Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 27

Odds updated as of 4:11 a.m.

On Sunday in MLB, the Los Angeles Dodgers are playing the San Francisco Giants.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (99-62) vs. San Francisco Giants (65-96)
• Date: Sunday, September 27, 2026
• Time: 3:05 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and SportsNet LA

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-260) | SF: (+215)
• Spread: LAD: -1.5 (-144) | SF: +1.5 (+120)
• Total: 8.5 -- Over: (+110) | Under: (-134)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: TBA (Dodgers) vs Carson Seymour (Giants) - 0-2, 0.00 ERA

Seymour (0-2) will get the nod for the Giants. As of this writing, there's been no pitching decision announced by the Dodgers. Last season Seymour and his team went 1-2-0 against the spread when he pitched. Seymour and his team went 1-1 in games he appeared in when they were moneyline underdogs a season ago.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (57.4%)

Dodgers vs Giants Moneyline

• Looking at the moneyline for Dodgers-Giants, Los Angeles is the favorite at -260, and San Francisco is +215 playing at home.

Dodgers vs Giants Spread

• The Giants are hosting the Dodgers, and are +1.5 on the runline. The Giants are -144 to cover the spread, and the Dodgers are +120.

Dodgers vs Giants Over/Under

• An over/under of 8.5 has been set for Dodgers-Giants on Sept. 27, with the over being +110 and the under -134.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have been victorious in 96, or 62.7%, of the 153 contests they have been chosen as favorites in this season.
• Los Angeles has a record of 23-7 when favored by -260 or more this year.
• The Dodgers and their opponents have hit the over in 73 of their 159 games with a total set by oddsmakers this season.
• The Dodgers have posted a record of 67-92-0 against the spread this season.
• The Giants have won 35.7% of the games this season they were the moneyline underdog (40-72).
• San Francisco has a record of 1-5 when playing as a moneyline underdog with odds of +215 or longer (16.7%).
• The Giants have played in 158 games with an over/under set, and have combined with their opponents to go over the total 76 times (76-72-10).
• The Giants have covered 48.1% of their games this season, going 76-82-0 ATS.

Dodgers Player Leaders

• Shohei Ohtani leads Los Angeles in OBP (.377) and total hits (143) this season. He's batting .275 batting average while slugging .513.
• Among qualifying batters in baseball, his batting average ranks 35th, his on-base percentage ranks 11th, and he is 11th in slugging.
• Freddie Freeman has an OPS of .796, fueled by an OBP of .364 and a team-best slugging percentage of .432 this season. He's batting .290.
• He is 11th in batting average, 24th in on-base percentage and 62nd in slugging in the major leagues.
• Kyle Tucker has collected 125 base hits, an OBP of .331 and a slugging percentage of .387 this season.
• Mookie Betts is batting .258 with a .327 OBP and 69 RBI for Los Angeles this season.

Giants Player Leaders

• Drew Gilbert is batting .240 with 14 doubles, three triples, 11 home runs and 38 walks. He's slugging .396 with an on-base percentage of .330.
• Marcelo Mayer is batting .208 with 10 doubles, three home runs and 18 walks. He's slugging .296 with an on-base percentage of .275.
• Christian Koss is hitting .221 with six doubles, four home runs and nine walks.
• Jonah Cox has four doubles, two triples, four home runs and 10 walks while hitting .259.

Dodgers vs Giants Head to Head

• 9/26/2026: 4-3 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -300, Underdog Moneyline: +245)
• 9/25/2026: 2-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -330, Underdog Moneyline: +265)
• 9/20/2026: 3-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 9/19/2026: 10-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -450, Underdog Moneyline: +350)
• 9/18/2026: 8-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -320, Underdog Moneyline: +260)
• 5/14/2026: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/13/2026: 4-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 5/12/2026: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 5/11/2026: 9-3 SF (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/23/2026: 3-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)

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