Giants vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for June 18

Odds updated as of 9:12 a.m.

In MLB action on Wednesday, the San Francisco Giants play the Cleveland Guardians.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Giants vs Guardians Game Info

• San Francisco Giants (41-32) vs. Cleveland Guardians (36-35)
• Date: Wednesday, June 18, 2025
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and CLEG

Giants vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-134) | CLE: (+114)
• Spread: SF: -1.5 (+158) | CLE: +1.5 (-192)
• Total: 8 -- Over: (-100) | Under: (-122)

Giants vs Guardians Probable Starting Pitchers

Probable Pitchers: Justin Verlander (Giants) - 0-3, 4.50 ERA vs Logan Allen (Guardians) - 4-4, 4.28 ERA

This contest's pitching matchup is set, as the Giants will send Justin Verlander (0-3) to the mound, while Logan Allen (4-4) will take the ball for the Guardians. When Verlander starts, his team is 3-7-0 against the spread this season. Verlander's team has won 60% of his starts when they are favored on the moneyline (3-2). The Guardians are 4-7-0 against the spread when Allen starts. The Guardians have a 3-5 record in Allen's eight starts this season when they were the underdog on the moneyline.

Giants vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (56.8%)

Giants vs Guardians Moneyline

• San Francisco is the favorite, -134 on the moneyline, while Cleveland is a +114 underdog on the road.

Giants vs Guardians Spread

• The Guardians are at +1.5 on the runline against the Giants. The Guardians are -192 to cover the spread, and the Giants are +158.

Giants vs Guardians Over/Under

• A total of 8 runs has been set for the Giants-Guardians game on June 18, with the over available at -100 and the under at -122.

Bet on San Francisco Giants vs. Cleveland Guardians on FanDuel today!

Giants vs Guardians Betting Trends

• The Giants have been favorites in 46 games this season and have come away with the win 27 times (58.7%) in those contests.
• San Francisco has a record of 21-12 when favored by -134 or more this year.
• The Giants and their opponents have hit the over in 33 of their 73 games with a total set by oddsmakers this season.
• The Giants have an against the spread record of 34-39-0 in 73 games with a line this season.
• The Guardians have won 44.4% of the games this season they were the underdog on the moneyline (20-25).
• Cleveland has an 8-12 record (winning 40% of its games) when it has played as a moneyline underdog of +114 or longer.
• In the 69 games bookmakers have set an over/under for the Guardians, they have combined with opponents to go over the total 31 times (31-35-3).
• The Guardians have collected a 34-35-0 record ATS this season (covering 49.3% of the time).

Giants Player Leaders

• Rafael Devers leads San Francisco with 76 hits and an OBP of .401 this season. He has a .274 batting average and a slugging percentage of .505.
• Among qualified hitters in the majors, he is 48th in batting average, sixth in on-base percentage, and 19th in slugging.
• Devers will look for his third straight game with a hit in this contest. In his last five games he is hitting .211 with a double, a home run, two walks and two RBIs.
• Jung Hoo Lee has 17 doubles, five triples, six home runs and 25 walks. He's batting .265 and slugging .430 with an on-base percentage of .328.
• Among all qualifying hitters, he ranks 62nd in batting average, 78th in on-base percentage and 74th in slugging percentage.
• Lee heads into this game looking to extend his two-game hit streak. During his last five outings he is batting .143 with a triple, four walks and two RBIs.
• Heliot Ramos has hit 11 homers with a team-high .461 SLG this season.
• Wilmer Flores has been key for San Francisco with 65 hits, an OBP of .323 plus a slugging percentage of .408.

Guardians Player Leaders

• Jose Ramirez has totaled 83 hits with a .380 on-base percentage and a .535 slugging percentage, all club-highs for the Guardians. He's batting .319.
• Including all qualified hitters in MLB, his batting average puts him seventh, his on-base percentage ranks 16th, and he is 10th in slugging.
• Steven Kwan has 14 doubles, six home runs and 25 walks while batting .298. He's slugging .420 with an on-base percentage of .363.
• Including all qualifying players, he is 16th in batting average, 30th in on-base percentage and 86th in slugging percentage.
• Carlos Santana is hitting .248 with six doubles, eight home runs and 32 walks.
• Kyle Manzardo is hitting .207 with eight doubles, two triples, 11 home runs and 23 walks.

Giants vs Guardians Head to Head

• 6/17/2025: 3-2 CLE (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/7/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/6/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/5/2024: 4-2 SF (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/13/2023: 6-5 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/12/2023: 3-1 CLE (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 9/11/2023: 5-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!