Duke vs Wake Forest College Basketball Prediction, Odds, Picks, Best Bets for Jan. 24

The Duke Blue Devils (17-1, 6-0 ACC) will try to build on a six-game winning streak when they host the Wake Forest Demon Deacons (11-8, 2-4 ACC) on January 24, 2026 at Cameron Indoor Stadium.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Duke vs. Wake Forest Game Info and Odds

• Game day: Saturday, January 24, 2026
• Game time: 12 p.m. ET
• TV channel: The CW Network
• Location: Durham, North Carolina
• Arena: Cameron Indoor Stadium

Duke vs. Wake Forest Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Duke win (91.3%)

See the betting insights and trends below before placing a bet on Saturday's Duke-Wake Forest spread (Duke -17.5) or total (150.5 points).

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Duke vs. Wake Forest: ATS Betting Stats and Trends

• Duke has covered nine times in 18 games with a spread this season.
• Wake Forest has won seven games against the spread this season, while failing to cover 12 times.
• The Blue Devils have a worse record against the spread in home games (2-6-0) than they do in road games (5-1-0).
• In 2024-25 against the spread, the Demon Deacons had a lower winning percentage at home (.375, 6-10-0 record) than away (.500, 6-6-0).
• Duke's record against the spread in conference action is 3-3-0.
• Wake Forest has won once against the spread in ACC play this season.

Duke vs. Wake Forest: Moneyline Betting Stats

• Duke has been the moneyline favorite in 12 games this season and has come away with the win 11 times (91.7%) in those contests.
• The Blue Devils have played as a favorite of -3448 or more just one time this year and came away with a win in that game.
• Wake Forest has won one of the seven games it was the moneyline underdog this season (14.3%).
• The Demon Deacons have yet to play as a moneyline underdog of +1280 or longer.
• Duke has an implied victory probability of 97.2% according to the moneyline set for this matchup.

Duke vs. Wake Forest Head-to-Head Comparison

• Duke is outscoring opponents by 20.4 points per game with a +368 scoring differential overall. It puts up 85.5 points per game (32nd in college basketball) and allows 65.1 per outing (18th in college basketball).
• Cameron Boozer leads Duke, averaging 23.2 points per game (fourth in the nation).
• Wake Forest outscores opponents by 5.1 points per game (posting 80.9 points per game, 93rd in college basketball, and giving up 75.8 per outing, 234th in college basketball) and has a +97 scoring differential.
• Juke Harris leads Wake Forest, recording 20.5 points per game (21st in college basketball).
• The Blue Devils record 37.2 rebounds per game (26th in college basketball) while conceding 28.3 per outing to their opponents. They outrebound opponents by 8.9 boards per game.
• Boozer averages 9.9 rebounds per game (ranking 17th in college basketball) to lead the Blue Devils.
• The Demon Deacons rank 275th in the nation at 30.6 rebounds per game. That's 1.3 fewer than the 31.9 their opponents average.
• Harris is 237th in the nation with 6.4 rebounds per game, leading the Demon Deacons.
• Duke ranks 22nd in college basketball with 107.7 points scored per 100 possessions, and eighth in college basketball defensively with 82 points conceded per 100 possessions.
• The Demon Deacons' 98.6 points per 100 possessions on offense rank 167th in college basketball, and the 92.3 points they allow per 100 possessions rank 149th in college basketball.

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