Duke vs UConn College Basketball Prediction, Odds, Picks, Best Bets for NCAA Tournament Elite Eight

The No. 1 seed Duke Blue Devils (35-2) will match up with the No. 2 seed UConn Huskies (32-5) in the NCAA Tournament Elite Eight on Sunday at Capital One Arena, airing on CBS starting at 5:05 p.m. ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Duke vs. UConn Game Info and Odds

• Game day: Sunday, March 29, 2026
• Game time: 5:05 p.m. ET
• TV channel: CBS
• Location: Washington D.C.
• Arena: Capital One Arena

Duke vs. UConn Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Duke win (62%)

Read these betting insights and trends before you bet on Sunday's Duke-UConn spread (Duke -5.5) or total (134.5 points).

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Duke vs. UConn: ATS Betting Stats and Trends

• Duke has covered 19 times in 37 chances against the spread this season.
• UConn is 14-23-0 ATS this year.
• Against the spread, the Blue Devils have fared worse when playing at home, covering six times in 15 home games, and eight times in 11 road games.
• The Huskies have been better against the spread away (5-6-0) than at home (4-13-0) this season.

Duke vs. UConn: Moneyline Betting Stats

• Duke has won in 28, or 93.3%, of the 30 contests it has been named as the moneyline favorite in this year.
• The Blue Devils have a win-loss record of 26-2 when favored by -230 or better by bookmakers this year.
• UConn is the moneyline underdog in its first game this season.
• The Huskies have yet to play a game with moneyline odds of +188 or longer.
• The moneyline set for this matchup implies Duke has a 69.7% chance of coming away with a victory in the contest.

Duke vs. UConn Head-to-Head Comparison

• Offensively, Duke was the 11th-best team in the nation (83.2 points per game) last year. On defense, it was seventh-best (62.8 points conceded per game).
• Duke was the 24th-best team in college basketball in rebounds per game (35.6) and 12th-best in rebounds conceded (27.3) last season.
• Last season Duke was 17th-best in college basketball in assists with 16.9 per game.
• Last year, Duke was ninth-best in college basketball in turnovers committed (8.9 per game) and ranked 265th in turnovers forced (10.4).
• On offense, UConn put up 77 points per game (90th-ranked in college basketball) last year. It gave up 68 points per contest at the other end of the court (56th-ranked).
• UConn pulled down 33.1 rebounds per game last year (111th-ranked in college basketball), and it gave up just 25.9 rebounds per game (second-best).
• UConn piled up assists last season, ranking eighth-best in the country with 17.3 per contest.
• UConn committed 10 turnovers per game (71st-ranked in college basketball) this season, while forcing 9.8 turnovers per contest (317th-ranked).

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