Astros vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for June 17

Odds updated as of 9:11 p.m.

MLB action on Tuesday includes the Houston Astros taking on the Athletics.

We've got you covered, in terms of the most important info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Astros vs Athletics Game Info

• Houston Astros (41-31) vs. Athletics (30-44)
• Date: Tuesday, June 17, 2025
• Time: 10:05 p.m. ET
• Venue: Sutter Health Park -- West Sacramento, California
• Coverage: NBCS-CA and SCHN

Astros vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-122) | OAK: (+104)
• Spread: HOU: -1.5 (+126) | OAK: +1.5 (-152)
• Total: 11 -- Over: (-108) | Under: (-112)

Astros vs Athletics Probable Starting Pitchers

Probable Pitchers: Jason Alexander (Astros) - 0-0, 18.00 ERA vs JP Sears (Athletics) - 5-5, 5.08 ERA

The Astros will call on Jason Alexander versus the Athletics and JP Sears (5-5). Alexander did not pitch as the moneyline favorite last season. The Athletics are 8-6-0 ATS in Sears' 14 starts with a set spread. The Athletics have been the moneyline underdog in eight of Sears' starts this season, and they went 2-6 in those games.

Astros vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (52%)

Astros vs Athletics Moneyline

• The Astros vs Athletics moneyline has the Astros as a -122 favorite, while the Athletics are a +104 underdog at home.

Astros vs Athletics Spread

• The Astros are 1.5-run favorites on the runline against the Athletics. The Astros are +126 to cover, while the Athletics are -152 to cover.

Astros vs Athletics Over/Under

• Astros versus Athletics on June 17 has an over/under of 11 runs, with the odds on the over -108 and the under set at -112.

Bet on Houston Astros vs. Athletics on FanDuel today!

Astros vs Athletics Betting Trends

• The Astros have been favorites in 48 games this season and have come away with the win 27 times (56.2%) in those contests.
• This season, the Astros have come away with a win 20 times in 33 chances when named as a favorite of at least -122 or better on the moneyline.
• The Astros and their opponents have hit the over in 27 of their 71 games with a total this season.
• The Astros have posted a record of 38-33-0 against the spread this season.
• The Athletics have been the underdog on the moneyline 54 total times this season. They've gone 19-35 in those games.
• The Athletics have gone 16-34 when they have played as a moneyline underdog with odds of +104 or longer (32%).
• The Athletics have combined with their opponents to go over the total 41 times this season for a 41-30-3 record against the over/under.
• The Athletics have gone 36-38-0 against the spread this season.

Astros Player Leaders

• Jeremy Pena leads Houston in OBP (.374), slugging percentage (.478) and total hits (89) this season. He has a .320 batting average.
• Among qualifying hitters in baseball, his batting average ranks seventh, his on-base percentage ranks 23rd, and he is 32nd in slugging.
• Isaac Paredes is batting .252 with nine doubles, a triple, 15 home runs and 37 walks. He's slugging .472 with an on-base percentage of .351.
• Among all qualified, he ranks 87th in batting average, 48th in on-base percentage and 37th in slugging percentage.
• Jose Altuve is batting .274 with a .433 slugging percentage and 31 RBI this year.
• Altuve enters this game with two games in a row with at least one hit. In his last five games he is hitting .333 with three doubles, two home runs, a walk and six RBIs.
• Jake Meyers has three home runs, 16 RBI and a batting average of .295 this season.
• Meyers takes a four-game hitting streak into this game. During his last five outings he is batting .294 with a double and three walks.

Athletics Player Leaders

• Jacob Wilson has an on-base percentage of .396, a slugging percentage of .506, and has 98 hits, all club-highs for the Athletics (while batting .362).
• Including all qualified hitters in the majors, his batting average places him second, his on-base percentage ranks seventh, and he is 15th in slugging.
• Brent Rooker is hitting .275 with 16 doubles, a triple, 15 home runs and 31 walks. He's slugging .491 with an on-base percentage of .349.
• He is currently 42nd in batting average, 50th in on-base percentage and 26th in slugging percentage among all qualifying batters.
• Tyler Soderstrom is hitting .254 with 11 doubles, a triple, 14 home runs and 33 walks.
• Lawrence Butler is hitting .258 with 23 doubles, a triple, 10 home runs and 27 walks.

Astros vs Athletics Head to Head

• 6/16/2025: 3-1 OAK (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/28/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/27/2025: 11-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/12/2024: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 9/11/2024: 5-4 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/10/2024: 4-3 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/24/2024: 8-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/23/2024: 8-2 OAK (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/22/2024: 4-0 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/26/2024: 5-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)

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