Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 27

Odds updated as of 2:11 p.m.

The Los Angeles Dodgers are among the MLB squads busy on Sunday, up against the San Francisco Giants.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (99-62) vs. San Francisco Giants (65-96)
• Date: Sunday, September 27, 2026
• Time: 3:05 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and SportsNet LA

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-255) | SF: (+210)
• Spread: LAD: -1.5 (-140) | SF: +1.5 (+116)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Jack Dreyer (Dodgers) - 5-2, 3.16 ERA vs Carson Seymour (Giants) - 0-2, 4.70 ERA

The Dodgers will look to Jack Dreyer (5-2) versus the Giants and Carson Seymour (0-2). Dreyer has a record of 1-1-0 ATS in two starts with a spread this season. Dreyer's team is 1-1 this season when he starts and they're favored on the moneyline. Last season when Seymour pitched his team finished 1-2-0 against the spread. Seymour and his team went 1-1 in games he appeared in when they were the underdog on the moneyline a season ago.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (58.2%)

Dodgers vs Giants Moneyline

• Looking at the moneyline for Giants-Dodgers, San Francisco is the underdog at +210, and Los Angeles is -255 playing on the road.

Dodgers vs Giants Spread

• The Dodgers are at the Giants and are favored by 1.5 runs (-140 to cover) on the runline. San Francisco is +116 to cover.

Dodgers vs Giants Over/Under

• Dodgers versus Giants on Sept. 27 has an over/under of 8.5 runs, with the odds on the over -105 and the under set at -115.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have been chosen as favorites in 153 games this year and have walked away with the win 96 times (62.7%) in those games.
• This season Los Angeles has come away with a win 25 times in 33 chances when named as a favorite of at least -255 on the moneyline.
• The Dodgers and their opponents have gone over in 73 of their 159 games with a total set by sportsbooks this season.
• The Dodgers have an against the spread record of 67-92-0 in 159 games with a line this season.
• The Giants have won 40 of the 112 games they were the underdog on the moneyline this season (35.7%).
• When playing as a moneyline underdog with odds of +210 or longer, San Francisco has gone 1-6 (14.3%).
• The Giants have played in 158 games with an over/under set, and have combined with their opponents to go over the total 76 times (76-72-10).
• The Giants have a 76-82-0 record ATS this season (covering 48.1% of the time).

Dodgers Player Leaders

• Shohei Ohtani leads Los Angeles in OBP (.377) and total hits (143) this season. He's batting .275 batting average while slugging .513.
• Among the qualifying hitters in MLB, his batting average ranks 35th, his on-base percentage ranks 11th, and he is 11th in slugging.
• Kyle Tucker has 23 doubles, four triples, 17 home runs and 78 walks. He's batting .234 and slugging .387 with an on-base percentage of .331.
• He ranks 106th in batting average, 67th in on-base percentage and 105th in slugging among qualified batters.
• Freddie Freeman has an OPS of .796, fueled by an OBP of .364 and a team-best slugging percentage of .432 this season.
• Mookie Betts has 23 home runs, 69 RBI and a batting average of .258 this season.

Giants Player Leaders

• Drew Gilbert is hitting .240 with 14 doubles, three triples, 11 home runs and 38 walks. He's slugging .396 with an on-base percentage of .330.
• Marcelo Mayer has 10 doubles, three home runs and 18 walks while hitting .208. He's slugging .296 with an on-base percentage of .275.
• Christian Koss is batting .221 with six doubles, four home runs and nine walks.
• Jonah Cox has four doubles, two triples, four home runs and 10 walks while batting .259.

Dodgers vs Giants Head to Head

• 9/26/2026: 4-3 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -300, Underdog Moneyline: +245)
• 9/25/2026: 2-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -330, Underdog Moneyline: +265)
• 9/20/2026: 3-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 9/19/2026: 10-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -450, Underdog Moneyline: +350)
• 9/18/2026: 8-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -320, Underdog Moneyline: +260)
• 5/14/2026: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/13/2026: 4-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 5/12/2026: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 5/11/2026: 9-3 SF (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/23/2026: 3-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)

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