Duke vs North Carolina College Basketball Prediction, Odds, Picks, Best Bets for March 7

A pair of streaking teams square off when the Duke Blue Devils (28-2, 16-1 ACC) host the North Carolina Tar Heels (24-6, 12-5 ACC) on March 7, 2026. The Blue Devils will put their seven-game win streak on the line against the Tar Heels, who have won four straight.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Duke vs. North Carolina Game Info and Odds

• Game day: Saturday, March 7, 2026
• Game time: 6:30 p.m. ET
• TV channel: ESPN
• Location: Durham, North Carolina
• Arena: Cameron Indoor Stadium

Duke vs. North Carolina Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Duke win (83.8%)

Before you bet on Saturday's Duke-North Carolina spread (Duke -16.5) or total (144.5 points), see the betting trends and insights below.

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Duke vs. North Carolina: ATS Betting Stats and Trends

• Duke has covered 17 times in 30 matchups with a spread this season.
• North Carolina has put together a 17-13-0 record against the spread this season.
• Against the spread, the Blue Devils have fared worse at home, covering six times in 14 home games, and eight times in 11 road games.
• The Tar Heels' winning percentage against the spread at home is .667 (12-6-0). Away, it is .444 (4-5-0).
• Against the spread, in conference action, Duke is 10-7-0 this year.
• Against the spread in ACC games, North Carolina is 9-8-0 this season.

Duke vs. North Carolina: Moneyline Betting Stats

• Duke has won in 21, or 91.3%, of the 23 contests it has been named as the moneyline favorite in this year.
• The Blue Devils have been a -2326 moneyline favorite on seven occasions this season and won every game.
• North Carolina is 5-3 in games it was the underdog on the moneyline (winning 62.5% of those games).
• The Tar Heels have not played a game this season with moneyline odds of +1060 or longer.
• Sportsbooks have implied with the moneyline set for this matchup that Duke has a 95.9% chance of pulling out a win.

Duke vs. North Carolina Head-to-Head Comparison

• Duke averages 83.2 points per game (39th in college basketball) while allowing 62.5 per contest (third in college basketball). It has a +619 scoring differential overall and outscores opponents by 20.7 points per game.
• Duke's leading scorer, Cameron Boozer, ranks seventh in the nation scoring 22.6 points per game.
• North Carolina has a +287 scoring differential, topping opponents by 9.5 points per game. It is putting up 80.4 points per game, 78th in college basketball, and is allowing 70.9 per contest to rank 100th in college basketball.
• Caleb Wilson's 19.9 points per game leads North Carolina and ranks 35th in the nation.
• The Blue Devils grab 37.2 rebounds per game (11th in college basketball) while conceding 26.6 per outing to their opponents. They outrebound opponents by 10.6 boards per game.
• Boozer tops the Blue Devils with 10 rebounds per game (14th in college basketball play).
• The Tar Heels win the rebound battle by 4.9 boards on average. They collect 34.9 rebounds per game, 49th in college basketball, while their opponents pull down 30.
• Wilson is 21st in the country with 9.4 rebounds per game, leading the Tar Heels.
• Duke ranks 10th in college basketball with 109.2 points scored per 100 possessions, and second in college basketball defensively with 82.1 points conceded per 100 possessions.
• The Tar Heels rank 62nd in college basketball averaging 103.1 points per 100 possessions on offense, and defensively are 71st, allowing 90.8 points per 100 possessions.

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