Guardians vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 27

Odds updated as of 12:11 a.m.

MLB action on Sunday includes the Cleveland Guardians facing the Kansas City Royals.

We've got you covered, in terms of the vital information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Royals Game Info

• Cleveland Guardians (85-76) vs. Kansas City Royals (68-93)
• Date: Sunday, September 27, 2026
• Time: 3:10 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: Royals.TV and CleGuardians.TV

Guardians vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-146) | KC: (+124)
• Spread: CLE: -1.5 (+114) | KC: +1.5 (-137)
• Total: 8.5 -- Over: (-108) | Under: (-112)

Guardians vs Royals Probable Starting Pitchers

Probable Pitchers: TBA (Guardians) vs Daniel Lynch (Royals) - 6-6, 0.00 ERA

The Royals will look to Lynch (6-6, 3.06), while the Guardians' starter for this game has yet to be announced. The Royals have a 3-5-0 ATS record in Lynch's eight starts that had a set spread. The Royals have been the moneyline underdog in six of Lynch's starts this season, and they went 3-3 in those games.

Guardians vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (59.6%)

Guardians vs Royals Moneyline

• Kansas City is a +124 underdog on the moneyline, while Cleveland is a -146 favorite on the road.

Guardians vs Royals Spread

• The Royals are +1.5 on the spread (-137 to cover), and Cleveland is +114 to cover the runline.

Guardians vs Royals Over/Under

• A total of 8.5 runs has been set for the Guardians-Royals contest on Sept. 27, with the over available at -108 and the under at -112.

Bet on Cleveland Guardians vs. Kansas City Royals on FanDuel today!

Guardians vs Royals Betting Trends

• The Guardians have won in 48, or 53.3%, of the 90 contests they have been named as odds-on favorites in this year.
• This season Cleveland has been victorious 21 times in 30 chances when named as a favorite of at least -146 on the moneyline.
• The Guardians' games have gone over the total in 74 of their 151 opportunities.
• In 151 games with a line this season, the Guardians have a mark of 73-78-0 against the spread.
• The Royals have won 39 of the 102 games they were the moneyline underdog this season (38.2%).
• When it has played as a moneyline underdog with odds of +124 or longer, Kansas City has gone 14-25 (35.9%).
• The Royals have played in 153 games with a set over/under, and have combined with opponents to go over the total 71 times (71-79-3).
• The Royals have covered 49.7% of their games this season, going 76-77-0 against the spread.

Guardians Player Leaders

• Chase DeLauter leads Cleveland with 142 hits, batting .287 this season with 49 extra-base hits. He has an on-base percentage of .363 and a slugging percentage of .457.
• He is 14th in batting average, 25th in on-base percentage, and 42nd in slugging among qualifying hitters in baseball.
• DeLauter hopes to build on a two-game hitting streak in this matchup. In his last five games he is hitting .200 with two doubles, a home run, three walks and two RBIs.
• Steven Kwan leads the Guardians with an OPS of .731. He has a slash line of .282/.382/.349 this season.
• His batting average ranks 20th among qualified players, his on-base percentage eighth, and his slugging percentage 130th.
• Jose Ramirez has collected 111 base hits, an OBP of .320 and a slugging percentage of .368 this season.
• Brayan Rocchio has been key for Cleveland with 135 hits, an OBP of .313 plus a slugging percentage of .391.
• Rocchio brings a two-game hitting streak into this game. In his last five games he is batting .316 with a double, two home runs, a walk and three RBIs.

Royals Player Leaders

• Bobby Witt Jr. has accumulated a .361 on-base percentage and a .444 slugging percentage, both team-high numbers for the Royals. He's batting .283.
• Including all qualifying hitters in MLB, he is 17th in batting average, 29th in on-base percentage and 51st in slugging percentage.
• Witt takes an eight-game hitting streak into this game. During his last 10 games he is batting .333 with three doubles and four walks.
• Carter Jensen has 35 doubles, two triples, 27 home runs and 65 walks while hitting .239. He's slugging .467 with an on-base percentage of .323.
• He is currently 98th in batting average, 81st in on-base percentage and 36th in slugging percentage among all qualified hitters.
• Jac Caglianone has put up 146 hits, a team-best for the Royals.
• Vinnie Pasquantino is batting .247 with 20 doubles, two triples, 15 home runs and 51 walks.

Guardians vs Royals Head to Head

• 9/26/2026: 11-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/30/2026: 11-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +164)
• 8/29/2026: 8-3 KC (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +146)
• 8/28/2026: 3-0 KC (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +120)
• 5/7/2026: 8-5 CLE (Favorite: Royals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/6/2026: 3-1 CLE (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 5/5/2026: 5-3 KC (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/4/2026: 6-2 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/8/2026: 10-2 CLE (Favorite: Royals, Spread: -1.5, Total: 7, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/7/2026: 2-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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