Astros vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for June 16

Odds updated as of 9:12 p.m.

Monday's slate in the MLB includes a matchup between the Houston Astros and the Athletics.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Astros vs Athletics Game Info

• Houston Astros (41-30) vs. Athletics (29-44)
• Date: Monday, June 16, 2025
• Time: 10:05 p.m. ET
• Venue: Sutter Health Park -- West Sacramento, California
• Coverage: NBCS-CA and SCHN

Astros vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-116) | OAK: (-102)
• Spread: HOU: -1.5 (+126) | OAK: +1.5 (-152)
• Total: 10 -- Over: (-106) | Under: (-114)

Astros vs Athletics Probable Starting Pitchers

Probable Pitchers: Ryan Gusto (Astros) - 4-3, 4.56 ERA vs Mitch Spence (Athletics) - 2-1, 3.67 ERA

The Astros will give the nod to Ryan Gusto (4-3) against the Athletics and Mitch Spence (2-1). Gusto and his team are 4-5-0 ATS this season when he starts. Gusto's team has won 44.4% of his starts when they are favored on the moneyline (4-5). Spence has started two games with set spreads, and the Athletics covered in both chances. The Athletics were the moneyline underdog for two Spence starts this season -- they split the games.

Astros vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (50.4%)

Astros vs Athletics Moneyline

• The Astros vs Athletics moneyline has the Astros as a -116 favorite, while the Athletics are a -102 underdog at home.

Astros vs Athletics Spread

• The Astros are 1.5-run favorites on the runline against the Athletics. The Astros are +126 to cover, while the Athletics are -152 to cover.

Astros vs Athletics Over/Under

• The Astros-Athletics contest on June 16 has been given an over/under of 10 runs. The over is set at -106 and the under at -114.

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Astros vs Athletics Betting Trends

• The Astros have won in 27, or 57.4%, of the 47 contests they have been named as odds-on favorites in this year.
• This season, the Astros have come away with a win 26 times in 45 chances when named as a favorite of at least -116 or better on the moneyline.
• The Astros and their opponents have hit the over in 27 of their 70 games with a total this season.
• The Astros are 38-32-0 against the spread in their 70 games that had a posted line this season.
• The Athletics have gone 18-35 in games they were listed as the moneyline underdog (winning 34% of those games).
• When they have played as a moneyline underdog with odds of -102 or longer, the Athletics have gone 17-35 (32.7%).
• The Athletics have played in 73 games with an over/under set, and have combined with their opponents to go over the total 41 times (41-29-3).
• The Athletics have covered 47.9% of their games this season, going 35-38-0 ATS.

Astros Player Leaders

• Jeremy Pena leads Houston with 89 hits and an OBP of .379, plus a team-best slugging percentage of .485. He's batting .325.
• Among qualifying hitters in MLB, he ranks fourth in batting average, 17th in on-base percentage, and 30th in slugging.
• Isaac Paredes is hitting .255 with nine doubles, a triple, 15 home runs and 36 walks. He's slugging .478 with an on-base percentage of .353.
• He is 82nd in batting average, 46th in on-base percentage and 32nd in slugging in the major leagues.
• Paredes brings a two-game streak with at least one hit into this contest. In his last five games he is hitting .263 with two doubles, a home run, two walks and five RBIs.
• Jose Altuve has 73 hits this season and has a slash line of .274/.322/.425.
• Jake Meyers has been key for Houston with 65 hits, an OBP of .358 plus a slugging percentage of .400.
• Meyers enters this matchup on a three-game hitting streak. In his last five games he is hitting .235 with a double and three walks.

Athletics Player Leaders

• Jacob Wilson has accumulated an on-base percentage of .401, a slugging percentage of .513, and has 98 hits, all club-bests for the Athletics (while batting .367).
• Including all the qualifying hitters in MLB, his batting average places him second, his on-base percentage ranks sixth, and he is 14th in slugging.
• Wilson brings a three-game hitting streak into this game. In his last five games he is hitting .333 with a double and an RBI.
• Brent Rooker is batting .278 with 16 doubles, a triple, 15 home runs and 30 walks. He's slugging .497 with an on-base percentage of .350.
• He is currently 39th in batting average, 51st in on-base percentage and 23rd in slugging percentage among all qualified hitters.
• Tyler Soderstrom is hitting .254 with 11 doubles, a triple, 14 home runs and 33 walks.
• Lawrence Butler is hitting .262 with 23 doubles, a triple, 10 home runs and 27 walks.

Astros vs Athletics Head to Head

• 5/28/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/27/2025: 11-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/12/2024: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 9/11/2024: 5-4 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/10/2024: 4-3 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/24/2024: 8-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/23/2024: 8-2 OAK (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/22/2024: 4-0 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/26/2024: 5-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/25/2024: 3-1 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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