Cubs vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for April 12

Odds updated as of 2:11 p.m.

The Sunday schedule in MLB includes a matchup between the Chicago Cubs and the Pittsburgh Pirates.

We've got you covered, in terms of the most important information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Pirates Game Info

• Chicago Cubs (6-8) vs. Pittsburgh Pirates (9-5)
• Date: Sunday, April 12, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and SportsNet PT

Cubs vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-134) | PIT: (+116)
• Spread: CHC: -1.5 (+130) | PIT: +1.5 (-156)
• Total: 12.5 -- Over: (-105) | Under: (-115)

Cubs vs Pirates Probable Starting Pitchers

Probable Pitchers: Jameson Taillon (Cubs) - 0-1, 2.53 ERA vs Bubba Chandler (Pirates) - 0-1, 3.12 ERA

The Cubs will give the nod to Jameson Taillon (0-1, 2.53 ERA), who is eyeing win No. 1 on the season, and the Pirates will turn to Bubba Chandler (0-1, 3.12 ERA). Taillon has a record of 0-2-0 ATS in two starts with a spread this season. Taillon's team lost his only start as a favorite this season. Chandler has started two games with set spreads, and the Pirates went 1-1-0. The Pirates have always been the moneyline underdog when Chandler starts this season.

Cubs vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (52.4%)

Cubs vs Pirates Moneyline

• Pittsburgh is a +116 underdog on the moneyline, while Chicago is a -134 favorite at home.

Cubs vs Pirates Spread

• The Cubs are 1.5-run home favorites on the runline against the Pirates. The Cubs are +130 to cover, and the Pirates are -156.

Cubs vs Pirates Over/Under

• The Cubs-Pirates game on April 12 has been given an over/under of 12.5 runs. The over is set at -105 and the under at -115.

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Cubs vs Pirates Betting Trends

• The Cubs have won in four, or 36.4%, of the 11 contests they have been named as odds-on favorites in this year.
• Chicago has a record of 3-5 in contests when oddsmakers favor them by -134 or more on the moneyline.
• The Cubs and their opponents have gone over in seven of their 14 games with a total set by sportsbooks this season.
• The Cubs have an against the spread mark of 5-9-0 in 14 games with a line this season.
• The Pirates are 4-4 in games they were listed as the moneyline underdog (winning 50% of those games).
• Pittsburgh has a record of 3-1 when playing as a moneyline underdog with odds of +116 or longer (75%).
• In the 14 games oddsmakers have set an over/under for the Pirates, they have combined with opponents to go over the total eight times (8-6-0).
• The Pirates have covered 64.3% of their games this season, going 9-5-0 against the spread.

Cubs Player Leaders

• Nico Hoerner leads Chicago OPS (.903) this season. He has a .308 batting average, an on-base percentage of .422, and a slugging percentage of .481.
• He ranks 30th in batting average, 11th in on-base percentage, and 44th in slugging among qualifying hitters in baseball.
• Hoerner has picked up at least one hit in six straight games. During his last 10 outings he is batting .333 with four doubles, a home run, six walks and eight RBIs.
• Ian Happ has 10 hits, which is best among Chicago batters this season. He's batting .208 with six extra-base hits. He's also slugging .500 with an on-base percentage of .309.
• He ranks 125th in batting average, 112th in on-base percentage and 35th in slugging among qualified hitters.
• Alex Bregman is batting .207 with a .328 slugging percentage and four RBI this year.
• Bregman has recorded at least one base hit in two straight games. In his last five games he is batting .273 with a double, a walk and an RBI.
• Matt Shaw has been key for Chicago with nine hits, an OBP of .268 plus a slugging percentage of .421.

Pirates Player Leaders

• Oneil Cruz has racked up 19 hits with a .618 slugging percentage, both team-high stats for the Pirates. He's batting .345 and with an on-base percentage of .400.
• Including all the qualifying hitters in MLB, his batting average ranks 10th, his on-base percentage ranks 20th, and he is 10th in slugging.
• Cruz hopes to build on a 10-game hitting streak in this matchup. In his last 10 outings he is batting .415 with three doubles, four home runs, three walks and 12 RBIs.
• Ryan O'Hearn has a .414 OBP to lead his team. He has a batting average of .319 while slugging .553.
• Including all qualified hitters, he is 24th in batting average, 15th in on-base percentage and 22nd in slugging percentage.
• Bryan Reynolds is batting .259 with a double, three home runs and eight walks.
• Brandon Lowe has two doubles, three home runs and nine walks while hitting .222.

Cubs vs Pirates Head to Head

• 4/11/2026: 4-3 PIT (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/10/2026: 2-0 PIT (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/17/2025: 8-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/16/2025: 4-1 CHC (Favorite: Pirates, Spread: -1.5, Total: 6.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/15/2025: 4-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/17/2025: 4-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 8/16/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 8/15/2025: 3-2 PIT (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/15/2025: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 6/14/2025: 2-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -235, Underdog Moneyline: +194)

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