Giants vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for June 18

Odds updated as of 9:11 p.m.

In MLB action on Wednesday, the San Francisco Giants take on the Cleveland Guardians.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this game.

Giants vs Guardians Game Info

• San Francisco Giants (41-32) vs. Cleveland Guardians (36-35)
• Date: Wednesday, June 18, 2025
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and CLEG

Giants vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-162) | CLE: (+136)
• Spread: SF: -1.5 (+136) | CLE: +1.5 (-164)
• Total: 7 -- Over: (-105) | Under: (-115)

Giants vs Guardians Probable Starting Pitchers

Probable Pitchers: Justin Verlander (Giants) - 0-3, 4.50 ERA vs Logan Allen (Guardians) - 4-4, 4.28 ERA

The Giants will look to Justin Verlander (0-3) against the Guardians and Logan Allen (4-4). When Verlander starts, his team is 3-7-0 against the spread this season. Verlander's team is 3-2 this season when he starts and they are the moneyline favorite. The Guardians are 4-7-0 ATS in Allen's 11 starts with a set spread. The Guardians have been the moneyline underdog in eight of Allen's starts this season, and they went 3-5 in those games.

Giants vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (56.8%)

Giants vs Guardians Moneyline

• Cleveland is a +136 underdog on the moneyline, while San Francisco is a -162 favorite at home.

Giants vs Guardians Spread

• The Guardians are at the Giants, and are +1.5 on the runline. The Guardians are +136 to cover the spread, and the Giants are -164.

Giants vs Guardians Over/Under

• An over/under of 7 has been set for Giants-Guardians on June 18, with the over being -105 and the under -115.

Bet on San Francisco Giants vs. Cleveland Guardians on FanDuel today!

Giants vs Guardians Betting Trends

• The Giants have won in 27, or 58.7%, of the 46 contests they have been named as odds-on favorites in this year.
• San Francisco has a record of 9-5 when favored by -162 or more this year.
• The Giants and their opponents have gone over the total this season in 33 of their 73 opportunities.
• The Giants are 34-39-0 against the spread in their 73 games that had a posted line this season.
• The Guardians have won 44.4% of the games this season they were the underdog on the moneyline (20-25).
• When it has played as a moneyline underdog with odds of +136 or longer, Cleveland has a record of 4-9 (30.8%).
• The Guardians have played in 69 games with a set over/under, and have combined with opponents to go over the total 31 times (31-35-3).
• The Guardians have put together a 34-35-0 record against the spread this season (covering 49.3% of the time).

Giants Player Leaders

• Rafael Devers has 76 hits and an OBP of .401, both of which are tops among San Francisco hitters this season. He has a .274 batting average and a slugging percentage of .505.
• Among qualified hitters in the majors, he ranks 48th in batting average, sixth in on-base percentage, and 19th in slugging.
• Devers hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .211 with a double, a home run, two walks and two RBIs.
• Jung Hoo Lee is batting .265 with 17 doubles, five triples, six home runs and 25 walks. He's slugging .430 with an on-base percentage of .328.
• His batting average is 62nd among qualified players, his on-base percentage 78th, and his slugging percentage 73rd.
• Lee has picked up at least one hit in two straight games. In his last five games he is batting .143 with a triple, four walks and two RBIs.
• Heliot Ramos has hit 11 homers with a team-high .461 SLG this season.
• Wilmer Flores has 11 home runs, 51 RBI and a batting average of .255 this season.

Guardians Player Leaders

• Jose Ramirez has accumulated 83 hits with a .380 on-base percentage and a .535 slugging percentage, all club-highs for the Guardians. He's batting .319.
• He is seventh in batting average, 16th in on-base percentage and 10th in slugging percentage among all qualifying batters in MLB.
• Steven Kwan has 14 doubles, six home runs and 25 walks while hitting .298. He's slugging .420 with an on-base percentage of .363.
• He is currently 16th in batting average, 30th in on-base percentage and 85th in slugging percentage among all qualified hitters.
• Carlos Santana is batting .248 with six doubles, eight home runs and 32 walks.
• Kyle Manzardo is batting .207 with eight doubles, two triples, 11 home runs and 23 walks.

Giants vs Guardians Head to Head

• 6/17/2025: 3-2 CLE (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/7/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/6/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/5/2024: 4-2 SF (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/13/2023: 6-5 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/12/2023: 3-1 CLE (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 9/11/2023: 5-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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