Arizona vs Iowa State College Basketball Prediction, Odds, Picks, Best Bets for Big 12 Tournament

The top-seeded Arizona Wildcats (30-2, 16-2 Big 12) are taking on the No. 5 seed Iowa State Cyclones (27-6, 12-6 Big 12) in the Big 12 tournament on Friday at T-Mobile Center, at 7 p.m. ET airing on ESPN.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Arizona vs. Iowa State Game Info and Odds

• Game day: Friday, March 13, 2026
• Game time: 7 p.m. ET
• TV channel: ESPN
• Location: Kansas City, Missouri
• Arena: T-Mobile Center

Arizona vs. Iowa State Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Arizona win (61%)

If you plan to place a wager on Arizona-Iowa State outing (in which Arizona is a 4.5-point favorite and the over/under has been set at 143.5 points), below are some betting insights and trends for Friday's game.

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Arizona vs. Iowa State: ATS Betting Stats and Trends

• Arizona has compiled a 19-13-0 ATS record so far this year.
• Iowa State has compiled a 19-14-0 ATS record so far this season.
• When the spread is set as 4.5 or more this season, Arizona (13-12) covers a higher percentage of those games when it is the favorite (52%) than Iowa State (1-1) does as the underdog (50%).
• When playing at home, the Wildcats sport a better record against the spread (9-8-0) compared to their ATS record in road games (5-5-0).
• Against the spread, the Cyclones have performed better at home (9-8-0) than away (5-5-0).
• Arizona's record against the spread in conference games is 11-8-0.
• Iowa State is 12-8-0 against the spread in Big 12 play this season.

Arizona vs. Iowa State: Moneyline Betting Stats

• Arizona has won in 20, or 90.9%, of the 22 contests it has been named as the moneyline favorite in this year.
• The Wildcats have a mark of 17-1 in contests where bookmakers favor them by -194 or better on the moneyline.
• Iowa State has been listed as the moneyline underdog just two other times so far this season, and it split the games.
• The Cyclones have played as a moneyline underdog of +160 or longer in just two games this season, which they split 1-1.
• Arizona has an implied victory probability of 66% according to the moneyline set for this matchup.

Arizona vs. Iowa State Head-to-Head Comparison

• Arizona has a +583 scoring differential, topping opponents by 18.2 points per game. It is putting up 86.5 points per game to rank 14th in college basketball and is allowing 68.3 per contest to rank 44th in college basketball.
• Brayden Burries leads Arizona, putting up 16.2 points per game (208th in college basketball).
• Iowa State is outscoring opponents by 17.2 points per game, with a +568 scoring differential overall. It puts up 81.8 points per game (56th in college basketball) and gives up 64.6 per outing (seventh in college basketball).
• Milan Momcilovic paces Iowa State, averaging 16.8 points per game (167th in college basketball).
• The Wildcats win the rebound battle by an average of 12.4 boards. They are grabbing 40.3 rebounds per game (second in college basketball) compared to their opponents' 27.9 per outing.
• Tobe Awaka averages 9.6 rebounds per game (ranking 17th in college basketball) to lead the Wildcats.
• The Cyclones grab 32.5 rebounds per game (141st in college basketball) while allowing 28.3 per outing to opponents. They outrebound opponents by 4.2 boards per game.
• Joshua Jefferson averages 7.7 rebounds per game (99th in college basketball) to lead the Cyclones.
• Arizona ranks 31st in college basketball with 105.6 points scored per 100 possessions, and fifth in college basketball defensively with 83.4 points conceded per 100 possessions.
• The Cyclones average 106.6 points per 100 possessions on offense (24th in college basketball), and allow 84.2 points per 100 possessions (seventh in college basketball).

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