Cavaliers vs. Spurs Prediction, Odds, Picks, Best Bets for Dec. 5

Cavaliers vs. Spurs Game Info

• Date: Friday, December 5, 2025
• Time: 7:30 p.m. ET
• Venue: Rocket Arena -- Cleveland, Ohio
• Coverage: FDSOH and FDSSW

The Cleveland Cavaliers (13-10) play the San Antonio Spurs (15-6) as 5-point favorites on Friday, December 5, 2025 at 7:30 p.m. ET on FDSOH and FDSSW. The matchup has an over/under of 238.5 points.

Cavaliers vs. Spurs Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Cavaliers vs. Spurs Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (78.7%)

Cavaliers vs. Spurs Betting Trends

• The Cavaliers have put together an 8-15-0 record against the spread this season.
• In the Spurs' 21 games this season, they have 10 wins against the spread.
• This season, Cavaliers games have hit the over 10 times out of 21 chances.
• Spurs games this year have gone over the total in 11 of 21 opportunities (52.4%).
• Cleveland owns a worse record against the spread in home games (4-9-0) than it does on the road (4-6-0).
• At home, the Cavaliers eclipse the over/under 23.1% of the time (three of 13 games). They hit the over more often in road games, eclipsing the total in 70% of games (seven of 10).
• San Antonio has performed better against the spread at home (6-3-2) than away (4-5-1) this year.
• In 2025-26 a lower percentage of the Spurs' games have finished above the over/under at home (45.5%, five of 11) compared to on the road (60%, six of 10).

Cavaliers Leaders

• Donovan Mitchell averages 30.7 points, 5 rebounds and 5.5 assists, shooting 50.6% from the floor and 38.2% from beyond the arc, with 4 made treys per contest (second in league).
• Evan Mobley averages 19 points, 9 rebounds and 4.1 assists, shooting 50.2% from the field and 37.1% from downtown, with 1.6 made treys per contest.
• De'Andre Hunter averages 16.7 points, 4.5 rebounds and 2.6 assists, shooting 44.8% from the floor and 32.3% from beyond the arc, with 2.1 made 3-pointers per game.
• Jaylon Tyson is averaging 12.5 points, 5 rebounds and 1.8 assists.
• Lonzo Ball is averaging 5.7 points, 4.5 rebounds and 4.9 assists.

Spurs Leaders

• Devin Vassell's numbers on the season are 15.7 points, 3.8 boards and 2.3 assists per contest. He is also sinking 43.8% of his shots from the field and 38.9% from 3-point range, with an average of 2.7 triples.
• Keldon Johnson's numbers on the season are 13 points, 6.5 rebounds and 1.9 assists per contest. He is making 57.7% of his shots from the floor (10th in NBA).
• De'Aaron Fox's numbers on the season are 25 points, 3.6 boards and 6.3 assists per game. He is sinking 49.3% of his shots from the field and 38.6% from 3-point range, with an average of 2.5 triples.
• The Spurs get 13.2 points per game from Harrison Barnes, plus 3.4 boards and 2.2 assists.
• The Spurs are getting 10.9 points, 5.4 rebounds and 1.4 assists per game from Julian Champagnie.

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