Astros vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for June 16

Odds updated as of 2:12 p.m.

On Monday in MLB, the Houston Astros are playing the Athletics.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Athletics Game Info

• Houston Astros (41-30) vs. Athletics (29-44)
• Date: Monday, June 16, 2025
• Time: 10:05 p.m. ET
• Venue: Sutter Health Park -- West Sacramento, California
• Coverage: NBCS-CA and SCHN

Astros vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-156) | OAK: (+132)
• Spread: HOU: -1.5 (-100) | OAK: +1.5 (-120)
• Total: 10.5 -- Over: (-100) | Under: (-122)

Astros vs Athletics Probable Starting Pitchers

Probable Pitchers: Lance McCullers (Astros) - 1-2, 4.91 ERA vs Mitch Spence (Athletics) - 2-1, 3.67 ERA

The Astros will give the ball to Lance McCullers (1-2, 4.91 ERA), who is eyeing win No. 2 on the season, and the Athletics will counter with Mitch Spence (2-1, 3.67 ERA). McCullers and his team have a record of 4-3-0 against the spread when he starts. McCullers' team is 1-3 this season when he starts and they are the moneyline favorite. Spence has started two games with set spreads, and the Athletics covered in both opportunities. The Athletics were the moneyline underdog for two Spence starts this season -- they split the games.

Astros vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (50.1%)

Astros vs Athletics Moneyline

• The Astros vs Athletics moneyline has the Astros as a -156 favorite, while the Athletics are a +132 underdog at home.

Astros vs Athletics Spread

• The Astros are 1.5-run favorites on the runline against the Athletics. The Astros are -100 to cover, while the Athletics are -120 to cover.

Astros vs Athletics Over/Under

• The Astros-Athletics contest on June 16 has been given an over/under of 10.5 runs. The over is set at -100 and the under at -122.

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Astros vs Athletics Betting Trends

• The Astros have won in 27, or 57.4%, of the 47 contests they have been named as odds-on favorites in this year.
• This season, the Astros have come away with a win eight times in 14 chances when named as a favorite of at least -156 or better on the moneyline.
• The Astros and their opponents have hit the over in 27 of their 70 games with a total this season.
• The Astros have an against the spread record of 38-32-0 in 70 games with a line this season.
• The Athletics have won 34% of the games this season they were the moneyline underdog (18-35).
• When they have played as a moneyline underdog with odds of +132 or longer, the Athletics have gone 6-18 (25%).
• The Athletics have played in 73 games with an over/under set, and have combined with their opponents to go over the total 41 times (41-29-3).
• The Athletics are 35-38-0 against the spread this season.

Astros Player Leaders

• Jeremy Pena leads Houston in OBP (.379), slugging percentage (.485) and total hits (89) this season. He has a .325 batting average.
• Among the qualified batters in the majors, his batting average ranks fourth, his on-base percentage ranks 17th, and he is 30th in slugging.
• Isaac Paredes is batting .255 with nine doubles, a triple, 15 home runs and 36 walks, while slugging .478 with an on-base percentage of .353.
• Among all qualified hitters, he ranks 82nd in batting average, 46th in on-base percentage and 32nd in slugging percentage.
• Paredes heads into this game looking to extend his two-game hit streak. During his last five outings he is hitting .263 with two doubles, a home run, two walks and five RBIs.
• Jose Altuve is batting .274 with a .425 slugging percentage and 30 RBI this year.
• Jake Meyers has been key for Houston with 65 hits, an OBP of .358 plus a slugging percentage of .400.
• Meyers takes a three-game hitting streak into this game. During his last five outings he is hitting .235 with a double and three walks.

Athletics Player Leaders

• Jacob Wilson has put up a team-high OBP (.401) and slugging percentage (.513), while pacing the Athletics in hits (98, while batting .367).
• Including all qualifying hitters in the big leagues, his batting average puts him second, his on-base percentage is sixth, and he is 14th in slugging.
• Wilson heads into this matchup on a three-game hitting streak. During his last five outings he is hitting .333 with a double and an RBI.
• Brent Rooker is batting .278 with 16 doubles, a triple, 15 home runs and 30 walks. He's slugging .497 with an on-base percentage of .350.
• His batting average ranks 39th among all qualified players, his on-base percentage is 51st, and he is 23rd in slugging.
• Tyler Soderstrom has 11 doubles, a triple, 14 home runs and 33 walks while batting .254.
• Lawrence Butler is batting .262 with 23 doubles, a triple, 10 home runs and 27 walks.

Astros vs Athletics Head to Head

• 5/28/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/27/2025: 11-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/12/2024: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 9/11/2024: 5-4 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/10/2024: 4-3 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/24/2024: 8-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/23/2024: 8-2 OAK (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/22/2024: 4-0 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/26/2024: 5-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/25/2024: 3-1 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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