Arizona vs Iowa State College Basketball Prediction, Odds, Picks, Best Bets for Big 12 Tournament

The No. 1 seed Arizona Wildcats (30-2, 16-2 Big 12) and the No. 5 seed Iowa State Cyclones (27-6, 12-6 Big 12) will look to advance in the Big 12 tournament on Friday as they meet at 7 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Arizona vs. Iowa State Game Info and Odds

• Game day: Friday, March 13, 2026
• Game time: 7 p.m. ET
• TV channel: ESPN
• Location: Kansas City, Missouri
• Arena: T-Mobile Center

Arizona vs. Iowa State Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Arizona win (61%)

Arizona is a 4.5-point favorite against Iowa State on Friday and the over/under has been set at 144.5 points. Here's some betting trends and insights if you are planning on making a wager on the contest.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Arizona vs. Iowa State: ATS Betting Stats and Trends

• Arizona is 19-13-0 ATS this season.
• Iowa State has covered 19 times in 33 matchups with a spread this season.
• Arizona (13-12) covers a higher percentage of games when it is favored by 4.5 points or more this season (52%) than Iowa State (1-1) does as a 4.5+-point underdog (50%).
• The Wildcats have covered the spread in a higher percentage of their home games than road games. They have covered nine times in 17 opportunities at home, and they've covered five times in 10 opportunities in away games.
• The Cyclones' winning percentage against the spread at home is .529 (9-8-0). Away, it is .500 (5-5-0).
• Arizona's record against the spread in conference games is 11-8-0.
• Iowa State is 12-8-0 against the spread in Big 12 games this year.

Arizona vs. Iowa State: Moneyline Betting Stats

• Arizona has been the moneyline favorite in 22 games this season and has come away with the win 20 times (90.9%) in those contests.
• The Wildcats have a win-loss record of 17-1 when favored by -194 or better by bookmakers this year.
• Iowa State has been listed as the moneyline underdog just two other times so far this season, and it split the games.
• The Cyclones have played as a moneyline underdog of +160 or longer in only two games this season, which they split 1-1.
• The moneyline set for this matchup implies Arizona has a 66% chance of coming away with a victory in the contest.

Arizona vs. Iowa State Head-to-Head Comparison

• Arizona outscores opponents by 18.2 points per game (scoring 86.5 per game to rank 14th in college basketball while allowing 68.3 per contest to rank 44th in college basketball) and has a +583 scoring differential overall.
• Arizona's leading scorer, Brayden Burries, is 208th in the nation scoring 16.2 points per game.
• Iowa State outscores opponents by 17.2 points per game (posting 81.8 points per game, 56th in college basketball, and conceding 64.6 per contest, seventh in college basketball) and has a +568 scoring differential.
• Milan Momcilovic's 16.8 points per game paces Iowa State and ranks 167th in college basketball.
• The Wildcats pull down 40.3 rebounds per game (second in college basketball) while conceding 27.9 per outing to their opponents. They outrebound opponents by 12.4 boards per game.
• Tobe Awaka paces the Wildcats with 9.6 rebounds per game (17th in college basketball action).
• The Cyclones pull down 32.5 rebounds per game (141st in college basketball) while allowing 28.3 per outing to opponents. They outrebound opponents by 4.2 boards per game.
• Joshua Jefferson tops the Cyclones with 7.7 rebounds per game (98th in college basketball).
• Arizona averages 105.6 points per 100 possessions (31st in college basketball), while allowing 83.4 points per 100 possessions (fifth in college basketball).
• The Cyclones record 106.6 points per 100 possessions (23rd in college basketball), while giving up 84.2 points per 100 possessions (seventh in college basketball).

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!