Brewers vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 6:11 p.m.

The Milwaukee Brewers are among the MLB teams playing on Friday, versus the Baltimore Orioles.

We've got you covered, in terms of the most important info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Brewers vs Orioles Game Info

• Milwaukee Brewers (95-58) vs. Baltimore Orioles (75-78)
• Date: Friday, September 18, 2026
• Time: 7:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and Brewers.TV

Brewers vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-144) | BAL: (+122)
• Spread: MIL: -1.5 (+106) | BAL: +1.5 (-128)
• Total: 8.5 -- Over: (-108) | Under: (-112)

Brewers vs Orioles Probable Starting Pitchers

Probable Pitchers: Dustin May (Brewers) - 7-9, 4.49 ERA vs Cade Povich (Orioles) - 2-1, 4.05 ERA

The Brewers will give the nod to Dustin May (7-9) against the Orioles and Cade Povich (2-1). May's team is 14-14-0 against the spread this season in his starts. May's team has won 57.1% of his starts when they are favored on the moneyline (8-6). The Orioles have a 4-2-0 ATS record in Povich's six starts with a set spread. The Orioles have been the moneyline underdog in three of Povich's starts this season, and they went 1-2 in those matchups.

Brewers vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (64.6%)

Brewers vs Orioles Moneyline

• The Brewers vs Orioles moneyline has Milwaukee as a -144 favorite, while Baltimore is a +122 underdog at home.

Brewers vs Orioles Spread

• The Brewers are 1.5-run road favorites on the runline against the Orioles. The Brewers are +106 to cover, and the Orioles are -128.

Brewers vs Orioles Over/Under

• A total of 8.5 runs has been set for the Brewers-Orioles game on Sept. 18, with the over available at -108 and the under at -112.

Bet on Milwaukee Brewers vs. Baltimore Orioles on FanDuel today!

Brewers vs Orioles Betting Trends

• The Brewers have come away with 76 wins in the 119 contests they have been listed as the favorites in this season.
• Milwaukee has a record of 43-24 when favored by -144 or more this year.
• The Brewers and their opponents have gone over in 67 of their 152 games with a total set by sportsbooks this season.
• In 152 games with a line this season, the Brewers have a mark of 79-73-0 against the spread.
• The Orioles have won 47.4% of the games this season they were the moneyline underdog (37-41).
• Baltimore is 9-15 (winning just 37.5% of its games) when playing as a moneyline underdog of +122 or longer.
• In the 152 games oddsmakers have set an over/under for the Orioles, they have combined with opponents to go over the total 78 times (78-70-4).
• The Orioles have put together a 79-73-0 record against the spread this season (covering 52% of the time).

Brewers Player Leaders

• Brice Turang leads Milwaukee in slugging percentage (.443) thanks to 56 extra-base hits. He has a .266 batting average and an on-base percentage of .369.
• Among all qualified hitters in baseball, his batting average ranks 52nd, his on-base percentage ranks 17th, and he is 52nd in slugging.
• Turang will look for his third straight game with a hit in this contest. In his last five games he is hitting .375 with a double, a home run, eight walks and three RBIs.
• William Contreras has an OPS of .759, fueled by an OBP of .341 and a team-best slugging percentage of .418 this season. He's batting .271.
• Among qualifying batters, he is 40th in batting average, 53rd in on-base percentage and 75th in slugging percentage.
• Contreras enters this game looking to extend his six-game hit streak. During his last 10 outings he is hitting .238 with two doubles, four home runs, five walks and 14 RBIs.
• Jake Bauers leads his team in OBP (.394) and total hits (121) this season.
• Bauers takes a five-game hitting streak into this game. During his last five outings he is batting .300 with a double, two home runs, three walks and five RBIs.
• Jackson Chourio is batting .286 with a .343 OBP and 67 RBI for Milwaukee this season.

Orioles Player Leaders

• Pete Alonso has 153 hits with a .361 on-base percentage and a .503 slugging percentage, all club-highs for the Orioles. He's batting .267.
• Including all qualified hitters in MLB, he ranks 51st in batting average, 27th in on-base percentage and 13th in slugging percentage.
• Gunnar Henderson has 26 doubles, five triples, 23 home runs and 65 walks while batting .221. He's slugging .397 with an on-base percentage of .306.
• Including all qualified hitters, his batting average puts him 124th, his on-base percentage ranks 110th, and he is 90th in slugging.
• Coby Mayo is hitting .225 with 14 doubles, three triples, 24 home runs and 31 walks.
• Leody Taveras is hitting .217 with 16 doubles, six triples, eight home runs and 40 walks.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!