Cubs vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for May 31

Odds updated as of 2:12 p.m.

The Chicago Cubs will face the Cincinnati Reds in MLB action on Saturday.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Reds Game Info

• Chicago Cubs (35-22) vs. Cincinnati Reds (29-29)
• Date: Saturday, May 31, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MLB Network, MARQ, and FDSOH

Cubs vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-178) | CIN: (+150)
• Spread: CHC: -1.5 (+130) | CIN: +1.5 (-156)
• Total: 7 -- Over: (-114) | Under: (-106)

Cubs vs Reds Probable Starting Pitchers

Probable Pitchers: Drew Pomeranz (Cubs) - 2-0, 0.00 ERA vs Nick Lodolo (Reds) - 4-4, 3.39 ERA

The Cubs will look to Drew Pomeranz (2-0) versus the Reds and Nick Lodolo (4-4). Pomeranz did not appear in a game when his team was the moneyline favorite last season. When Lodolo starts, the Reds have gone 6-5-0 against the spread. The Reds are 2-3 in Lodolo's five starts this season that they were the moneyline underdog.

Cubs vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (55.1%)

Cubs vs Reds Moneyline

• Looking at the moneyline for Cubs-Reds, Chicago is the favorite at -178, and Cincinnati is +150 playing on the road.

Cubs vs Reds Spread

• The Reds are +1.5 on the run line against the Cubs. The Reds are -156 to cover, and the Cubs are +130.

Cubs vs Reds Over/Under

• Cubs versus Reds, on May 31, has an over/under of 7, with the over being -114 and the under -106.

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Cubs vs Reds Betting Trends

• The Cubs have won in 25, or 71.4%, of the 35 contests they have been named as odds-on favorites in this year.
• This year Chicago has won eight of nine games when listed as at least -178 on the moneyline.
• The Cubs and their opponents have gone over the total this season in 33 of their 55 opportunities.
• The Cubs have an against the spread record of 28-27-0 in 55 games with a line this season.
• The Reds have won 16 of the 32 games they were the underdog on the moneyline this season (50%).
• Cincinnati is 1-3 (winning only 25% of its games) when it has played as a moneyline underdog of +150 or longer.
• The Reds have combined with opponents to go over the total 23 times this season for a 23-31-2 record against the over/under.
• The Reds have a 30-26-0 record against the spread this season.

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.385) this season, fueled by 61 hits. He has a .277 batting average and a slugging percentage of .518.
• Among qualifying hitters in MLB, he is 40th in batting average, 18th in on-base percentage, and 19th in slugging.
• Pete Crow-Armstrong leads Chicago in slugging percentage (.562) thanks to 32 extra-base hits. He's batting .274 with an on-base percentage of .303.
• He is 45th in batting average, 128th in on-base percentage and ninth in slugging among qualified hitters.
• Crow-Armstrong enters this game looking to extend his two-game hit streak. During his last five outings he is batting .190 with a double, a home run and four RBIs.
• Seiya Suzuki has 58 hits and is batting .272 this season.
• Suzuki takes a 10-game hitting streak into this game. In his last 10 games he is hitting .400 with seven doubles, three home runs, six walks and 12 RBIs.
• Nico Hoerner has no home runs, but 24 RBI and a batting average of .288 this season.

Reds Player Leaders

• Elly De La Cruz paces the Reds with 58 hits. He's batting .256 and slugging .445 with an on-base percentage of .328.
• He is 86th in batting average, 78th in on-base percentage and 63rd in slugging percentage among all qualified hitters in the majors.
• De La Cruz brings a seven-game hitting streak into this game. During his last 10 outings he is batting .300 with four doubles, three home runs, five walks and nine RBIs.
• TJ Friedl's .390 OBP and .431 slugging percentage are both team-highs. He has a batting average of .306.
• Including all qualified hitters, he ranks 13th in batting average, 12th in on-base percentage and 75th in slugging percentage.
• Gavin Lux is batting .296 with 14 doubles, a triple, a home run and 24 walks.
• Santiago Espinal has nine doubles and 14 walks while hitting .262.

Cubs vs Reds Head to Head

• 5/30/2025: 6-2 CIN (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/25/2025: 11-8 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/24/2025: 6-4 CIN (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/23/2025: 13-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/29/2024: 3-0 CIN (Favorite: Reds, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/28/2024: 3-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/27/2024: 1-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/31/2024: 13-4 CHC (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/30/2024: 6-3 CIN (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/29/2024: 7-1 CIN (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)

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