• The Giants have been chosen as favorites in 19 games this year and have walked away with the win 13 times (68.4%) in those games.
• This season San Francisco has been victorious 10 times in 16 chances when named as a favorite of at least -124 on the moneyline.
• Contests with the Giants have gone over the total set by oddsmakers in 17 of 30 chances this season.
• In 30 games with a line this season, the Giants have a mark of 14-16-0 against the spread.
• The Padres have won seven of the 14 games they were listed as the moneyline underdog this season (50%).
• San Diego has a record of 4-5 in games it has played as a moneyline underdog with odds of +106 or longer (44.4%).
• In the 29 games oddsmakers have set an over/under for the Padres, they have combined with opponents to go over the total 11 times (11-17-1).
• The Padres have gone 16-13-0 against the spread this season.

Giants Player Leaders

• Jung Hoo Lee leads San Francisco with 36 hits and an OBP of .379, plus a team-best slugging percentage of .536. He's batting .321.
• Among all qualified hitters in MLB, he is 11th in batting average, 29th in on-base percentage, and 22nd in slugging.
• Lee hopes to build on a six-game hitting streak in this matchup. During his last 10 games he is batting .250 with a double, a triple, three walks and three RBI.
• Wilmer Flores has seven home runs and seven walks. He's batting .238 and slugging .438 with an on-base percentage of .292.
• Among qualifying hitters, his batting average places him 97th, his on-base percentage 120th, and his slugging percentage 57th.
• Matt Chapman is batting .206 with a .392 slugging percentage and 16 RBI this year.
• Michael Yastrzemski leads San Francisco with an OBP of .379 this season while batting .264 with 15 walks and 12 runs scored.

Padres Player Leaders

• Fernando Tatis Jr. has a team-best OBP (.398) and slugging percentage (.596), while leading the Padres in hits (36, while batting .330).
• Including all the qualified hitters in the majors, his batting average ranks ninth, his on-base percentage is 16th, and he is seventh in slugging.
• Manny Machado is batting .280 with 10 doubles, two home runs and 10 walks. He's slugging .430 with an on-base percentage of .339.
• His batting average is 46th among all qualified players, his on-base percentage ranks 66th, and he is 62nd in slugging.
• Luis Arraez is batting .289 with three doubles, three home runs and five walks.
• Xander Bogaerts is hitting .253 with eight doubles, a home run and 13 walks.

Giants vs Padres Head to Head

• 4/29/2025: 7-4 SD (Favorite: Giants, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/15/2024: 4-3 SD (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/14/2024: 8-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/13/2024: 5-0 SD (Favorite: Padres, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/8/2024: 7-6 SF (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 9/7/2024: 6-3 SF (Favorite: Padres, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/6/2024: 5-1 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 4/7/2024: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 4/6/2024: 4-0 SD (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/5/2024: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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